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DrugBest match

Danazol

go.drugbank.com/drugs/DB01406
ApprovedInvestigational

A synthetic steroid with antigonadotropic and anti-estrogenic activities that acts as an anterior pituitary suppressant by inhibiting the pituitary output of gonadotropins. It possesses some androgenic properties. Danazol has been used in the treatment of endometriosis and some benign breast disorders.

  1. Indication

    Fibrocystic Disease of Breast

    go.drugbank.com/conditions/DBCOND0032889
    Drugs: Danazol
  2. Indication

    Refractory immune thrombocytopenia

    go.drugbank.com/conditions/DBCOND0021524
    Drugs: Danazol · Romiplostim
  3. Indication

    Hereditary Angioedema (HAE)

    go.drugbank.com/conditions/DBCOND0034226
    Drugs: Danazol · Stanozolol · Tranexamic acid
  4. Indication

    Endometriosis

    go.drugbank.com/conditions/DBCOND0001340
    Drugs: Buserelin · Danazol · Goserelin · Leuprolide · Levonorgestrel · Lynestrenol +3 more
  5. Target

    Cytochrome P450 2J2

    go.drugbank.com/bio_entities/BE0003683
    EnzymeHumans

    Catalyzes the monooxygenation of a various xenobiotics, such as danazol, amiodarone, terfenadine, astemizole, thioridazine, tamoxifen, cyclosporin A and nabumetone (PubMed:19923256).