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Displaying drugs 4926 - 4950 of 15263 in total

CSL324

CSL324 is a fully human anti-G-CSFR antibody shown to have the ability to control G-CSF-mediated neutrophilia in cynomolgus macaques. It has potential applications in various inflammatory conditions such as cystic fibrosis, inflammatory bowel disease, rheumatoid arthritis, and vasculitis.
Investigational
Matched Description: … inflammatory conditions such as cystic fibrosis, inflammatory bowel disease, rheumatoid arthritis, and …

ADXS-31164

Investigational

ARO-APOC3

ARO-APOC3 is an investigational RNAi therapeutic targeting apolipoprotein C-III (APOC3). It received an Orphan Drug designation by the FDA for the treatment of familial chylomicronemia syndrome.
Investigational

SPG302

Investigational

AAV-CNGB3

AAV-CNGB3 is an adenovirus associated viral vector serotype 8 containing the human CNGB3 gene.
Investigational

5-(3,3-Dihydroxypropeny)-3-Methoxy-Benzene-1,2-Diol

Experimental
Matched Name: … 5-(3,3-Dihydroxypropeny)-3-Methoxy-Benzene-1,2-Diol …
Matched Iupac: … 5-[(1E)-3,3-dihydroxyprop-1-en-1-yl]-3-methoxybenzene-1,2-diol …

AZD-2066

AZD2066 has been used in trials studying the treatment and basic science of Pain, Chronic Pain, Reflux Episodes, Neuropathic Pain, and Diabetic Neuropathy, among others.
Investigational
Matched Iupac: … 4-{5-[(1R)-1-[5-(3-chlorophenyl)-1,2-oxazol-3-yl]ethoxy]-4-methyl-4H-1,2,4-triazol-3-yl}pyridine …
Matched Description: … Episodes, Neuropathic Pain, and Diabetic Neuropathy, among others. ... AZD2066 has been used in trials studying the treatment and basic science of Pain, Chronic Pain, Reflux …

CMX-2043

CMX-2043 has been used in trials studying the treatment and prevention of Non STEMI, Unstable Angina, Stable Coronary Artery Disease, and Percutaneous Coronary Intervention.
Investigational
Matched Iupac: … (4S)-4-{[(1S)-1-carboxyethyl]carbamoyl}-4-{5-[(3R)-1,2-dithiolan-3-yl]pentanamido}butanoic acid …
Matched Description: … Stable Coronary Artery Disease, and Percutaneous Coronary Intervention. ... CMX-2043 has been used in trials studying the treatment and prevention of Non STEMI, Unstable Angina, …
Matched Categories: … Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins …

SCB-2019

SCB-2019 is a recombinant trimeric S protein subunit vaccine candidate being investigated against COVID-19. This vaccine candidate resembles the native trimeric viral spike and is produced through mammalian cell-culture. The vaccine was developed and tested by Clover Biopharmaceuticals AUS Pty Ltd.. As of June 2020, the company is pursuing a...
Investigational
Matched Description: … The vaccine was developed and tested by Clover Biopharmaceuticals AUS Pty Ltd.. ... This vaccine candidate resembles the native trimeric viral spike and is produced through mammalian cell-culture ... company is pursuing a randomized, double blind, placebo controlled study (NCT04405908) to test the safety and …

XMT-2056

XMT-2056 is a HER2-targeted antibody-drug conjugate (ADC) consisting of a HER2-targeted antibody conjugated with a stimulator of interferon genes (STING) agonist payload.
Investigational

2-CHLORO-N-[(3R)-2-OXO-1,2,3,4-TETRAHYDROQUINOLIN-3-YL]-6H-THIENO[2,3-B]PYRROLE-5-CARBOXAMIDE

Experimental
Matched Name: … 2-CHLORO-N-[(3R)-2-OXO-1,2,3,4-TETRAHYDROQUINOLIN-3-YL]-6H-THIENO[2,3-B]PYRROLE-5-CARBOXAMIDE …
Matched Iupac: … 2-chloro-N-[(3R)-2-oxo-1,2,3,4-tetrahydroquinolin-3-yl]-6H-thieno[2,3-b]pyrrole-5-carboxamide …

(3Z)-6-(4-HYDROXY-3-METHOXYPHENYL)-3-(1H-PYRROL-2-YLMETHYLENE)-1,3-DIHYDRO-2H-INDOL-2-ONE

Experimental
Matched Name: … (3Z)-6-(4-HYDROXY-3-METHOXYPHENYL)-3-(1H-PYRROL-2-YLMETHYLENE)-1,3-DIHYDRO-2H-INDOL-2-ONE …
Matched Iupac: … (3Z)-6-(4-hydroxy-3-methoxyphenyl)-3-[(1H-pyrrol-2-yl)methylidene]-2,3-dihydro-1H-indol-2-one …

Levomethadone

Experimental
Matched Iupac: … (6R)-6-(dimethylamino)-4,4-diphenylheptan-3-one …
Matched Products: … L-Polamidon 20 mg Tabletten ... Levo-Methasan 20 mg-Tabletten …

(2S)-N-[(3E)-5-Cyclopropyl-3H-pyrazol-3-ylidene]-2-[4-(2-oxo-1-imidazolidinyl)phenyl]propanamide

Experimental
Matched Name: … (2S)-N-[(3E)-5-Cyclopropyl-3H-pyrazol-3-ylidene]-2-[4-(2-oxo-1-imidazolidinyl)phenyl]propanamide …
Matched Iupac: … (2S)-N-[(3E)-5-cyclopropyl-3H-pyrazol-3-ylidene]-2-[4-(2-oxoimidazolidin-1-yl)phenyl]propanamide …

(3Z)-1-[(6-fluoro-4H-1,3-benzodioxin-8-yl)methyl]-4-[(E)-2-phenylethenyl]-1H-indole-2,3-dione 3-oxime

Experimental
Matched Name: … (3Z)-1-[(6-fluoro-4H-1,3-benzodioxin-8-yl)methyl]-4-[(E)-2-phenylethenyl]-1H-indole-2,3-dione 3-oxime …
Matched Iupac: … (3Z)-1-[(6-fluoro-2,4-dihydro-1,3-benzodioxin-8-yl)methyl]-3-(hydroxyimino)-4-[(1E)-2-phenylethenyl]- …

3-Tyrosine

Experimental
Matched Synonyms: … 3-Hydroxyphenylalanine ... 3-(m-Hydroxyphenyl)alanine ... 3-Hydroxy-L-phenylalanine …
Matched Name: … 3-Tyrosine …
Matched Iupac: … (2S)-2-amino-3-(3-hydroxyphenyl)propanoic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins …

ZYC300

ZYC300 is a plasmid DNA of CYP1B1 encapsulated in biodegradable poly-DL-lactide-coglycolide microparticles. It is designed as a vaccine, intended to increase immune system sensitivity to CYP1B1, an enzyme highly prevalent in tumor cells.
Investigational

IGN311

IGN311 is a humanized monoclonal antibody (mab) against the Lewis Y carbohydrate antigen, a blood-group-related oligosaccharide.
Investigational
Matched Categories: … Amino Acids, Peptides, and Proteins …

PSN357

PSN357 is a glycogen phosphorylase inhibitor (GPI), which is designed to rapidly lower blood glucose levels by preventing glycogen breakdown to glucose in the liver.
Investigational

GSK-376501

GSK376501 has been used in trials studying the treatment and diagnostic of Type 2 Diabetes Mellitus.
Investigational
Matched Iupac: … 1-{[3,5-bis(2-methoxyethoxy)phenyl]methyl}-3-(4-tert-butylphenyl)-1H-indole-2-carboxylic acid …
Matched Description: … GSK376501 has been used in trials studying the treatment and diagnostic of Type 2 Diabetes Mellitus. …

GSK-364735

GSK-364735 (Naphthyridinone) has been used in trials studying the treatment of HIV-1 Infection and Infection, Human Immunodeficiency Virus.
Investigational
Matched Iupac: … -[(4-fluorophenyl)methyl]-4-hydroxy-N-(2-hydroxyethyl)-1-methyl-2-oxo-1,2-dihydro-1,5-naphthyridine-3- …
Matched Description: … GSK-364735 (Naphthyridinone) has been used in trials studying the treatment of HIV-1 Infection and Infection …

LY-3200882

LY-3200882 is under investigation in clinical trial NCT04158700 (A Study of LY3200882 and Pembrolizumab in Participants With Advanced Cancer).
Investigational
Matched Iupac: … 2-{4-[(4-{[1-cyclopropyl-3-(oxan-4-yl)-1H-pyrazol-4-yl]oxy}pyridin-2-yl)amino]pyridin-2-yl}propan-2-ol …
Matched Description: … LY-3200882 is under investigation in clinical trial NCT04158700 (A Study of LY3200882 and Pembrolizumab …

PACAP38

Experimental
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …

Ad-ISF35

Investigational

GYM329

GYM329 is a recombinant humanized IgG1-based monoclonal antibody which binds to human latent myostatin in a pH-dependent manner
Investigational
Displaying drugs 4926 - 4950 of 15263 in total