Displaying drugs 3476 - 3500 of 4242 in total
Gemfibrozil
Gemfibrozil is a fibric acid agent, similar to clofibrate, used to treat Type IIb, IV, and V hyperlipidemias.[A185777,L8525] Gemfibrozil is not a first line treatment and is prescribed to patients who have not responded adequately to weight loss, diet, exercise, and other medications. Gemfibrozil was granted FDA approval on 21...
Approved
Matched Synonyms: … 2,2-Dimethyl-5-(2,5-xylyloxy)valeric acid …
Matched Iupac: … 5-(2,5-dimethylphenoxy)-2,2-dimethylpentanoic acid …
Matched Description: … Gemfibrozil is a fibric acid agent, similar to [clofibrate], used to treat Type IIb, IV, and V hyperlipidemias ... responded adequately to weight loss, diet, exercise, and other medications. ... [A185777,L8525] Gemfibrozil is not a first line treatment and is prescribed to patients who have not …
Matched Categories: … Drug-Related Side Effects and Adverse Reactions ... Metabolic Side Effects of Drugs and Substances ... Acids, Acyclic ... Carboxylic Acids ... Fatty Acids …
Matched Iupac: … 5-(2,5-dimethylphenoxy)-2,2-dimethylpentanoic acid …
Matched Description: … Gemfibrozil is a fibric acid agent, similar to [clofibrate], used to treat Type IIb, IV, and V hyperlipidemias ... responded adequately to weight loss, diet, exercise, and other medications. ... [A185777,L8525] Gemfibrozil is not a first line treatment and is prescribed to patients who have not …
Matched Categories: … Drug-Related Side Effects and Adverse Reactions ... Metabolic Side Effects of Drugs and Substances ... Acids, Acyclic ... Carboxylic Acids ... Fatty Acids …
4-Hydroxy-1,2,5-oxadiazole-3-carboxylic acid
Experimental
Matched Name: … 4-Hydroxy-1,2,5-oxadiazole-3-carboxylic acid …
Matched Iupac: … 4-hydroxy-1,2,5-oxadiazole-3-carboxylic acid …
Matched Iupac: … 4-hydroxy-1,2,5-oxadiazole-3-carboxylic acid …
4-(Acetylamino)-3-[(Aminoacetyl)Amino]Benzoic Acid
Experimental
Matched Name: … 4-(Acetylamino)-3-[(Aminoacetyl)Amino]Benzoic Acid …
[(2-Ethoxy-1-Naphthoyl)Amino]Methylboronic Acid
Experimental
Matched Name: … [(2-Ethoxy-1-Naphthoyl)Amino]Methylboronic Acid …
Matched Iupac: … {[(2-ethoxynaphthalen-1-yl)formamido]methyl}boronic acid …
Matched Iupac: … {[(2-ethoxynaphthalen-1-yl)formamido]methyl}boronic acid …
3-(2-Aminoethyl)-4-(Aminomethyl)Heptanedioic Acid
Experimental
Matched Name: … 3-(2-Aminoethyl)-4-(Aminomethyl)Heptanedioic Acid …
Matched Iupac: … (3R,4S)-3-(2-aminoethyl)-4-(aminomethyl)heptanedioic acid …
Matched Iupac: … (3R,4S)-3-(2-aminoethyl)-4-(aminomethyl)heptanedioic acid …
5-(2-Chlorophenyl)Furan-2-Carboxylic Acid
Experimental
Matched Name: … 5-(2-Chlorophenyl)Furan-2-Carboxylic Acid …
Matched Iupac: … 5-(2-chlorophenyl)furan-2-carboxylic acid …
Matched Iupac: … 5-(2-chlorophenyl)furan-2-carboxylic acid …
[2(Formyl-Hydroxy-Amino)-Ethyl]-Phosphonic Acid
Experimental
Matched Name: … [2(Formyl-Hydroxy-Amino)-Ethyl]-Phosphonic Acid …
Matched Iupac: … [2-(N-hydroxyformamido)ethyl]phosphonic acid …
Matched Iupac: … [2-(N-hydroxyformamido)ethyl]phosphonic acid …
DEHYDRO-2(S)-AMINO-6-BORONOHEXANOIC ACID
Experimental
Matched Name: … DEHYDRO-2(S)-AMINO-6-BORONOHEXANOIC ACID …
5-[2-(TRIFLUOROMETHYL)PHENYL]-2-FUROIC ACID
Experimental
Matched Name: … 5-[2-(TRIFLUOROMETHYL)PHENYL]-2-FUROIC ACID …
Matched Iupac: … 5-[2-(trifluoromethyl)phenyl]furan-2-carboxylic acid …
Matched Iupac: … 5-[2-(trifluoromethyl)phenyl]furan-2-carboxylic acid …
(2S)-2-(4-ethylphenoxy)-3-phenylpropanoic acid
Experimental
Matched Name: … (2S)-2-(4-ethylphenoxy)-3-phenylpropanoic acid …
Matched Iupac: … (2S)-2-(4-ethylphenoxy)-3-phenylpropanoic acid …
Matched Iupac: … (2S)-2-(4-ethylphenoxy)-3-phenylpropanoic acid …
4-(2-HYDROXY-4-FLUOROPHENYLTHIO)-BUTYLPHOSPHONIC ACID
Experimental
Matched Name: … 4-(2-HYDROXY-4-FLUOROPHENYLTHIO)-BUTYLPHOSPHONIC ACID …
Matched Iupac: … [(1E)-4-[(5-fluoro-2-hydroxyphenyl)sulfanyl]but-1-en-1-yl]phosphonic acid …
Matched Iupac: … [(1E)-4-[(5-fluoro-2-hydroxyphenyl)sulfanyl]but-1-en-1-yl]phosphonic acid …
1-PHENYL-1H-PYRAZOLE-4-CARBOXYLIC ACID
Experimental
Matched Name: … 1-PHENYL-1H-PYRAZOLE-4-CARBOXYLIC ACID …
Matched Iupac: … 1-phenyl-1H-pyrazole-4-carboxylic acid …
Matched Iupac: … 1-phenyl-1H-pyrazole-4-carboxylic acid …
Lumacaftor
Lumacaftor is a drug used in combination with DB08820 as the fixed dose combination product Orkambi for the management of Cystic Fibrosis (CF) in patients aged 6 years and older. Cystic Fibrosis is an autosomal recessive disorder caused by one of several different mutations in the gene for the Cystic...
Approved
Matched Synonyms: … 1-(2,2-difluoro-2H-1,3-benzodioxol-5-yl)cyclopropane-1-carbonyl]amino}-3-methylpyridin-2-yl)benzoic acid …
Matched Iupac: … 3-{6-[1-(2,2-difluoro-2H-1,3-benzodioxol-5-yl)cyclopropaneamido]-3-methylpyridin-2-yl}benzoic acid …
Matched Description: … , or delta-F508 (ΔF508), in which a deletion in the amino acid phenylalanine at position 508 results ... be statistically significant, but minimal, with only a 2.6-3.0% change from baseline with more than 70% ... The most common mutation, affecting approximately 70% of patients with CF worldwide, is known as F508del-CFTR …
Matched Categories: … ivacaftor and lumacaftor …
Matched Iupac: … 3-{6-[1-(2,2-difluoro-2H-1,3-benzodioxol-5-yl)cyclopropaneamido]-3-methylpyridin-2-yl}benzoic acid …
Matched Description: … , or delta-F508 (ΔF508), in which a deletion in the amino acid phenylalanine at position 508 results ... be statistically significant, but minimal, with only a 2.6-3.0% change from baseline with more than 70% ... The most common mutation, affecting approximately 70% of patients with CF worldwide, is known as F508del-CFTR …
Matched Categories: … ivacaftor and lumacaftor …
Allogenic bone marrow-derived mesenchymal stem cells
Investigational
Matched Synonyms: … Allogeneic bone marrow derived human mesenchymal stem cells …
Daglutril
Daglutril is an orally active, mixed neutral endopeptidase/endothelin converting enzyme inhibitor under development for the treatment of essential hypertension and congestive heart failure.
Investigational
Matched Synonyms: … Ethoxycarbonyl-4-phenylbutyl)cyclopentanecarboxamido}-2-oxo-2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl)acetic acid …
Matched Iupac: … oxo-2-(2-phenylethyl)propyl]cyclopentaneamido}-2-oxo-2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl]acetic acid …
Matched Description: … endothelin converting enzyme inhibitor under development for the treatment of essential hypertension and …
Matched Iupac: … oxo-2-(2-phenylethyl)propyl]cyclopentaneamido}-2-oxo-2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl]acetic acid …
Matched Description: … endothelin converting enzyme inhibitor under development for the treatment of essential hypertension and …
PTX-100
Investigational
Matched Synonyms: … 2-benzyl-4-(5-methyl-3H-imidazol-4-ylmethyl)-3-oxo-piperazine-1-carbonyl]- amino}-4methyl-pentanoic acid …
Matched Iupac: … -2-benzyl-4-[(4-methyl-1H-imidazol-5-yl)methyl]-3-oxopiperazine-1-carbonyl]amino}-4-methylpentanoic acid …
Matched Iupac: … -2-benzyl-4-[(4-methyl-1H-imidazol-5-yl)methyl]-3-oxopiperazine-1-carbonyl]amino}-4-methylpentanoic acid …
2,2-Dimethylthiazolidine-4-Carboxylic Acid;(Dmt)Thiazolidine
Experimental
Matched Name: … 2,2-Dimethylthiazolidine-4-Carboxylic Acid;(Dmt)Thiazolidine …
Matched Iupac: … (4R)-2,2-dimethyl-1,3-thiazolidine-4-carboxylic acid …
Matched Iupac: … (4R)-2,2-dimethyl-1,3-thiazolidine-4-carboxylic acid …
3-(Oxalyl-Amino)-Naphthalene-2-Carboxylic Acid
Experimental
Matched Name: … 3-(Oxalyl-Amino)-Naphthalene-2-Carboxylic Acid …
Matched Iupac: … 3-(carboxyformamido)naphthalene-2-carboxylic acid …
Matched Iupac: … 3-(carboxyformamido)naphthalene-2-carboxylic acid …
2-Amino-3-(Diethoxy-Phosphoryloxy)-Propionic Acid
Experimental
Matched Name: … 2-Amino-3-(Diethoxy-Phosphoryloxy)-Propionic Acid …
Matched Iupac: … (2S)-2-amino-3-[(diethoxyphosphoryl)oxy]propanoic acid …
Matched Iupac: … (2S)-2-amino-3-[(diethoxyphosphoryl)oxy]propanoic acid …
Cytidine-5'-Monophosphate-5-N-Acetylneuraminic Acid
A nucleoside monophosphate sugar which donates N-acetylneuraminic acid to the terminal sugar of a ganglioside or glycoprotein. [PubChem]
Experimental
Matched Name: … Cytidine-5'-Monophosphate-5-N-Acetylneuraminic Acid …
Matched Iupac: … (hydroxy)phosphoryl)oxy]-5-acetamido-4-hydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-2-carboxylic acid …
Matched Description: … A nucleoside monophosphate sugar which donates N-acetylneuraminic acid to the terminal sugar of a ganglioside …
Matched Iupac: … (hydroxy)phosphoryl)oxy]-5-acetamido-4-hydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-2-carboxylic acid …
Matched Description: … A nucleoside monophosphate sugar which donates N-acetylneuraminic acid to the terminal sugar of a ganglioside …
2-Amino-4-(Hydroxymethyl-Phosphinyl)Butanoic Acid
Experimental
Matched Name: … 2-Amino-4-(Hydroxymethyl-Phosphinyl)Butanoic Acid …
Matched Iupac: … (2R)-2-amino-4-[hydroxy(methyl)phosphoryl]butanoic acid …
Matched Iupac: … (2R)-2-amino-4-[hydroxy(methyl)phosphoryl]butanoic acid …
D-naphthyl-1-acetamido boronic acid alanine
Experimental
Matched Name: … D-naphthyl-1-acetamido boronic acid alanine …
N-(M-Trifluoromethylphenyl) Phenoxazine-4,6-Dicarboxylic Acid
Experimental
Matched Name: … N-(M-Trifluoromethylphenyl) Phenoxazine-4,6-Dicarboxylic Acid …
Matched Iupac: … 10-[3-(trifluoromethyl)phenyl]-10H-phenoxazine-4,6-dicarboxylic acid …
Matched Iupac: … 10-[3-(trifluoromethyl)phenyl]-10H-phenoxazine-4,6-dicarboxylic acid …
4-O-methyl-beta-D-glucuronic acid
Experimental
Matched Name: … 4-O-methyl-beta-D-glucuronic acid …
Matched Iupac: … (2S,3S,4R,5R,6R)-4,5,6-trihydroxy-3-methoxyoxane-2-carboxylic acid …
Matched Iupac: … (2S,3S,4R,5R,6R)-4,5,6-trihydroxy-3-methoxyoxane-2-carboxylic acid …
(2s)-4-(Beta-Alanylamino)-2-Aminobutanoic Acid
Experimental
Matched Name: … (2s)-4-(Beta-Alanylamino)-2-Aminobutanoic Acid …
Matched Iupac: … (2S)-2-amino-4-(3-aminopropanamido)butanoic acid …
Matched Iupac: … (2S)-2-amino-4-(3-aminopropanamido)butanoic acid …
Displaying drugs 3476 - 3500 of 4242 in total