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Displaying drugs 4676 - 4700 of 5429 in total

7-HYDROXY-4-METHYL-3-(2-HYDROXY-ETHYL)COUMARIN

Experimental
Matched Name: … 7-HYDROXY-4-METHYL-3-(2-HYDROXY-ETHYL)COUMARIN …
Matched Iupac: … 7-hydroxy-3-(2-hydroxyethyl)-4-methyl-2H-chromen-2-one …

Olezarsen

Olezarsen is an antisense oligonucleotide targeting messenger RNA for apolipoprotein C-III (APOC3).
Investigational
Matched Synonyms: … 2'-O-(2-METHOXYETHYL)-P-THIOADENYLYL-(3'-O->5'-O)-2'-O-(2-METHOXYETHYL)-P-THIOGUANYLYL-(3 ... ALL-P-AMBO-5'-O-(((6-(5-((TRIS(3-(6-(2-ACETAMIDO-2-DEOXY-.BETA. ... -D-GALACTOPYRANOSYLOXY)HEXYLAMINO)-3-OXOPROPOXYMETHYL))METHYL)AMINO-5-OXOPENTANAMIDO)HEXYL))PHOSPHO)- …
Matched Description: … Olezarsen is an antisense oligonucleotide targeting messenger RNA for apolipoprotein C-III (APOC3). …

Danicopan

Paroxysmal nocturnal hemoglobinuria (PNH) is a rare acquired hematologic disease characterized by hemolysis, thrombophilia, and bone marrow dysfunction.[A263501,L50417] Both hemolysis and thrombophilia are mediated primarily by the complement system. Standard therapy for PNH involves the use of complement C5 inhibitors (e.g. eculizumab, ravulizumab) which are effective in mitigating complement-mediated intravascular...
Approved
Investigational
Matched Synonyms: … (2S,4R)-1-(2-(3-acetyl-5-(2-methylpyrimidine-5-yl)-1H-indazol-1-yl)acetyl)-N-(6-bromopyridine-2-yl)-4 ... (2S,4R)-1-(2-(3-acetyl-5-(2-methylpyrimidin-5-yl)-1H-indazol-1-yl)acetyl)-N-(6-bromopyridin-2-yl)-4-fluoropyrrolidine …
Matched Iupac: … (2S,4R)-1-{2-[3-acetyl-5-(2-methylpyrimidin-5-yl)-1H-indazol-1-yl]acetyl}-N-(6-bromopyridin-2-yl)-4-fluoropyrrolidine …
Matched Description: … hemoglobinuria (PNH) is a rare acquired hematologic disease characterized by hemolysis, thrombophilia, and ... [A263501,L50417] Both hemolysis and thrombophilia are mediated primarily by the complement system. ... eculizumab], [ravulizumab]) which are effective in mitigating complement-mediated intravascular hemolysis and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Imino Acids ... Amino Acids, Cyclic ... Antineoplastic and Immunomodulating Agents …

Valrubicin

Valrubicin (N-trifluoroacetyladriamycin-14-valerate) is a chemotherapy drug commonly marketed under the trade name VALSTAR. It is a semisynthetic analog of the doxorubicin, which is an anthracycline drug. Used in the treatment of the bladder cancer, valrubicin is administered by direct infusion into the bladder.
Approved
Matched Synonyms: … 2-oxo-2-[(2S,4S)-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-4-({2,3,6-trideoxy-3-[(trifluoroacetyl)amino] ... (8S, 10S)-8-glycoloyl-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-10-[[2,3,6-trideoxy-3-(2,2,2-trifluoroacetamido …
Matched Categories: … Anthracyclines and Related Substances ... Antineoplastic and Immunomodulating Agents ... Cytotoxic Antibiotics and Related Substances …

N(6)-dimethylallyladenine

Experimental
Matched Synonyms: … N6-(3-methylbut-2-enyl)adenine …
Matched Iupac: … N-(3-methylbut-2-en-1-yl)-9H-purin-6-amine …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …

Entacapone

Entacapone is a selective, reversible catechol-O-methyl transferase (COMT) inhibitor for the treatment of Parkinson's disease. It is a member of the class of nitrocatechols. When administered concomittantly with levodopa and a decarboxylase inhibitor (e.g., carbidopa), increased and more sustained plasma levodopa concentrations are reached as compared to the administration of...
Approved
Investigational
Matched Synonyms: … N,N-diethyl-2-cyano-3-(3,4-dihydroxy-5-nitrophenyl) acrylamide ... (E)-alpha-Cyano-N,N-diethyl-3,4-dihydroxy-5-nitrocinnamamide …
Matched Iupac: … (2E)-2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N,N-diethylprop-2-enamide …
Matched Description: … Entacapone is a selective, reversible catechol-O-methyl transferase (COMT) inhibitor for the treatment ... and a decarboxylase inhibitor. ... When administered concomittantly with levodopa and a decarboxylase inhibitor (e.g., carbidopa), increased …
Matched Mixtures name: … Carbidopa, Levodopa and Entacapone ... Carbidopa, Levodopa and Entacapone ... Carbidopa, Levodopa and Entacapone …

Prasterone

Prasterone, also known as dehydroepiandrosterone (DHEA) is a major C19 steroid produced by the adrenal cortex. It is also produced in small quantities in the testis and the ovary. Dehydroepiandrosterone (DHEA) can be converted to testosterone; androstenedione; estradiol; and estrone. Most of DHEA is sulfated (dehydroepiandrosterone sulfate) before secretion. In...
Approved
Investigational
Nutraceutical
Matched Synonyms: … 3β-hydroxyandrost-5-en-17-one ... 3-beta-hydroxy-5-androsten-17-one …
Matched Iupac: … (3aS,3bR,7S,9aR,9bS,11aS)-7-hydroxy-9a,11a-dimethyl-1H,2H,3H,3aH,3bH,4H,6H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta …
Matched Description: … Most of DHEA is sulfated (dehydroepiandrosterone sulfate) before secretion. ... In the United States, DHEA or DHEAS have been advertised with claims that they may be beneficial for ... It is also produced in small quantities in the testis and the ovary. …
Matched Categories: … Anabolic Agents for Systemic Use ... Alimentary Tract and Metabolism ... Androgens and Estrogens ... prasterone and estrogen ... Genito Urinary System and Sex Hormones …

4-(2,5-Dichloro-Thiophen-3-Yl)-Pyrimidin-2-Ylamine

Experimental
Matched Name: … 4-(2,5-Dichloro-Thiophen-3-Yl)-Pyrimidin-2-Ylamine …
Matched Iupac: … 4-(2,5-dichlorothiophen-3-yl)pyrimidin-2-amine …

5-Methoxy-1,2-Dimethyl-3-(Phenoxymethyl)Indole-4,7-Dione

Experimental
Matched Name: … 5-Methoxy-1,2-Dimethyl-3-(Phenoxymethyl)Indole-4,7-Dione …
Matched Iupac: … 5-methoxy-1,2-dimethyl-3-(phenoxymethyl)-4,7-dihydro-1H-indole-4,7-dione …

1-Hydroxy-2-S-glutathionyl-3-para-nitrophenoxy-propane

Experimental
Matched Name: … 1-Hydroxy-2-S-glutathionyl-3-para-nitrophenoxy-propane …
Matched Iupac: … }ethyl]carbamoyl}butanoic acid ... (2S)-2-amino-4-{[(1R)-1-[(carboxymethyl)carbamoyl]-2-{[(2S)-1-hydroxy-3-(4-nitrophenoxy)propan-2-yl]sulfanyl …

N-ethyl-N-[3-(propylamino)propyl]propane-1,3-diamine

Experimental
Matched Name: … N-ethyl-N-[3-(propylamino)propyl]propane-1,3-diamine …
Matched Iupac: … ethyl(3-{[3-(propylamino)propyl]amino}propyl)amine …

N-phenyl-1H-pyrrolo[2,3-b]pyridin-3-amine

Experimental
Matched Name: … N-phenyl-1H-pyrrolo[2,3-b]pyridin-3-amine …
Matched Iupac: … N-phenyl-1H-pyrrolo[2,3-b]pyridin-3-amine …

5-[(1S)-1-(3-chlorophenyl)ethoxy]quinazoline-2,4-diamine

Experimental
Matched Name: … 5-[(1S)-1-(3-chlorophenyl)ethoxy]quinazoline-2,4-diamine …
Matched Iupac: … 5-[(1S)-1-(3-chlorophenyl)ethoxy]quinazoline-2,4-diamine …

(3R)-3-(FLUOROMETHYL)-7-(THIOMORPHOLIN-4-YLSULFONYL)-1,2,3,4-TETRAHYDROISOQUINOLINE

Experimental
Matched Name: … (3R)-3-(FLUOROMETHYL)-7-(THIOMORPHOLIN-4-YLSULFONYL)-1,2,3,4-TETRAHYDROISOQUINOLINE …
Matched Iupac: … (3R)-3-(fluoromethyl)-7-(thiomorpholine-4-sulfonyl)-1,2,3,4-tetrahydroisoquinoline …

4-[3-(4-CHLOROPHENYL)-1H-PYRAZOL-5-YL]PIPERIDINE

Experimental
Matched Name: … 4-[3-(4-CHLOROPHENYL)-1H-PYRAZOL-5-YL]PIPERIDINE …
Matched Iupac: … 4-[3-(4-chlorophenyl)-1H-pyrazol-5-yl]piperidine …

1-BENZYL-3-(4-METHOXYPHENYLAMINO)-4-PHENYLPYRROLE-2,5-DIONE

Experimental
Matched Name: … 1-BENZYL-3-(4-METHOXYPHENYLAMINO)-4-PHENYLPYRROLE-2,5-DIONE …
Matched Iupac: … 1-benzyl-3-[(4-methoxyphenyl)amino]-4-phenyl-2,5-dihydro-1H-pyrrole-2,5-dione …

1-(9-ethyl-9H-carbazol-3-yl)-N-methylmethanamine

Experimental
Matched Name: … 1-(9-ethyl-9H-carbazol-3-yl)-N-methylmethanamine …
Matched Iupac: … [(9-ethyl-9H-carbazol-3-yl)methyl](methyl)amine …

3(S)-AMINO-4-PHENYL-BUTAN-2(S)-OL

Experimental
Matched Name: … 3(S)-AMINO-4-PHENYL-BUTAN-2(S)-OL …
Matched Iupac: … (2S,3S)-3-amino-4-phenylbutan-2-ol …

2-[(2',3',4'-TRIFLUOROBIPHENYL-2-YL)OXY]ETHANOL

Experimental
Matched Name: … 2-[(2',3',4'-TRIFLUOROBIPHENYL-2-YL)OXY]ETHANOL …
Matched Iupac: … 2-({2',3',4'-trifluoro-[1,1'-biphenyl]-2-yl}oxy)ethan-1-ol …

(1S)-1-AMINO-2-(1H-INDOL-3-YL)ETHANOL

Experimental
Matched Name: … (1S)-1-AMINO-2-(1H-INDOL-3-YL)ETHANOL …
Matched Iupac: … (1S)-1-amino-2-(1H-indol-3-yl)ethan-1-ol …

3-{[(5R,6R)-5-Benzyl-6-hydroxy-2,4-bis(4-hydroxybenzyl)-3-oxo-1,2,4-triazepan-1-yl]sulfonyl}benzonitril

Experimental
Matched Name: … 3-{[(5R,6R)-5-Benzyl-6-hydroxy-2,4-bis(4-hydroxybenzyl)-3-oxo-1,2,4-triazepan-1-yl]sulfonyl}benzonitril …
Matched Iupac: … 3-{[(5R,6R)-5-benzyl-6-hydroxy-2,4-bis[(4-hydroxyphenyl)methyl]-3-oxo-1,2,4-triazepan-1-yl]sulfonyl}benzonitrile …

(2S,3S)-3-{3-[4-(METHYLSULFONYL)PHENYL]-1,2,4-OXADIAZOL-5-YL}-1-OXO-1-PYRROLIDIN-1-YLBUTAN-2-AMINE

Experimental
Matched Name: … (2S,3S)-3-{3-[4-(METHYLSULFONYL)PHENYL]-1,2,4-OXADIAZOL-5-YL}-1-OXO-1-PYRROLIDIN-1-YLBUTAN-2-AMINE …
Matched Iupac: … (2S,3S)-2-amino-3-[3-(4-methanesulfonylphenyl)-1,2,4-oxadiazol-5-yl]-1-(pyrrolidin-1-yl)butan-1-one …

(3,4,8b-Trimethyl-3-oxido-2,3a-dihydro-1H-pyrrolo[2,3-b]indol-3-ium-7-yl) N-(2-ethylphenyl)carbamate

Experimental
Matched Name: … (3,4,8b-Trimethyl-3-oxido-2,3a-dihydro-1H-pyrrolo[2,3-b]indol-3-ium-7-yl) N-(2-ethylphenyl)carbamate …
Matched Iupac: … 5-{[(2-ethylphenyl)carbamoyl]oxy}-1,3a,8-trimethyl-1H,2H,3H,3aH,8H,8aH-pyrrolo[2,3-b]indol-1-ium-1-olate …

(5-Hydroxy-6-methyl-4-{[(E)-(3-oxo-1,2-oxazolidin-4-ylidene)amino]methyl}-3-pyridinyl)methyl dihydrogen phosphate

Experimental
Matched Name: … (5-Hydroxy-6-methyl-4-{[(E)-(3-oxo-1,2-oxazolidin-4-ylidene)amino]methyl}-3-pyridinyl)methyl dihydrogen …
Matched Iupac: … acid ... {[5-hydroxy-6-methyl-4-({[(4E)-3-oxo-1,2-oxazolidin-4-ylidene]amino}methyl)pyridin-3-yl]methoxy}phosphonic …

(1S)-2-(1H-INDOL-3-YL)-1-[({5-[(E)-2-PYRIDIN-4-YLVINYL]PYRIDIN-3-YL}OXY)METHYL]ETHYLAMINE

Experimental
Matched Name: … (1S)-2-(1H-INDOL-3-YL)-1-[({5-[(E)-2-PYRIDIN-4-YLVINYL]PYRIDIN-3-YL}OXY)METHYL]ETHYLAMINE …
Matched Iupac: … (2S)-1-(1H-indol-3-yl)-3-({5-[(1E)-2-(pyridin-4-yl)ethenyl]pyridin-3-yl}oxy)propan-2-amine …
Displaying drugs 4676 - 4700 of 5429 in total