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Displaying all 7 results
  1. Drug

    Abiraterone

    go.drugbank.com/drugs/DB05812
    ApprovedInvestigational

    [L54773,L54768] As abiraterone has poor oral bioavailability and is susceptible to hydrolysis by esterases, abiraterone acetate was developed as an orally bioavailable prodrug with enhanced stability … [A3811, A260880, L40968] Abiraterone was first approved by the FDA and EMA on April,[A260880] July,[L47745] and September 2011,[A260880] respectively.

    Synonyms: Abiraterone, AbirateronaSalts: Abiraterone acetate
  2. Drug

    Niraparib

    go.drugbank.com/drugs/DB11793
    ApprovedInvestigational

    [L43747] On December 12, 2025, the FDA expanded niraparib and abiraterone acetate (AKEEGA) with prednisone for the treatment of patients with BRCA2-mutated metastatic castration-sensitive prostate cancer

    Categories: niraparib and abiraterone
  3. Indication

    Metastatic Hormone-Sensitive Prostate Cancer (mHSPC)

    go.drugbank.com/conditions/DBCOND0152726
    Drugs: Abiraterone
  4. Drug

    Pocenbrodib

    go.drugbank.com/drugs/DB21616
    Investigational

    Pocenbrodib is under investigation in clinical trial NCT06785636 (Open-Label Study of Pocenbrodib Alone and in Combination With Abiraterone Acetate, Olaparib, or 177Lu-PSMA-617).

  5. Indication

    Metastatic Castration Sensitive Prostate Cancer (mCSPC)

    go.drugbank.com/conditions/DBCOND0154644
    Drugs: Abiraterone · Apalutamide · Darolutamide · Enzalutamide · Niraparib · Prednisone
  6. Indication

    Metastatic Castration-Resistant Prostate Cancer (mCRPC)

    go.drugbank.com/conditions/DBCOND0069854
    Drugs: Abiraterone · Cabazitaxel · Enzalutamide · Lutetium Lu-177 vipivotide tetraxetan · Niraparib · Olaparib +4 more
  7. Target

    Deacylase AADAC

    go.drugbank.com/bio_entities/BE0010087
    EnzymeHumans

    Can also catalyzes the deacetylation of cholesterol acetate (PubMed:18034159). … Participates in the hydrolysis of clinical drugs including acetyl esters compounds such as eslicarbazepine, abiraterone and rifamycins (rifampicin, rifabutin, and rifapentine) and N-acetylarylamine compounds