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Displaying drugs 4601 - 4625 of 5498 in total

Ergometrine

An ergot alkaloid with uterine and vascular smooth muscle contractile properties.
Approved
Matched Synonyms: … D-lysergic acid-L-propanolamide ... D-lysergic acid 1-hydroxymethylethylamide ... (6aR,9R)-7-Methyl-4,6,6a,7,8,9-hexahydro-indolo[4,3-fg]quinoline-9-carboxylic acid ((S)-2-hydroxy-1-methyl-ethyl …
Matched Description: … An ergot alkaloid with uterine and vascular smooth muscle contractile properties. …
Matched Salts cas: … 129-51-1 …
Matched Mixtures name: … Syntometrine Injection 5IU/1ML Ampoule …
Matched Categories: … Ergot Alkaloids and Derivatives ... Genito Urinary System and Sex Hormones ... Adrenergic alpha-Agonists ... Adrenergic alpha-1 Receptor Agonists …

Efocipegtrutide

Efocipegtrutide is a long-acting, monomeric peptide triple agonist.
Investigational
Matched Synonyms: … GAMMA.4-CHAIN C REGION C-TERMINAL FRAGMENT), DIMER, 1-(1-(3-HYDROXYPROPYL)-L-PROLINE), 1-ETHER WITH .ALPHA …
Matched Description: … Efocipegtrutide is a long-acting, monomeric peptide triple agonist. …

Norclobazam

Investigational
Matched Synonyms: … 1h-1,5-benzodiazepine-2,4(3h,5h)-dione, 8-chloro-1-phenyl-7-chloro-5-phenyl-1,2,4,5-tetrahydro-3h-1,5 …

Sibutramine

Sibutramine (trade name Meridia in the USA, Reductil in Europe and other countries), usually as sibutramide hydrochloride monohydrate, is an orally administered agent for the treatment of obesity. It is a centrally acting stimulant chemically related to amphetamines thus it is classified as a Schedule IV controlled substance in the...
Approved
Illicit
Investigational
Withdrawn
Matched Description: … Sibutramine (trade name Meridia in the USA, Reductil in Europe and other countries), usually as sibutramide ... hydrochloride monohydrate, is an orally administered agent for the treatment of obesity. ... increases the risk of heart attack and stroke in patients with a history of heart disease. …
Matched Salts cas: … 125494-59-9 …
Matched Salts name: … Sibutramine hydrochloride …
Matched Categories: … Alimentary Tract and Metabolism ... Serotonin and Noradrenaline Reuptake Inhibitors ... Norepinephrine, Serotonin, and Dopamine Reuptake Inhibitor Anorectic ... Drugs that are Mainly Renally Excreted …
Matched Products: … OBESTOPPOR 5 MG CAPSULAS ... Apo-sibutramine ... MESURA-ABL 10 MG CAPSULAS …

Efzofitimod

Efzofitimod (ATYR1923) is a fusion protein comprised of the immuno-modulatory domain of histidyl tRNA synthetase fused to the FC region of a human antibody. It is a selective modulator of neuropilin-2 that downregulates the innate and adaptive immune response in inflammatory disease states.
Investigational
Matched Synonyms: … Human IgG1Fc- iMod domain (amino acids 2-60) of human HARS fusion protein …
Matched Description: … It is a selective modulator of neuropilin-2 that downregulates the innate and adaptive immune response ... synthetase fused to the FC region of a human antibody. ... Efzofitimod (ATYR1923) is a fusion protein comprised of the immuno-modulatory domain of histidyl tRNA …

(7as,12ar,12bs)-1,2,3,4,7a,12,12a,12b-Octahydroindolo[2,3-a]Quinolizin-7(6h)-One

Experimental
Matched Name: … (7as,12ar,12bs)-1,2,3,4,7a,12,12a,12b-Octahydroindolo[2,3-a]Quinolizin-7(6h)-One …
Matched Iupac: … (12bS)-1H,2H,3H,4H,6H,7H,12H,12bH-indolo[2,3-a]quinolizin-7-one …

N-cyclohexyl-4-imidazo[1,2-a]pyridin-3-yl-N-methylpyrimidin-2-amine

Experimental
Matched Name: … N-cyclohexyl-4-imidazo[1,2-a]pyridin-3-yl-N-methylpyrimidin-2-amine …
Matched Iupac: … N-cyclohexyl-4-{imidazo[1,2-a]pyridin-3-yl}-N-methylpyrimidin-2-amine …

6-(2-fluorophenyl)-N-(pyridin-3-ylmethyl)imidazo[1,2-a]pyrazin-8-amine

Experimental
Matched Name: … 6-(2-fluorophenyl)-N-(pyridin-3-ylmethyl)imidazo[1,2-a]pyrazin-8-amine …
Matched Iupac: … 6-(2-fluorophenyl)-N-[(pyridin-3-yl)methyl]imidazo[1,2-a]pyrazin-8-amine …

(2R,3R)-7-(methylsulfonyl)-3-(2,4,5-trifluorophenyl)-1,2,3,4-tetrahydropyrido[1,2-a]benzimidazol-2-amine

Experimental
Matched Name: … (2R,3R)-7-(methylsulfonyl)-3-(2,4,5-trifluorophenyl)-1,2,3,4-tetrahydropyrido[1,2-a]benzimidazol-2-amine …
Matched Iupac: … (11R,12R)-5-methanesulfonyl-11-(2,4,5-trifluorophenyl)-1,8-diazatricyclo[7.4.0.0^{2,7}]trideca-2,4,6,8 …

[(1-{2[(4-Carbamimidoyl-Phenylamino)-Methyl]-1-Methyl-1h-Benzoimidazol-5-Yl}-Cyclopropyl)-Pyridin-2-Yl-Methyleneaminooxy]-Acetic Acid Ethyl Ester

Experimental
Matched Name: … ]-Acetic Acid Ethyl Ester ... [(1-{2[(4-Carbamimidoyl-Phenylamino)-Methyl]-1-Methyl-1h-Benzoimidazol-5-Yl}-Cyclopropyl)-Pyridin-2-Yl-Methyleneaminooxy …
Matched Iupac: … ethyl 2-{[(E)-{[1-(2-{[(4-carbamimidoylphenyl)amino]methyl}-1-methyl-1H-1,3-benzodiazol-5-yl)cyclopropyl …

Fibroblast growth factor-1

Investigational
Matched Synonyms: … Acidic fibroblast growth factor ... Fibroblast growth factor, acidic ... Acidic fibroblast growth factor (aFGF) …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …

3-[3-chloro-5-(5-{[(1S)-1-phenylethyl]amino}isoxazolo[5,4-c]pyridin-3-yl)phenyl]propan-1-ol

Experimental
Matched Name: … 3-[3-chloro-5-(5-{[(1S)-1-phenylethyl]amino}isoxazolo[5,4-c]pyridin-3-yl)phenyl]propan-1-ol …
Matched Iupac: … 3-[3-chloro-5-(5-{[(1S)-1-phenylethyl]amino}-[1,2]oxazolo[5,4-c]pyridin-3-yl)phenyl]propan-1-ol …

2',3'-Dehydro-2',3'-Deoxy-Thymidine 5'-Diphosphate

Experimental
Matched Name: … 2',3'-Dehydro-2',3'-Deoxy-Thymidine 5'-Diphosphate …
Matched Iupac: … })phosphoryl]oxy}phosphonic acid ... {[hydroxy({[(2S,5R)-5-(5-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-2,5-dihydrofuran-2-yl]methoxy …

2,4-Diamino-5-(3,4,5-Trimethoxy-Benzyl)-Pyrimidin-1-Ium

Experimental
Matched Name: … 2,4-Diamino-5-(3,4,5-Trimethoxy-Benzyl)-Pyrimidin-1-Ium …
Matched Iupac: … 2,4-diamino-5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidin-1-ium …

5-Nitro-6-ribityl-amino-2,4(1H,3H)-pyrimidinedione

Experimental
Matched Name: … 5-Nitro-6-ribityl-amino-2,4(1H,3H)-pyrimidinedione …
Matched Iupac: … 5-nitro-6-{[(2S,3S,4R)-2,3,4,5-tetrahydroxypentyl]amino}-1,2,3,4-tetrahydropyrimidine-2,4-dione …

2-HYDROXY-5-{[(1E)-2-PHENYLETHYLIDENE]AMINO}-L-TYROSINE

Experimental
Matched Name: … 2-HYDROXY-5-{[(1E)-2-PHENYLETHYLIDENE]AMINO}-L-TYROSINE …
Matched Iupac: … (2S)-2-amino-3-{2,4-dihydroxy-5-[(E)-(2-phenylethylidene)amino]phenyl}propanoic acid …

5-HYDROXY-2-(4-HYDROXYPHENYL)-1-BENZOFURAN-7-CARBONITRILE

Experimental
Matched Name: … 5-HYDROXY-2-(4-HYDROXYPHENYL)-1-BENZOFURAN-7-CARBONITRILE …
Matched Iupac: … 5-hydroxy-2-(4-hydroxyphenyl)-1-benzofuran-7-carbonitrile …

3-ETHYL-2-(4-HYDROXYPHENYL)-2H-INDAZOL-5-OL

Experimental
Matched Name: … 3-ETHYL-2-(4-HYDROXYPHENYL)-2H-INDAZOL-5-OL …
Matched Iupac: … 3-ethyl-2-(4-hydroxyphenyl)-2H-indazol-5-ol …

5-(3-HYDROXYPHENYL)ISOTHIAZOL-3(2H)-ONE 1,1-DIOXIDE

Experimental
Matched Name: … 5-(3-HYDROXYPHENYL)ISOTHIAZOL-3(2H)-ONE 1,1-DIOXIDE …
Matched Iupac: … 5-(3-hydroxyphenyl)-2,3-dihydro-1lambda6,2-thiazole-1,1,3-trione …

(2-AMINO-1,3-OXAZOL-5-YL)-(3-BROMOPHENYL)METHANONE

Experimental
Matched Name: … (2-AMINO-1,3-OXAZOL-5-YL)-(3-BROMOPHENYL)METHANONE …
Matched Iupac: … 5-(3-bromobenzoyl)-1,3-oxazol-2-amine …

4-amino-7,7-dimethyl-7,8-dihydroquinazolin-5(6H)-one

Experimental
Matched Name: … 4-amino-7,7-dimethyl-7,8-dihydroquinazolin-5(6H)-one …
Matched Iupac: … 4-amino-7,7-dimethyl-5,6,7,8-tetrahydroquinazolin-5-one …

5-[(3R)-3-(5-methoxy-4'-methylbiphenyl-3-yl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine

Experimental
Matched Name: … 5-[(3R)-3-(5-methoxy-4'-methylbiphenyl-3-yl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine …
Matched Iupac: … 5-[(3R)-3-{5-methoxy-4'-methyl-[1,1'-biphenyl]-3-yl}but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine …

4-{5-[(Z)-(2-IMINO-4-OXO-1,3-THIAZOLIDIN-5-YLIDENE)METHYL]FURAN-2-YL}-2-(TRIFLUOROMETHYL)BENZENESULFONAMIDE

Experimental
Matched Name: … 4-{5-[(Z)-(2-IMINO-4-OXO-1,3-THIAZOLIDIN-5-YLIDENE)METHYL]FURAN-2-YL}-2-(TRIFLUOROMETHYL)BENZENESULFONAMIDE …
Matched Iupac: … 4-(5-{[(5Z)-2-imino-4-oxo-1,3-thiazolidin-5-ylidene]methyl}furan-2-yl)-2-(trifluoromethyl)benzene-1-sulfonamide …

TH-9402 free base

Investigational
Matched Synonyms: … Benzoic acid, 2-(6-amino-4,5-dibromo-3-imino-3h-xanthen-9-yl)-, methyl ester …

Osimertinib

Osimertinib is an oral, third-generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) drug developed by AstraZeneca Pharmaceuticals.[A7926,L43453] Its use is indicated for the treatment of metastatic non-small cell lung cancer (NSCLC) in cases where tumour EGFR expression is positive for the T790M mutation as detected by FDA-approved testing...
Approved
Matched Synonyms: … N-(2-{[2-(dimethylamino)ethyl](methyl)amino}-4-methoxy-5-{[4-(1-methyl-1H-indol-3-yl)pyrimidin-2-yl]amino …
Matched Iupac: … N-(2-{[2-(dimethylamino)ethyl](methyl)amino}-4-methoxy-5-{[4-(1-methyl-1H-indol-3-yl)pyrimidin-2-yl]amino …
Matched Description: … ATP binding activity to EGFR and result in poor prognosis for late-stage disease. ... detected by FDA-approved testing and which has progressed following therapy with a first-generation ... Approximately 10% of patients with NSCLC have a rapid and clinically effective response to EGFR-TKIs …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Acids, Acyclic ... Carboxylic Acids ... P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Displaying drugs 4601 - 4625 of 5498 in total