Displaying drugs 4301 - 4325 of 9781 in total
Bevantolol
Bevantolol is a beta-1 adrenoceptor antagonist that has been shown to be as effective as other beta blockers for the treatment of angina pectoris and hypertension. Mechanism of Action Animal experiments confirm both agonist and antagonist effects on alpha-receptors, in addition to antagonist activity at beta-1 receptors.
Experimental
Matched Synonyms: … 1-((2-(3,4-dimethoxyphenyl)ethyl)amino)-3-(3-methylphenoxy)-2-propanol ... 1-(3,4-dimethoxyphenethylamino)-3-(m-tolyloxy)-2-propanol ... 1-(3,4-dimethoxyphenethylamino)-3-m-tolyloxy-propan-2-ol …
Matched Iupac: … 1-{[2-(3,4-dimethoxyphenyl)ethyl]amino}-3-(3-methylphenoxy)propan-2-ol …
Matched Description: … Bevantolol is a beta-1 adrenoceptor antagonist that has been shown to be as effective as other beta blockers ... both agonist and antagonist effects on alpha-receptors, in addition to antagonist activity at beta-1 …
Matched Categories: … Adrenergic alpha-1 Receptor Antagonists ... Adrenergic beta-1 Receptor Antagonists …
Matched Iupac: … 1-{[2-(3,4-dimethoxyphenyl)ethyl]amino}-3-(3-methylphenoxy)propan-2-ol …
Matched Description: … Bevantolol is a beta-1 adrenoceptor antagonist that has been shown to be as effective as other beta blockers ... both agonist and antagonist effects on alpha-receptors, in addition to antagonist activity at beta-1 …
Matched Categories: … Adrenergic alpha-1 Receptor Antagonists ... Adrenergic beta-1 Receptor Antagonists …
2-Hydroxyestradiol
2-Hydroxyestradiol is classified as an endogenous steroid, catechol estrogen, and metabolite of estradiol. It is also a positional isomer of estriol.
Experimental
Indium-111 Pentetreotide
Investigational
RUS 3108
RUS 3108 is being developed for the treatment of atherosclerosis, the major cause of cardiovascular disorders such as heart attacks and stroke by Dr. Reddy’s Laboratories.
The drug’s Phase I clinical trials have been initiated in Europe to assess safety of the drug compound in healthy volunteers.
Investigational
Matched Description: … The drug’s Phase I clinical trials have been initiated in Europe to assess safety of the drug compound …
Alphameprodine
Alphameprodine is an opioid analgesic classified by the United States Drug Enforcement Administration under Schedule I of illegal substances. The stereoisomer betameprodine is similarly classified, however alphameprodine is more widely used (both are referred to as Meprodine). Alphameprodine is a structural analogue of meperidine. It exerts physiological effects characteristic of...
Experimental
Illicit
Matched Synonyms: … alpha-3-ethyl-1-methyl-4-phenyl-4-propionoxypiperidine ... alpha-3-Ethyl-1-methyl-4-phenyl-4-propionyloxypiperidine ... 3alpha-Ethyl-1-methyl-4-phenyl-4alpha-piperidyl propionat …
Matched Iupac: … (3S,4R)-3-ethyl-1-methyl-4-phenylpiperidin-4-yl propanoate …
Matched Description: … an opioid analgesic classified by the United States Drug Enforcement Administration under Schedule I …
Matched Iupac: … (3S,4R)-3-ethyl-1-methyl-4-phenylpiperidin-4-yl propanoate …
Matched Description: … an opioid analgesic classified by the United States Drug Enforcement Administration under Schedule I …
3,4-dimethylaniline
Experimental
Matched Synonyms: … 1-amino-3,4-dimethylbenzene ... 3,4-dimethylbenzene-1-amine …
5-[1-(3,4-Dimethoxy-Benzoyl)-1,2,3,4-Tetrahydro-Quinolin-6-Yl]-6-Methyl-3,6-Dihydro-[1,3,4]Thiadiazin-2-One
Experimental
Matched Name: … 5-[1-(3,4-Dimethoxy-Benzoyl)-1,2,3,4-Tetrahydro-Quinolin-6-Yl]-6-Methyl-3,6-Dihydro-[1,3,4]Thiadiazin …
Matched Iupac: … (6R)-5-[1-(3,4-dimethoxybenzoyl)-1,2,3,4-tetrahydroquinolin-6-yl]-6-methyl-3,6-dihydro-2H-1,3,4-thiadiazin …
Matched Iupac: … (6R)-5-[1-(3,4-dimethoxybenzoyl)-1,2,3,4-tetrahydroquinolin-6-yl]-6-methyl-3,6-dihydro-2H-1,3,4-thiadiazin …
(1S,5S,7R)-N~7~-(BIPHENYL-4-YLMETHYL)-N~3~-HYDROXY-6,8-DIOXA-3-AZABICYCLO[3.2.1]OCTANE-3,7-DICARBOXAMIDE
Experimental
Matched Name: … (1S,5S,7R)-N~7~-(BIPHENYL-4-YLMETHYL)-N~3~-HYDROXY-6,8-DIOXA-3-AZABICYCLO[3.2.1]OCTANE-3,7-DICARBOXAMIDE …
Matched Iupac: … (1S,5S,7R)-N7-({[1,1'-biphenyl]-4-yl}methyl)-N3-hydroxy-6,8-dioxa-3-azabicyclo[3.2.1]octane-3,7-dicarboxamide …
Matched Iupac: … (1S,5S,7R)-N7-({[1,1'-biphenyl]-4-yl}methyl)-N3-hydroxy-6,8-dioxa-3-azabicyclo[3.2.1]octane-3,7-dicarboxamide …
1-Androstenedione
Experimental
Illicit
Matched Synonyms: … 5alpha-androst-1-ene-3,17-dione …
Matched Name: … 1-Androstenedione …
Matched Name: … 1-Androstenedione …
[2'-HYDROXY-3'-(1H-PYRROLO[3,2-C]PYRIDIN-2-YL)-BIPHENYL-3-YLMETHYL]-UREA
Experimental
Matched Name: … [2'-HYDROXY-3'-(1H-PYRROLO[3,2-C]PYRIDIN-2-YL)-BIPHENYL-3-YLMETHYL]-UREA …
Matched Iupac: … [(2'-hydroxy-3'-{1H-pyrrolo[3,2-c]pyridin-2-yl}-[1,1'-biphenyl]-3-yl)methyl]urea …
Matched Iupac: … [(2'-hydroxy-3'-{1H-pyrrolo[3,2-c]pyridin-2-yl}-[1,1'-biphenyl]-3-yl)methyl]urea …
ANC-501
ANC-501 is under investigation in clinical trial NCT05439603 (ANC-501 in the Treatment of Adults With Major Depressive Disorder).
Investigational
Matched Synonyms: … 3-(3-Chlorophenyl)-1,5-dihydro-N-(1-methylethyl)-1-[4-[2-(4-morpholinyl)ethyl]phenyl]-5-oxo-4H-1,2,4- …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
3-(1,10-Phenanthrol-2-Yl)-L-Alanine
Experimental
Matched Name: … 3-(1,10-Phenanthrol-2-Yl)-L-Alanine …
Matched Iupac: … (2S)-2-amino-3-(1,10-phenanthrolin-2-yl)propanoic acid …
Matched Iupac: … (2S)-2-amino-3-(1,10-phenanthrolin-2-yl)propanoic acid …
Inolimomab
Inolimomab is under investigation as an agent to treat steroid-resistant graft vs host disease. It has thus far offered similar efficacy to other monoclonal antibody options, though it may carry a higher risk of infections.
Investigational
4-[(1S,2S,5S,9R)-5-(HYDROXYMETHYL)-8,9-DIMETHYL-3-OXABICYCLO[3.3.1]NON-7-EN-2-YL]PHENOL
Experimental
Matched Name: … 4-[(1S,2S,5S,9R)-5-(HYDROXYMETHYL)-8,9-DIMETHYL-3-OXABICYCLO[3.3.1]NON-7-EN-2-YL]PHENOL …
Matched Iupac: … 4-[(1R,2S,5S,8S,9R)-5-(hydroxymethyl)-8,9-dimethyl-3-oxabicyclo[3.3.1]nonan-2-yl]phenol …
Matched Iupac: … 4-[(1R,2S,5S,8S,9R)-5-(hydroxymethyl)-8,9-dimethyl-3-oxabicyclo[3.3.1]nonan-2-yl]phenol …
4-[(1S,2S,5S)-5-(HYDROXYMETHYL)-6,8,9-TRIMETHYL-3-OXABICYCLO[3.3.1]NON-7-EN-2-YL]PHENOL
Experimental
Matched Name: … 4-[(1S,2S,5S)-5-(HYDROXYMETHYL)-6,8,9-TRIMETHYL-3-OXABICYCLO[3.3.1]NON-7-EN-2-YL]PHENOL …
Matched Iupac: … 4-[(1S,2S,5S,6S,9S)-5-(hydroxymethyl)-6,8,9-trimethyl-3-oxabicyclo[3.3.1]non-7-en-2-yl]phenol …
Matched Iupac: … 4-[(1S,2S,5S,6S,9S)-5-(hydroxymethyl)-6,8,9-trimethyl-3-oxabicyclo[3.3.1]non-7-en-2-yl]phenol …
3,4-Dihydroxy-1-Methylquinolin-2(1h)-One
Experimental
Matched Name: … 3,4-Dihydroxy-1-Methylquinolin-2(1h)-One …
Matched Iupac: … 3,4-dihydroxy-1-methyl-1,2-dihydroquinolin-2-one …
Matched Iupac: … 3,4-dihydroxy-1-methyl-1,2-dihydroquinolin-2-one …
ZK-93423
ZK-93423 is a beta-carboline with muscle relaxant activity with agonistic properties at the benzodiazepine receptor.
Investigational
Matched Synonyms: … 9H-Pyrido[3,4-b]indole-3-carboxylicacid, 4-(methoxymethyl)-6-(phenylmethoxy)-, ethyl ester …
Matched Iupac: … ethyl 6-(benzyloxy)-4-(methoxymethyl)-9H-pyrido[3,4-b]indole-3-carboxylate …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 3-Ring …
Matched Iupac: … ethyl 6-(benzyloxy)-4-(methoxymethyl)-9H-pyrido[3,4-b]indole-3-carboxylate …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 3-Ring …
Duvoglustat
An alpha-glucosidase inhibitor with antiviral action. Derivatives of deoxynojirimycin may have anti-HIV activity.
Investigational
Matched Synonyms: … 1 deoxynojirimycin ... 1-deoxynojirimycin ... 1-deoxy-nojirimycin …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Indole-3-Propanol Phosphate
Experimental
Matched Name: … Indole-3-Propanol Phosphate …
Matched Iupac: … [3-(1H-indol-3-yl)propoxy]phosphonic acid …
Matched Iupac: … [3-(1H-indol-3-yl)propoxy]phosphonic acid …
Indole-3-Glycerol Phosphate
Experimental
Matched Name: … Indole-3-Glycerol Phosphate …
Matched Iupac: … [(2R,3S)-2,3-dihydroxy-3-(1H-indol-3-yl)propoxy]phosphonic acid …
Matched Iupac: … [(2R,3S)-2,3-dihydroxy-3-(1H-indol-3-yl)propoxy]phosphonic acid …
5-(4-METHOXYBIPHENYL-3-YL)-1,2,5-THIADIAZOLIDIN-3-ONE 1,1-DIOXIDE
Experimental
Matched Name: … 5-(4-METHOXYBIPHENYL-3-YL)-1,2,5-THIADIAZOLIDIN-3-ONE 1,1-DIOXIDE …
Matched Iupac: … 5-{4-methoxy-[1,1'-biphenyl]-3-yl}-1lambda6,2,5-thiadiazolidine-1,1,3-trione …
Matched Iupac: … 5-{4-methoxy-[1,1'-biphenyl]-3-yl}-1lambda6,2,5-thiadiazolidine-1,1,3-trione …
Torcetrapib
Torcetrapib (CP-529414, Pfizer) was developed to treat hypercholesterolemia but its development was halted in 2006 when phase III studies showed excessive mortality in the treatment group receiving a combination of atorvastatin and the study drug.
Investigational
Matched Iupac: … trifluoromethyl)phenyl]methyl}(methoxycarbonyl)amino)-2-ethyl-6-(trifluoromethyl)-1,2,3,4-tetrahydroquinoline-1- …
Displaying drugs 4301 - 4325 of 9781 in total