Advanced Filter

Filter by Group

Filter by Market Availability

Clear
Displaying drugs 3051 - 3075 of 11512 in total

Lorcaserin

Lorcaserin (previously APD-356), a highly selective 5HT2C receptor agonist, is used for the treatment of obesity. It has been shown to reduce body weight and food intake in animal models of obesity, and it is thought that targeting the 5HT2C receptor may alter body weight by regulating satiety. Lorcaserin is...
Approved
Withdrawn
Matched Description: … that found that patients treated with lorcaserin may have a higher risk of cancer. ... Lorcaserin (previously APD-356), a highly selective 5HT2C receptor agonist, is used for the treatment ... Lorcaserin is marketed as a salt form called Belviq, which is lorcaserin hydrochloride. …

Quinagolide

Quinagolide is a non-ergot-derived selective dopamine D2 receptor agonist used for the treatment of elevated levels of prolactin or hyperprolactinaemia. Hyperprolalctinaemia is associated with gonadal dysfunction, including infertility and reduced libido, as well as long-term complications such as osteoporosis . Newer dopamine receptor agonists such as quinagolide and DB00248 are...
Approved
Investigational
Matched Description: … Quinagolide is a non-ergot-derived selective dopamine D2 receptor agonist used for the treatment of elevated ... Quinagolide exists as a racemate and its relevant clinical activity is mediated predominantly by the ... hydrochloride salt form and is marketed as oral tablets under the brand name Norprolac contained as a …

Artemisia annua pollen

Artemisia annua pollen is the pollen of the Artemisia annua plant. Artemisia annua pollen is mainly used in allergenic testing.
Approved

Peginterferon alfa-2a

Peginterferon alfa-2a is a form of recombinant interferon used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most...
Approved
Investigational
Matched Description: … Peginterferon alfa-2a is a form of recombinant interferon used as part of combination therapy to treat ... HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 ... Use of Peginterferon alfa-2a is associated with a wide range of severe adverse effects including the …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Cangrelor

Cangrelor is an intravenous, direct-acting, reversible P2Y12 inhibitor for patients undergoing percutaneous coronary intervention (PCI) who have not been yet treated by oral P2Y12 inhibitors. An advantage Cangrelor provides over oral P2Y12 inhibitors (such as prasugrel, ticagrelor, and clopidogrel) is that it is an active drug not requiring metabolic conversion...
Approved
Matched Description: … and clopidogrel) is that it is an active drug not requiring metabolic conversion therefore providing a …

Inositol nicotinate

Inositol nicotinate, also known as Inositol hexaniacinate/hexanicotinate or "no-flush niacin", is a niacin ester and vasodilator. It is used in food supplements as a source of niacin (vitamin B3), where hydrolysis of 1 g (1.23 mmol) inositol hexanicotinate yields 0.91 g nicotinic acid and 0.22 g inositol. Niacin exists in...
Approved
Withdrawn
Matched Description: … Inositol nicotinate, also known as Inositol hexaniacinate/hexanicotinate or "no-flush niacin", is a niacin ... It is used in food supplements as a source of niacin (vitamin B3), where hydrolysis of 1 g (1.23 mmol ... Inositol nicotinate is prescribed in Europe under the name Hexopal as a symptomatic treatment for severe …

Levosimendan

Levosimendan increases calcium sensitivity to myocytes by binding to troponin C in a calcium dependent manner. This increases contractility without raising calcium levels. It also relaxes vascular smooth muscle by opening adenosine triphosphate sensitive potassium channels. Levosimendan is used to manage acutely decompensated congestive heart failure.
Approved
Investigational
Matched Description: … Levosimendan increases calcium sensitivity to myocytes by binding to troponin C in a calcium dependent …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Ethiodized oil

Ethiodized oil is used by injection as a radio-opaque contrast agent. The composition of the oil is comprised of iodine combined with ethyl esters of fatty acids of poppyseed oil. And although these esters are primarily as ethyl monoiodostearate and ethyl diiodostearate, the actual, specific structure is unknown.
Approved
Investigational
Matched Description: … Ethiodized oil is used by injection as a radio-opaque contrast agent. …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Edaravone

Edaravone is a free radical scavenger and neuroprotective agent with antioxidant properties. It has three tautomers. Edaravone works to scavenge reactive oxygen species, which have been implicated in neurological disorders, such as amyotrophic lateral sclerosis (ALS) and cerebral ischemia.[A19140,L44007,A254257] The intravenous formulation of edaravone was first approved in Japan in...
Approved
Investigational
Matched Description: … Edaravone is a free radical scavenger and neuroprotective agent with antioxidant properties. ... 2019, in response to the request made by the Committee for Medicinal Products for Human Use (CHMP) for a …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Iopamidol

Iopamidol is a contrast agent developed by Bracco with nonionic, low-osmolar properties.
Approved
Matched Description: … Iopamidol is a contrast agent developed by Bracco with nonionic, low-osmolar properties. …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Hydroxyethyl Starch

Hydroxyethyl starch (HES/HAES) is a nonionic starch derivative. Hydroxyethyl starches (HES) are synthetic colloids commonly used for fluid resuscitation to replace intravascular volume. HES is a general term and can be sub-classified according to average molecular weight, molar substitution, concentration, C2/C6 ratio and Maximum Daily Dose.
Approved
Matched Description: … Hydroxyethyl starch (HES/HAES) is a nonionic starch derivative. ... HES is a general term and can be sub-classified according to average molecular weight, molar substitution …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Mannitol

Mannitol is an osmotic diuretic that is metabolically inert in humans and occurs naturally, as a sugar or sugar alcohol, in fruits and vegetables. Mannitol elevates blood plasma osmolality, resulting in enhanced flow of water from tissues, including the brain and cerebrospinal fluid, into interstitial fluid and plasma. As a...
Approved
Investigational
Matched International brands: … Mannisol A …
Matched Description: … Mannitol is an osmotic diuretic that is metabolically inert in humans and occurs naturally, as a sugar ... As a result, cerebral edema, elevated intracranial pressure, and cerebrospinal fluid volume and pressure ... established; the promotion of urinary excretion of toxic substances; as an Antiglaucoma agent; and as a …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Gelatin

Gelatin is a multifunctional ingredient that is used in foods, pharmaceuticals, cosmetics, and photographic films as a gelling agent, stabilizer, thickener, emulsifier, as well as film former. As a thermoreversible hydrocolloid with a small gap between its melting and gelling temperatures, gelatin provides unique advantages over carbohydrate-based gelling agents. Gelatin...
Approved
Vet approved
Withdrawn
Matched Description: … [A32432] As a thermoreversible hydrocolloid with a small gap between its melting and gelling temperatures ... [L2121] Fish skins from a number of fish species a type of substance that has been comprehensively ... and gelling temperatures over a much larger range than mammalian gelatins but have a sufficiently high …

Inotersen

Inotersen is a transthyretin-directed antisense oligonucleotide for the treatment of the polyneuropathy caused by hereditary transthyretin-mediated amyloidosis in adults. It was FDA approved in October 2018. Inotersen has been shown to improve the course of neurologic disease and quality of life in patients with hereditary transthyretin amyloidosis . Hereditary transthyretin...
Approved
Investigational
Matched Description: … Inotersen is a transthyretin-directed antisense oligonucleotide for the treatment of the polyneuropathy …

Diatrizoate

A commonly used x-ray contrast medium. As diatrizoate meglumine and as Diatrizoate sodium, it is used for gastrointestinal studies, angiography, and urography.
Approved
Vet approved
Matched Description: … A commonly used x-ray contrast medium. …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Ketamine

Ketamine is an NMDA receptor antagonist with a potent anesthetic effect. It was developed in 1963 as a replacement for phencyclidine (PCP) by Calvin Stevens at Parke Davis Laboratories. It started being used for veterinary purposes in Belgium and in 1964 was proven that compared to PCP, it produced minor...
Approved
Vet approved
Matched Description: … Ketamine is an NMDA receptor antagonist with a potent anesthetic effect. ... [A31869] It was developed in 1963 as a replacement for phencyclidine (PCP) by Calvin Stevens at Parke …

Ticagrelor

Ticagrelor, or AZD6140, was first described in the literature in 2003.[A204170,A2903] Ticagrelor is an ADP derivative developed for its P2Y12 receptor antagonism. Unlike clopidogrel, ticagrelor is not a prodrug. It is marketed by Astra Zeneca as Brilinta in the US and Brilique or Possia in the EU, . Ticagrelor was...
Approved
Matched Description: … [A2903] Unlike [clopidogrel], ticagrelor is not a prodrug. …

Thiabendazole

2-Substituted benzimidazole first introduced in 1962. It is active against a variety of nematodes and is the drug of choice for strongyloidiasis. It has CNS side effects and hepatototoxic potential. (From Smith and Reynard, Textbook of Pharmacology, 1992, p919)
Approved
Vet approved
Matched Description: … It is active against a variety of nematodes and is the drug of choice for strongyloidiasis. …

Indomethacin

Indometacin, or indomethacin, is a non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, and antipyretic properties. NSAIDs consist of agents that are structurally unrelated; the NSAID chemical classification of indometacin is an indole-acetic acid derivative with the chemical name 1- (p-chlorobenzoyl)25-methoxy-2-methylindole-3-acetic acid. The pharmacological effect of indometacin is not fully understood,...
Approved
Investigational
Matched Description: … Indometacin, or indomethacin, is a non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory ... Intravenous indometacin is administered to close a hemodynamically significant patent ductus arteriosus ... effective in reducing ocular inflammation in clinical studies, topical NSAIDs were also associated with a …

Mangafodipir

Mangafodipir is a contrast agent used as a diagnostic tool administered intravenously to enhance contrast in magnetic resonance imaging (MRI) of the liver and pancreas. This drug is made up of paramagnetic manganese (II) ions combined with the chelating agent fodipir (dipyridoxyl diphosphate, DPDP). Manganese absorption into the tissues that...
Approved
Investigational
Withdrawn
Matched Description: … Mangafodipir is a contrast agent used as a diagnostic tool administered intravenously to enhance contrast …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Sonidegib

Sonidegib is a Hedgehog signaling pathway inhibitor (via smoothened antagonism) developed as an anticancer agent by Novartis. It was FDA approved in 2015 for the treatment of basal cell carcinoma.
Approved
Investigational
Matched Description: … Sonidegib is a Hedgehog signaling pathway inhibitor (via smoothened antagonism) developed as an anticancer …
Matched Categories: … Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …

Ferrous ascorbate

Approved
Matched Categories: … Compounds used in a research, industrial, or household setting …

Colestipol

Bile acid sequestrants like colestipol have been in use since the 1970s.[FDA Label, F4555, F4567, L6262] And even though such an agent may very well be useful in reducing elevated cholesterol levels and decreasing the risk for atherosclerotic vascular disease due to hypercholesterolemia, colestipol is still generally only employed as...
Approved
Matched Categories: … Compounds used in a research, industrial, or household setting …

Ioversol

Ioversol is a non-ionic compound with a tri-iodinated benzene ring used as a contrast dye in diagnostic procedures to visualize different types of organs and tissues. Iodine has a high atomic density, which gives it the ability to attenuate X-rays. The intravascular administration of iodine compounds, such as ioversol, enhances...
Approved
Matched Description: … Ioversol is a non-ionic compound with a tri-iodinated benzene ring used as a contrast dye in diagnostic ... [L41780] Iodine has a high atomic density, which gives it the ability to attenuate X-rays. ... [L41780] Ioversol is a highly hydrophilic agent considered to be generally safe[L41790]; however, serious …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Benperidol

Benperidol has been used in trials studying the treatment of Dementia, Depression, Schizophrenia, Anxiety Disorders, and Psychosomatic Disorders, among others.
Approved
Investigational
Displaying drugs 3051 - 3075 of 11512 in total