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Displaying drugs 4126 - 4150 of 10342 in total
(1E)-5-(1-piperidin-4-yl-3-pyridin-4-yl-1h-pyrazol-4-yl)-2,3-dihydro-1h-inden-1-one oxime is a solid. This compound belongs to the phenylpyrazoles. These are compounds containing a phenylpyrazole skeleton, which consists of a pyrazole bound to a phenyl group. It targets the protein serine/threonine-protein kinase B-raf.
Experimental
Matched Name: … (1E)-5-(1-piperidin-4-yl-3-pyridin-4-yl-1H-pyrazol-4-yl)-2,3-dihydro-1H-inden-1-one oxime …
Matched Iupac: … N-[(1E)-5-[1-(piperidin-4-yl)-3-(pyridin-4-yl)-1H-pyrazol-4-yl]-2,3-dihydro-1H-inden-1-ylidene]hydroxylamine …
Matched Description: … (1E)-5-(1-piperidin-4-yl-3-pyridin-4-yl-1h-pyrazol-4-yl)-2,3-dihydro-1h-inden-1-one oxime is a solid. …
Neuradiab is under investigation in clinical trial NCT00615186 (Glioblastoma Multiforme (GBM) Locoregional Agent Survival Study - Anti-tenascin Radiolabeled Antibody Therapy).
Investigational
Efonidipine is a calcium channel blocker of the dihydropyridine class, commercialized by Shionogi & Co. (Japan). Initially, it was marketed in 1995 under the trade name, Landel. The drug has been shown to block T-type in addition to L-type calcium channels [A7844, A32001]. It has also been studied in atherosclerosis...
Experimental
Matched Iupac: … )-1,4-dihydropyridine-3-carboxylate ... 2-[benzyl(phenyl)amino]ethyl 5-(5,5-dimethyl-2-oxo-1,3,2λ⁵-dioxaphosphinan-2-yl)-2,6-dimethyl-4-(3-nitrophenyl …
Matched Salts cas: … 111011-53-1
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Experimental
Matched Name: … [1-HYDROXY-2-(1,1':3',1''-TERPHENYL-3-YLOXY)ETHANE-1,1-DIYL]BIS(PHOSPHONIC ACID) …
Matched Iupac: … [1-hydroxy-2-({3'-phenyl-[1,1'-biphenyl]-3-yl}oxy)-1-phosphonoethyl]phosphonic acid …
Experimental
Matched Name: … 4-ethyl-5-methyl-2-(1H-tetrazol-5-yl)-1,2-dihydro-3H-pyrazol-3-one …
Matched Iupac: … 4-ethyl-5-methyl-2-(1H-1,2,3,4-tetrazol-5-yl)-2,3-dihydro-1H-pyrazol-3-one …
Experimental
Matched Iupac: … 2-amino-1H-1,3-benzodiazol-6-ol …
Investigational
Matched Synonyms: … Piperazine, 1-(2-(bis(4-fluorophenyl)methoxy)ethyl)-4-(3-phenyl-2-propen-1-yl)- ... 1-(2-(bis(4-fluorophenyl)methoxy)ethyl)-4-(3-phenyl-2-propenyl)piperazine ... Piperazine, 1-(2-(bis(4-fluorophenyl)methoxy)ethyl)-4-(3-phenyl-2-propenyl)- …
Matched Iupac: … 1-{2-[bis(4-fluorophenyl)methoxy]ethyl}-4-[(2E)-3-phenylprop-2-en-1-yl]piperazine …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Experimental
Matched Name: … 4-[(1S,2R,5S)-4,4,8-TRIMETHYL-3-OXABICYCLO[3.3.1]NON-7-EN-2-YL]PHENOL …
Matched Iupac: … 4-[(1S,2R,5S)-4,4,8-trimethyl-3-oxabicyclo[3.3.1]non-7-en-2-yl]phenol …
Experimental
Matched Synonyms: … 3-deoxy-3-fluoro-D-erythro-α-L-manno-non-2-ulopyranosonic acid …
Matched Name: … 2,6-anhydro-3-deoxy-3-fluoronononic acid …
Matched Iupac: … (2R,3R,4R,5R,6S)-3-fluoro-2,4,5-trihydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-2-carboxylic acid …
Experimental
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Experimental
Matched Name: … (3r)-1-Acetyl-3-Methylpiperidine …
Matched Iupac: … 1-[(3R)-3-methylpiperidin-1-yl]ethan-1-one …
Experimental
Matched Iupac: … 6-hydroxy-2H-1,3-benzoxathiol-2-one …
Experimental
Matched Name: … (3R)-3-(aminomethyl)-9-methoxy-1,2,3,4-tetrahydro-5H-[1]benzothieno[3,2-e][1,4]diazepin-5-one …
Matched Iupac: … (12R)-12-(aminomethyl)-4-methoxy-8-thia-11,14-diazatricyclo[7.5.0.0^{2,7}]tetradeca-1(9),2(7),3,5-tetraen …
Experimental
Matched Iupac: … -1(27),9,11,15,21(29),22,24(28),25-octaene-18-carbonitrile ... (5S,18R)-31-oxo-20-oxa-2,6,11,13-tetraazahexacyclo[19.6.2.1^{2,5}.1^{15,19}.0^{9,13}.0^{24,28}]hentriaconta …
VX-702 is a small molecule investigational oral anti-cytokine therapy for treatment of inflammatory diseases, specifically rheumatoid arthritis (RA). It acts as a p38 MAP kinase inhibitor. In the future, VX-702 may be investigated for combination with methotrexate, a commonly used therapy for RA.
Investigational
Matched Iupac: … 2-(2,4-difluorophenyl)-6-[1-(2,6-difluorophenyl)carbamoylamino]pyridine-3-carboxamide …
Experimental
Matched Name: … 3-(1H-BENZIMIDAZOL-2-YL)-1H-INDAZOLE …
Matched Iupac: … 3-(1H-1,3-benzodiazol-2-yl)-1H-indazole …
Amonafide is a substance that is being studied in the treatment of cancer. It belongs to the families of drugs called topoisomerase inhibitors and intercalating agents.
Investigational
Matched Iupac: … 11-amino-3-[2-(dimethylamino)ethyl]-3-azatricyclo[7.3.1.0^{5,13}]trideca-1(13),5,7,9,11-pentaene-2,4- …
Experimental
Matched Name: … 2-(1H-pyrazol-3-yl)-1H-benzimidazole …
Matched Iupac: … 2-(1H-pyrazol-3-yl)-1H-1,3-benzodiazole …
9-(4-hydroxybutyl)-N2-phenylguanine is a solid. This compound belongs to the hypoxanthines. These are compounds containing the purine derivative 1H-purin-6(9H)-one. 9-(4-hydroxybutyl)-n2-phenylguanine is known to target thymidine kinase.
Experimental
Matched Iupac: … 9-(4-hydroxybutyl)-2-(phenylamino)-6,9-dihydro-1H-purin-6-one …
Matched Description: … These are compounds containing the purine derivative 1H-purin-6(9H)-one. 9-(4-hydroxybutyl)-n2-phenylguanine …
Isaralgagene civaparvovec, formerly known as ST-920, is liver-tropic rAAV 2/6 vector carrying the cDNA for human alpha-galactosidase A (α-Gal A) enzyme. It is developed by Sangamo Therapeutics and investigated in Fabry Disease.
Investigational
Matched Description: … Isaralgagene civaparvovec, formerly known as ST-920, is liver-tropic rAAV 2/6 vector carrying the cDNA …
Experimental
Matched Name: … 3-{3-[(DIMETHYLAMINO)METHYL]-1H-INDOL-7-YL}PROPAN-1-OL …
Matched Iupac: … 3-{3-[(dimethylamino)methyl]-1H-indol-7-yl}propan-1-ol …
Experimental
Matched Name: … 2-O-(4'-AMIDINOPHENYL)-5-O-(3''-AMIDINOPHENYL)-1,4:3,6-DIANHYDRO-D-SORBITOL …
Matched Iupac: … 4-{[(3S,3aR,6R,6aR)-6-(3-carbamimidoylphenoxy)-hexahydrofuro[3,2-b]furan-3-yl]oxy}benzene-1-carboximidamide …
Navitoclax has been used in trials studying the treatment and basic science of Solid Tumors, Non-Hodgkin's Lymphoma, EGFR Activating Mutation, Chronic Lymphoid Leukemia, and Hematological Malignancies, among others. Navitoclax is an orally bioavailable small molecule inhibitor of Bcl-2 family proteins. It is a substance being studied in the treatment of...
Investigational
Matched Synonyms: … -1-Enylmethyl]-Piperazin-1-Yl}-Benzoyl)-3-Trifluoromethanesulfonylbenzenesulfonamide ... (R)-4-(3-Morpholin-4-Yl-1-Phenylsulfanylmethyl-Propylamino)-N-(4-{4-[2-(4-Chlorophenyl)-5,5-Dimethylcyclohex …
Matched Iupac: … -4-yl)-1-(phenylsulfanyl)butan-2-yl]amino}-3-trifluoromethanesulfonylbenzenesulfonyl)benzamide ... 4-(4-{[2-(4-chlorophenyl)-5,5-dimethylcyclohex-1-en-1-yl]methyl}piperazin-1-yl)-N-(4-{[(2R)-4-(morpholin …
Investigational
Displaying drugs 4126 - 4150 of 10342 in total