Displaying drugs 5101 - 5125 of 5749 in total
Valrubicin
Valrubicin (N-trifluoroacetyladriamycin-14-valerate) is a chemotherapy drug commonly marketed under the trade name VALSTAR. It is a semisynthetic analog of the doxorubicin, which is an anthracycline drug. Used in the treatment of the bladder cancer, valrubicin is administered by direct infusion into the bladder.
Approved
Matched Synonyms: … 2-oxo-2-[(2S,4S)-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-4-({2,3,6-trideoxy-3-[(trifluoroacetyl)amino] ... (8S, 10S)-8-glycoloyl-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-10-[[2,3,6-trideoxy-3-(2,2,2-trifluoroacetamido …
Matched Categories: … Anthracyclines and Related Substances ... Antineoplastic and Immunomodulating Agents ... Cytotoxic Antibiotics and Related Substances …
Matched Categories: … Anthracyclines and Related Substances ... Antineoplastic and Immunomodulating Agents ... Cytotoxic Antibiotics and Related Substances …
9-Butyl-8-(3-Methoxybenzyl)-9h-Purin-6-Amine
Experimental
Matched Name: … 9-Butyl-8-(3-Methoxybenzyl)-9h-Purin-6-Amine …
Matched Iupac: … 9-butyl-8-[(3-methoxyphenyl)methyl]-9H-purin-6-amine …
Matched Iupac: … 9-butyl-8-[(3-methoxyphenyl)methyl]-9H-purin-6-amine …
(4R)-4-(3-butoxy-4-methoxybenzyl)imidazolidin-2-one
Experimental
Matched Name: … (4R)-4-(3-butoxy-4-methoxybenzyl)imidazolidin-2-one …
Matched Iupac: … (4R)-4-[(3-butoxy-4-methoxyphenyl)methyl]imidazolidin-2-one …
Matched Iupac: … (4R)-4-[(3-butoxy-4-methoxyphenyl)methyl]imidazolidin-2-one …
N-[(4-HYDROXY-8-IODOISOQUINOLIN-3-YL)CARBONYL]GLYCINE
Experimental
Matched Name: … N-[(4-HYDROXY-8-IODOISOQUINOLIN-3-YL)CARBONYL]GLYCINE …
Matched Iupac: … 2-[(4-hydroxy-8-iodoisoquinolin-3-yl)formamido]acetic acid …
Matched Iupac: … 2-[(4-hydroxy-8-iodoisoquinolin-3-yl)formamido]acetic acid …
6-(3-BROMO-2-NAPHTHYL)-1,3,5-TRIAZINE-2,4-DIAMINE
Experimental
Matched Name: … 6-(3-BROMO-2-NAPHTHYL)-1,3,5-TRIAZINE-2,4-DIAMINE …
Matched Iupac: … 6-(3-bromonaphthalen-2-yl)-1,3,5-triazine-2,4-diamine …
Matched Iupac: … 6-(3-bromonaphthalen-2-yl)-1,3,5-triazine-2,4-diamine …
3-{[(4-methylphenyl)sulfonyl]amino}propyl pyridin-4-ylcarbamate
Experimental
Matched Name: … 3-{[(4-methylphenyl)sulfonyl]amino}propyl pyridin-4-ylcarbamate …
Matched Iupac: … 3-(4-methylbenzenesulfonamido)propyl N-(pyridin-4-yl)carbamate …
Matched Iupac: … 3-(4-methylbenzenesulfonamido)propyl N-(pyridin-4-yl)carbamate …
3-ETHYL-2-(4-HYDROXYPHENYL)-2H-INDAZOL-5-OL
Experimental
Matched Name: … 3-ETHYL-2-(4-HYDROXYPHENYL)-2H-INDAZOL-5-OL …
Matched Iupac: … 3-ethyl-2-(4-hydroxyphenyl)-2H-indazol-5-ol …
Matched Iupac: … 3-ethyl-2-(4-hydroxyphenyl)-2H-indazol-5-ol …
6-CHLORO-4-(CYCLOHEXYLOXY)-3-PROPYLQUINOLIN-2(1H)-ONE
Experimental
Matched Name: … 6-CHLORO-4-(CYCLOHEXYLOXY)-3-PROPYLQUINOLIN-2(1H)-ONE …
Matched Iupac: … 6-chloro-4-(cyclohexyloxy)-3-propyl-1,2-dihydroquinolin-2-one …
Matched Iupac: … 6-chloro-4-(cyclohexyloxy)-3-propyl-1,2-dihydroquinolin-2-one …
6-CHLORO-4-(CYCLOHEXYLSULFANYL)-3-PROPYLQUINOLIN-2(1H)-ONE
Experimental
Matched Name: … 6-CHLORO-4-(CYCLOHEXYLSULFANYL)-3-PROPYLQUINOLIN-2(1H)-ONE …
Matched Iupac: … 6-chloro-4-(cyclohexylsulfanyl)-3-propyl-1,2-dihydroquinolin-2-one …
Matched Iupac: … 6-chloro-4-(cyclohexylsulfanyl)-3-propyl-1,2-dihydroquinolin-2-one …
6-CHLORO-4-(CYCLOHEXYLOXY)-3-ISOPROPYLQUINOLIN-2(1H)-ONE
Experimental
Matched Name: … 6-CHLORO-4-(CYCLOHEXYLOXY)-3-ISOPROPYLQUINOLIN-2(1H)-ONE …
Matched Iupac: … 6-chloro-4-(cyclohexyloxy)-3-(propan-2-yl)-1,2-dihydroquinolin-2-one …
Matched Iupac: … 6-chloro-4-(cyclohexyloxy)-3-(propan-2-yl)-1,2-dihydroquinolin-2-one …
[[CYCLOHEXANESULFONYL-GLYCYL]-3[PYRIDIN-4-YL-AMINOMETHYL]ALANYL]PIPERIDINE
Experimental
Matched Name: … [[CYCLOHEXANESULFONYL-GLYCYL]-3[PYRIDIN-4-YL-AMINOMETHYL]ALANYL]PIPERIDINE …
Matched Iupac: … 4-{[(3R)-3-(2-cyclohexanesulfonamidoacetamido)-4-oxo-4-(piperidin-1-yl)butyl]amino}pyridin-1-ium …
Matched Iupac: … 4-{[(3R)-3-(2-cyclohexanesulfonamidoacetamido)-4-oxo-4-(piperidin-1-yl)butyl]amino}pyridin-1-ium …
4-(acetylamino)-N-(4-fluorophenyl)-1H-pyrazole-3-carboxamide
Experimental
Matched Name: … 4-(acetylamino)-N-(4-fluorophenyl)-1H-pyrazole-3-carboxamide …
Matched Iupac: … 4-acetamido-N-(4-fluorophenyl)-1H-pyrazole-3-carboxamide …
Matched Iupac: … 4-acetamido-N-(4-fluorophenyl)-1H-pyrazole-3-carboxamide …
(2-AMINO-1,3-OXAZOL-5-YL)-(3-BROMOPHENYL)METHANONE
Experimental
Matched Name: … (2-AMINO-1,3-OXAZOL-5-YL)-(3-BROMOPHENYL)METHANONE …
Matched Iupac: … 5-(3-bromobenzoyl)-1,3-oxazol-2-amine …
Matched Iupac: … 5-(3-bromobenzoyl)-1,3-oxazol-2-amine …
1-(3-bromophenyl)-7-chloro-6-methoxy-3,4-dihydroisoquinoline
1-(3-bromophenyl)-7-chloro-6-methoxy-3,4-dihydroisoquinoline is a solid. This compound belongs to the isoquinolines and derivatives. These are aromatic polycyclic compounds containing an isoquinoline moiety, which consists of a benzene ring fused to a pyridine ring and forming benzo[c]pyridine. This medication is known to target mitogen-activated protein kinase 10.
Experimental
Matched Name: … 1-(3-bromophenyl)-7-chloro-6-methoxy-3,4-dihydroisoquinoline …
Matched Iupac: … 1-(3-bromophenyl)-7-chloro-6-methoxy-3,4-dihydroisoquinoline …
Matched Description: … ring and forming benzo[c]pyridine. ... This compound belongs to the isoquinolines and derivatives. ... 1-(3-bromophenyl)-7-chloro-6-methoxy-3,4-dihydroisoquinoline is a solid. …
Matched Iupac: … 1-(3-bromophenyl)-7-chloro-6-methoxy-3,4-dihydroisoquinoline …
Matched Description: … ring and forming benzo[c]pyridine. ... This compound belongs to the isoquinolines and derivatives. ... 1-(3-bromophenyl)-7-chloro-6-methoxy-3,4-dihydroisoquinoline is a solid. …
3-(2,6-difluorophenyl)-2-(methylthio)quinazolin-4(3H)-one
Experimental
Matched Name: … 3-(2,6-difluorophenyl)-2-(methylthio)quinazolin-4(3H)-one …
Matched Iupac: … 3-(2,6-difluorophenyl)-2-(methylsulfanyl)-3,4-dihydroquinazolin-4-one …
Matched Iupac: … 3-(2,6-difluorophenyl)-2-(methylsulfanyl)-3,4-dihydroquinazolin-4-one …
Di-2-pyridylketone 4-cyclohexyl-4-methyl-3-thiosemicarbazone
Di-2-pyridylketone 4-cyclohexyl-4-methyl-3-thiosemicarbazone is under investigation in clinical trial NCT02688101 (Dose-finding and Pharmacokinetic Study of DpC, Administered Orally to Patients With Advanced Solid Tumors).
Investigational
Matched Name: … Di-2-pyridylketone 4-cyclohexyl-4-methyl-3-thiosemicarbazone …
Matched Iupac: … 1-{[bis(pyridin-2-yl)methylidene]amino}-3-cyclohexyl-3-methylthiourea …
Matched Description: … NCT02688101 (Dose-finding and Pharmacokinetic Study of DpC, Administered Orally to Patients With Advanced ... Di-2-pyridylketone 4-cyclohexyl-4-methyl-3-thiosemicarbazone is under investigation in clinical trial …
Matched Iupac: … 1-{[bis(pyridin-2-yl)methylidene]amino}-3-cyclohexyl-3-methylthiourea …
Matched Description: … NCT02688101 (Dose-finding and Pharmacokinetic Study of DpC, Administered Orally to Patients With Advanced ... Di-2-pyridylketone 4-cyclohexyl-4-methyl-3-thiosemicarbazone is under investigation in clinical trial …
(11S)-8-CHLORO-11-[1-(METHYLSULFONYL)PIPERIDIN-4-YL]-6-PIPERAZIN-1-YL-11H-BENZO[5,6]CYCLOHEPTA[1,2-B]PYRIDINE
Experimental
Matched Name: … 11S)-8-CHLORO-11-[1-(METHYLSULFONYL)PIPERIDIN-4-YL]-6-PIPERAZIN-1-YL-11H-BENZO[5,6]CYCLOHEPTA[1,2-B]PYRIDINE …
Matched Iupac: … -1(11),3(8),4,6,9,12,14-heptaene ... (2S)-13-chloro-2-(1-methanesulfonylpiperidin-4-yl)-10-(piperazin-1-yl)-4-azatricyclo[9.4.0.0^{3,8}]pentadeca …
Matched Iupac: … -1(11),3(8),4,6,9,12,14-heptaene ... (2S)-13-chloro-2-(1-methanesulfonylpiperidin-4-yl)-10-(piperazin-1-yl)-4-azatricyclo[9.4.0.0^{3,8}]pentadeca …
N-((1R,2R)-2-(5-CHLORO-1H-INDOLE-2-CARBOXAMIDO)CYCLOHEXYL)-5-METHYL-4,5,6,7-TETRAHYDROTHIAZOLO[5,4-C]PYRIDINE-2-CARBOXAMIDE
Experimental
Matched Name: … -((1R,2R)-2-(5-CHLORO-1H-INDOLE-2-CARBOXAMIDO)CYCLOHEXYL)-5-METHYL-4,5,6,7-TETRAHYDROTHIAZOLO[5,4-C]PYRIDINE …
Matched Iupac: … 5-chloro-N-[(1R,2R)-2-{5-methyl-4H,5H,6H,7H-[1,3]thiazolo[5,4-c]pyridine-2-amido}cyclohexyl]-1H-indole …
Matched Iupac: … 5-chloro-N-[(1R,2R)-2-{5-methyl-4H,5H,6H,7H-[1,3]thiazolo[5,4-c]pyridine-2-amido}cyclohexyl]-1H-indole …
(1R,3R)-5-[(2E)-3-{(1S,3R)-2,2,3-trimethyl-3-[6,6,6-trifluoro-5-hydroxy-5-(trifluoromethyl)hex-3-yn-1-yl]cyclopentyl}prop-2-en-1-ylidene]cyclohexane-1,3-diol
Experimental
Matched Name: … (1R,3R)-5-[(2E)-3-{(1S,3R)-2,2,3-trimethyl-3-[6,6,6-trifluoro-5-hydroxy-5-(trifluoromethyl)hex-3-yn-1 …
Matched Iupac: … (1R,3R)-5-[(2E)-3-[(1S,3R)-2,2,3-trimethyl-3-[6,6,6-trifluoro-5-hydroxy-5-(trifluoromethyl)hex-3-yn-1 …
Matched Iupac: … (1R,3R)-5-[(2E)-3-[(1S,3R)-2,2,3-trimethyl-3-[6,6,6-trifluoro-5-hydroxy-5-(trifluoromethyl)hex-3-yn-1 …
Nintedanib
Nintedanib is a small molecule kinase inhibitor used in the treatment of pulmonary fibrosis, systemic sclerosis-associated interstitial lung disease, and non-small cell lung cancer (NSCLC).[L8453,L8459] It was first approved for use in the United States in 2014. Within the spectrum of idiopathic pulmonary fibrosis treatment options, nintedanib is currently one...
Approved
Matched Synonyms: … methyl (3Z)-3-[(4-{methyl[(4-methylpiperazin-1-yl)acetyl]amino}anilino)(phenyl)methylidene]-2-oxo-2,3 …
Matched Iupac: … methyl (3Z)-3-[({4-[N-methyl-2-(4-methylpiperazin-1-yl)acetamido]phenyl}amino)(phenyl)methylidene]-2- …
Matched Description: … used in the treatment of pulmonary fibrosis, systemic sclerosis-associated interstitial lung disease, and ... fibrosis treatment options, nintedanib is currently one of only two disease-modifying therapies available and ... indicated for the condition (the other being [Pirfenidone]) and as such is used as a first-line treatment …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Iupac: … methyl (3Z)-3-[({4-[N-methyl-2-(4-methylpiperazin-1-yl)acetamido]phenyl}amino)(phenyl)methylidene]-2- …
Matched Description: … used in the treatment of pulmonary fibrosis, systemic sclerosis-associated interstitial lung disease, and ... fibrosis treatment options, nintedanib is currently one of only two disease-modifying therapies available and ... indicated for the condition (the other being [Pirfenidone]) and as such is used as a first-line treatment …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Flutemetamol (18F)
Flutemetamol (18F) is a PET scanning radiopharmaceutical containing the radionuclide fluorine-18. It is indicated for Positron Emission Tomography (PET) imaging of the brain to estimate β amyloid neuritic plaque density in adult patients with cognitive impairment who are being evaluated for Alzheimer's disease (AD) or other causes of cognitive decline.
Approved
Investigational
Matched Synonyms: … 2-[3-(18F)fluoro-4-(methylamino)phenyl]-1,3-benzothiazol-6-ol …
Matched Iupac: … 2-[3-(¹⁸F)fluoro-4-(methylamino)phenyl]-1,3-benzothiazol-6-ol …
Matched Categories: … Indicators and Reagents …
Matched Iupac: … 2-[3-(¹⁸F)fluoro-4-(methylamino)phenyl]-1,3-benzothiazol-6-ol …
Matched Categories: … Indicators and Reagents …
Onvansertib
Onvansertib is under investigation in clinical trial NCT03303339 (Onvansertib in Combination With Either Low-dose Cytarabine or Decitabine in Adult Patients With Acute Myeloid Leukemia (AML).).
Investigational
Matched Synonyms: … 4-methylpiperazin-1-yl)-2-(trifluoromethoxy)phenyl)amino)-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3- …
Matched Iupac: … -{[5-(4-methylpiperazin-1-yl)-2-(trifluoromethoxy)phenyl]amino}-1H,4H,5H-pyrazolo[4,3-h]quinazoline-3- …
Matched Salts cas: … 1263293-37-3 …
Matched Iupac: … -{[5-(4-methylpiperazin-1-yl)-2-(trifluoromethoxy)phenyl]amino}-1H,4H,5H-pyrazolo[4,3-h]quinazoline-3- …
Matched Salts cas: … 1263293-37-3 …
Valine-valine-ganciclovir
Investigational
Matched Synonyms: … L-valine, l-valyl-, 2-((2-amino-1,6-dihydro-6-oxo-9h-purin-9-yl)methoxy)-3-hydroxypropyl ester …
Matched Iupac: … ]-3-methylbutanoate ... (2R)-2-[(2-amino-6-oxo-6,9-dihydro-1H-purin-9-yl)methoxy]-3-hydroxypropyl (2S)-2-[(2S)-2-amino-3-methylbutanamido …
Matched Iupac: … ]-3-methylbutanoate ... (2R)-2-[(2-amino-6-oxo-6,9-dihydro-1H-purin-9-yl)methoxy]-3-hydroxypropyl (2S)-2-[(2S)-2-amino-3-methylbutanamido …
Telaprevir
Telaprevir is a direct acting antiviral medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most common...
Approved
Withdrawn
Matched Synonyms: … (1S,3aR,6aS)-(2S)-2-cyclohexyl-N-(pyrazinylcarbonyl)glycyl-3-methyl-L-valyl-N-((1S)-1-((cyclopropylamino …
Matched Iupac: … (3S)-3-{[(1S,3aR,6aS)-2-[(2S)-2-[(2S)-2-cyclohexyl-2-[(pyrazin-2-yl)formamido]acetamido]-3,3-dimethylbutanoyl …
Matched Description: … Subtitutions at amino acid positions 155, 156, or 168 are known to confer resistance. ... The substitutions of the enzyme's catalytic triad consisting of H58, D82, and S139 are also likely to ... response (SVR), after 12 weeks of daily administration of the combination therapy followed by 12 or 36 …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … INCIVO® TABLETAS RECUBIERTAS 375 MG …
Matched Iupac: … (3S)-3-{[(1S,3aR,6aS)-2-[(2S)-2-[(2S)-2-cyclohexyl-2-[(pyrazin-2-yl)formamido]acetamido]-3,3-dimethylbutanoyl …
Matched Description: … Subtitutions at amino acid positions 155, 156, or 168 are known to confer resistance. ... The substitutions of the enzyme's catalytic triad consisting of H58, D82, and S139 are also likely to ... response (SVR), after 12 weeks of daily administration of the combination therapy followed by 12 or 36 …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … INCIVO® TABLETAS RECUBIERTAS 375 MG …
Mivavotinib
Investigational
Matched Synonyms: … -C]pyridin-3-One ... 6-{[(1r,2s)-2-Aminocyclohexyl]amino}-7-Fluoro-4-(1-Methyl-1h-Pyrazol-4-Yl)-1,2-Dihydro-3h-Pyrrolo[3,4 …
Matched Iupac: … -3-one ... 6-{[(1R,2S)-2-aminocyclohexyl]amino}-7-fluoro-4-(1-methyl-1H-pyrazol-4-yl)-1H,2H,3H-pyrrolo[3,4-c]pyridin …
Matched Salts cas: … 1952251-28-3 …
Matched Salts name: … Mivavotinib citrate ... Mivavotinib hydrochloride …
Matched Iupac: … -3-one ... 6-{[(1R,2S)-2-aminocyclohexyl]amino}-7-fluoro-4-(1-methyl-1H-pyrazol-4-yl)-1H,2H,3H-pyrrolo[3,4-c]pyridin …
Matched Salts cas: … 1952251-28-3 …
Matched Salts name: … Mivavotinib citrate ... Mivavotinib hydrochloride …
Displaying drugs 5101 - 5125 of 5749 in total