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  1. Target

    Pigment epithelium-derived factor

    go.drugbank.com/bio_entities/BE0009068
    TargetHumans

    Neurotrophic protein; induces extensive neuronal differentiation in retinoblastoma cells. Potent inhibitor of angiogenesis. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins...

  2. Target

    Retinoid isomerohydrolase

    go.drugbank.com/bio_entities/BE0009149
    TargetEnzymeHumans

    Critical isomerohydrolase in the retinoid cycle involved in regeneration of 11-cis-retinal, the chromophore of rod and cone opsins. Catalyzes the cleavage and isomerization of all-trans-retinyl fatty acid esters to 11-cis-retinol which i...