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Hydroquinone

go.drugbank.com/drugs/DB09526
ApprovedInvestigational

Hydroquinone is a topical lightening product found in OTC products, and is used to correct skin discoloration associated with disorders of hyperpigmentation including melasma, post-inflammatory hyperpigmention, sunspots, and freckles. It can be used alone, but is more frequently found in combination with other agent...

  1. Drug

    Monobenzone

    go.drugbank.com/drugs/DB00600
    ApprovedWithdrawn

    Monobenzone is the monobenzyl ether of hydroquinone used medically for depigmentation.

    Synonyms: Monobenzyl hydroquinone, Hydroquinone benzyl ether
  2. Drug

    Resorcinol

    go.drugbank.com/drugs/DB11085
    ApprovedInvestigational

    Resorcinol is a 1,3-isomer (or meta-isomer) of benzenediol with the formula C6H4(OH)2. It is used as an antiseptic and disinfectant in topical pharmaceutical products in the treatment of skin disorders and infections such as acne, seborr...

    Synonyms: m-Hydroquinone
  3. Drug

    Arbutin

    go.drugbank.com/drugs/DB11217
    Approved

    Extracted from the dried leaves of bearberry plant in the genus Arctostaphylos and other plants commonly in the Ericaceae family, arbutin is a beta-D-glucopyranoside of DB09526. It is found in foods, over-the-counter drugs, and herbal di...

    Synonyms: hydroquinone O-β-D-glucopyranoside, Hydroquinone-O-beta-D-glucopyranoside
  4. Drug

    t-Butylhydroquinone

    go.drugbank.com/drugs/DB07726
    Experimental

    Synonyms: t-Butyl hydroquinone, 2-tert-Butyl(1,4)hydroquinone
  5. Drug

    Kappadione

    go.drugbank.com/drugs/DB09332
    Approved

    Kappadione is a Vitamin K derivative (chemically, it is menadiol sodium diphosphate), previously approved by FDA prior to 1982 and marketed by Lilly Marketing for this drug has been discontinued and is not available in North America . It...

  6. Drug

    Tretinoin

    go.drugbank.com/drugs/DB00755
    ApprovedInvestigationalNutraceutical

    Tretinoin, also known as all-trans-retinoic acid (ATRA), is a naturally occurring derivative of vitamin A (retinol). It is an oxidation product in the physiological pathway of vitamin A metabolism. In human circulation, tretinoin is norm...

    Mixtures: Hydroquinone 6% /tretinoin 0.05%, Hydroquinone 8% / Tretinoin 0.025%
  7. Drug

    Hydrocortisone

    go.drugbank.com/drugs/DB00741
    ApprovedInvestigationalVet approved

    Hydrocortisone, or cortisol, is a glucocorticoid secreted by the adrenal cortex. Hydrocortisone is used to treat immune, inflammatory, and neoplastic conditions. It was discovered in the 1930s by Edward Kendall and named Compound F, or 1...

    Mixtures: Hydrocortisone 0.5% / Hydroquinone 6%, Hydrocortisone 1% / Hydroquinone 8% / Tretinoin 0.05%
  8. Drug

    Dioxybenzone

    go.drugbank.com/drugs/DB11221
    ApprovedWithdrawn

    Dioxybenzone, or benzophenone-8, is an organic compound derived from DB01878 that is used as a sunscreen agent. It absorbed UV-B and UV-AII rays. Dioxybenzone is an approved sunscreen ingredient in concentrations up to 3% .

    Mixtures: Hydroquinone with sunscreens, Perrigo Hydroquinone with sunscreens
  9. Drug

    Menadione

    go.drugbank.com/drugs/DB00170
    ApprovedNutraceutical

    A synthetic naphthoquinone without the isoprenoid side chain and biological activity, but can be converted to active vitamin K2, menaquinone, after alkylation in vivo.