Search

Displaying results 1 - 10 of 6477 in total
  1. Drug

    TO-901317

    go.drugbank.com/drugs/DB07080
    Experimental

    TO-901317 is an LXRalpha and LXRbeta agonist.

  2. Drug

    Haemophilus influenzae b polysaccharide-tetanus conjugate

    go.drugbank.com/drugs/DB15876
    ApprovedInvestigational

    Synonyms: Haemophilus influenzae type b polysaccharide conjugated to tetanus protein, Haemophilus influenzae type b polysaccharide conjugated to the tetanus protein
  3. Drug

    Linvoseltamab

    go.drugbank.com/drugs/DB17447
    ApprovedInvestigational

    By binding to both targets simultaneously, linvoseltamab redirects T cells toward myeloma cells, forming an immunological synapse that activates T-cell–mediated cytotoxicity. … cells with CD3-expressing T cells.

    Synonyms: human IgG4-based anti-CD3 x anti-BCMA bispecific monoclonal antibody that binds to CD3 and BCMACategories: Bispecific B Cell Maturation Antigen-directed CD3 T Cell Engager
  4. Drug

    Brentuximab vedotin

    go.drugbank.com/drugs/DB08870
    ApprovedInvestigational

    [L1737] Adcetris has also been previously approved by the FDA to treat Hodgkin's lymphoma after relapse, Hodgkin's lymphoma after stem cell transplantation when a patient has a high risk of relapse … This demonstrates meaningful progress in treatment for patients affected by this disease.[L1739]

    Synonyms: Moab, chimeric, SGN-30, to CD30 antigenProducts: ADCETRIS 50 MG IV INFÜZYONLUK ÇÖZELTI KONSANTRESI IÇIN TOZ IÇEREN FLAKON ,FLAKON, 1 ADET
  5. Drug

    Loncastuximab tesirine

    go.drugbank.com/drugs/DB16222
    ApprovedInvestigational

    [A234439] Prognosis is poor and more effective therapies are needed to treat relapsed/refractory cases and improve survival. … [L45206] This therapy was developed by ADC Therapeutics and its accelerated approval for relapsed or refractory B-cell lymphoma is based on promising results from the LOTIS-2 clinical trial.

    Synonyms: Humanized monoclonal immunoglobulin G1 antibody directed against human CD19 conjugated to SG3199 through A protease cleavable valine-alanine linker
  6. Drug

    Pivekimab sunirine

    go.drugbank.com/drugs/DB17337
    ApprovedInvestigational

    Synonyms: Indolino-benzodiazepine compound (sulfonated DGN549-C) conjugated to the humanized anti-CD123 monoclonal antibody (G4723A)
  7. Drug

    AGRO100

    go.drugbank.com/drugs/DB04998
    Investigational

    AGRO100 is an oligonucleotide that functions as an aptamer and binds to nucleolin, a protein found intranuclear in all cells, but uniquely expressed on the surface of tumor cells. … Such binding leads to internalization of the complex, and a strong anti-proliferative response in the tumor cell.

    Synonyms: Nucleic acid aptamer binding to tumor cell nucleon
  8. Drug

    ALT-P1

    go.drugbank.com/drugs/DB18485
    Investigational

    ALT-P1 is a long-acting recombinant human growth hormone fused to an alpha1-antitrypsin variant. It is under investigation for the treatment of growth hormone deficiency.

    Synonyms: Recombinant human growth hormone fused to alpha1-antitrypsin variant
  9. Drug

    Ozuriftamab vedotin

    go.drugbank.com/drugs/DB17422
    Investigational

    Synonyms: Ba-302 conjugated to monomethyl auristatin e
  10. Drug

    ANX-005

    go.drugbank.com/drugs/DB16977
    Investigational

    Synonyms: Humanized Igg4 Monoclonal Antibody Binding To Human C1Q