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Displaying results 1 - 10 of 10000 in total
  1. Drug

    Modafinil

    go.drugbank.com/drugs/DB00745
    ApprovedInvestigational

    Modafinil is a stimulant drug marketed as a 'wakefulness promoting agent' and is one of the stimulants used in the treatment of narcolepsy. … Narcolepsy is caused by dysfunction of a family of wakefulness-promoting and sleep-suppressing peptides, the orexins, whose neurons are activated by modafinil.

    Synonyms: 2-((diphenylmethyl)sulfinyl)acetamideCategories: Cytochrome P-450 CYP1A2 Inducers, Cytochrome P-450 Substrates
  2. Drug

    JNJ-27548547

    go.drugbank.com/drugs/DB15372
    Investigational

    JNJ-27548547 is under investigation in clinical trial NCT01705002 (Intravenously Administered Pegylated Liposomal Mitomycin-C Lipid-based Prodrug (PROMITIL) in Cancer Patients With Solid Tumors.).

    Synonyms: PROMITIL
  3. Drug

    Olea europaea pollen

    go.drugbank.com/drugs/DB10378
    Approved

    Olea europaea pollen is the pollen of the Olea europaea plant. Olea europaea pollen is mainly used in allergenic testing.

    Synonyms: Olea europaea pollen, european olive pollen extractMixtures: Western 3 Tree Pollen Mix, Western 3 Tree Pollen Mix
  4. Drug

    Copper

    go.drugbank.com/drugs/DB09130
    ApprovedInvestigational

    Copper is a transition metal and a trace element in the body. It is important to the function of many enzymes including cytochrome c oxidase, monoamine oxidase and superoxide dismutase [FDA Label]. … Copper is commonly used in contraceptive intrauterine devices (IUD) [L801].

    Synonyms: cobre, CopperMixtures: Chela Iron Plus C,b Complex, Complex
  5. Drug

    Human immunoglobulin G

    go.drugbank.com/drugs/DB00028
    ApprovedInvestigational

    Intravenous immunoglobulin (IVIg) is a mixture of IgG1 and other antibodies derived from healthy human plasma via Cohn fractionation.

    Synonyms: Human immunoglobulin G, Immunoglobulin G, humanCategories: Immunoglobulin G, Human Immunoglobulin G
  6. Drug

    Usnea barbata

    go.drugbank.com/drugs/DB14351
    Approved

    Usnea barbata is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

    Synonyms: Usnea barbata, Usnea (Usnea Barbata)
  7. Drug

    European pilchard

    go.drugbank.com/drugs/DB10622
    Approved

    European pilchard allergenic extract is used in allergenic testing.

    Synonyms: European pilchard
  8. Drug

    Prochlorperazine

    go.drugbank.com/drugs/DB00433
    ApprovedInvestigationalVet approved

    Although newer antiemetic agents such as 5-HT3 antagonists are more heavily promoted, prochlorperazine is still widely used in nausea and vomiting.[L6640] … Prochlorperazine, also known as compazine, is a piperazine phenothiazine and first-generation antipsychotic drug that is used for the treatment of severe nausea and vomiting, as well as short-term management

    Synonyms: 2-Chloro-10-(3-(1-methyl-4-piperazinyl)propyl)-phenothiazine, 2-Chloro-10-(3-(4-methyl-1-piperazinyl)propyl)phenothiazineCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  9. Drug

    Morphine

    go.drugbank.com/drugs/DB00295
    ApprovedInvestigational

    [A176035] It is a potent analgesic, though its use is limited due to tolerance, withdrawal, and the risk of abuse. … [A176050] Morphine is still routinely used today, though there are a number of semi-synthetic opioids of varying strength such as [codeine], [fentanyl], [methadone], [hydrocodone], [hydromorphone], [meperidine

    Categories: Cytochrome P-450 Substrates, P-glycoprotein substratesSynonyms: (5R,6S,9R,13S,14R)-4,5-epoxy-N-methyl-7-morphinen-3,6-diol, (7R,7AS,12bs)-3-methyl-2,3,4,4a,7,7a-hexahydro-1H-4,12-methano[1]benzofuro[3,2-e]isoquinoline-7,9-diol
  10. Drug

    Copper oxodotreotide Cu-64

    go.drugbank.com/drugs/DB15873
    Approved

    [A220348] Further studies should be performed to compare the two tracers. … [A220348] Copper Cu 64 dotatate has a longer half-life and can be produced once a day as opposed to several times a day, and lower positron energy lending to improved spatial resolution.

    Synonyms: Copper 64-DOTA-tate, Copper Cu-64 dotatateCategories: Copper Radioisotopes