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Displaying drugs 501 - 525 of 742 in total
AOC-1020
AOC-1020 is an antibody oligonucleotide conjugate, comprised of a human transferrin receptor 1 targeting, effector function null, humanized IgG1 antibody, a MCC maleimide linker, and a double-stranded siRNA oligonucleotide targeting DUX4.
Investigational
Matched Synonyms: … An antibody oligonucleotide conjugate, comprised of a human transferrin receptor 1 targeting, effector ... function null, humanized IgG1 antibody, a MCC maleimide linker, and a double-stranded siRNA oligonucleotide …
Matched Description: … AOC-1020 is an antibody oligonucleotide conjugate, comprised of a human transferrin receptor 1 targeting ... , effector function null, humanized IgG1 antibody, a MCC maleimide linker, and a double-stranded siRNA …
Matched Description: … AOC-1020 is an antibody oligonucleotide conjugate, comprised of a human transferrin receptor 1 targeting ... , effector function null, humanized IgG1 antibody, a MCC maleimide linker, and a double-stranded siRNA …
NGN-401
NGN-401 is a recombinant serotype 9 adeno-associated virus (AAV) encoding an intron encoding a miRNA generating sequence, complementary miRNA binding sites and a full-length human methyl cytosine binding protein 2 (MECP2). Developed by Neurogene Inc., it is being investigated for the treatment of Rett syndrome.
Investigational
Matched Synonyms: … a full-length human methyl cytosine binding protein 2 (MECP2) ... virus (AAV) encoding an intron encoding a miRNA generating sequence, complementary miRNA binding sites and …
Matched Description: … a full-length human methyl cytosine binding protein 2 (MECP2). ... virus (AAV) encoding an intron encoding a miRNA generating sequence, complementary miRNA binding sites and …
Matched Description: … a full-length human methyl cytosine binding protein 2 (MECP2). ... virus (AAV) encoding an intron encoding a miRNA generating sequence, complementary miRNA binding sites and …
AD-214
Investigational
Matched Synonyms: … 3 of the Fc region of a mutated human IgG1 ... Fc-fusion protein comprised of an anti-CXCR4 i-body tethered at its C-terminus to constant domains 2 and …
Vepsitamab
Investigational
Matched Synonyms: … IMMUNOGLOBULIN, BISPECIFIC, ANTI-(HUMAN MUCIN 17) (HUMAN MONOCLONAL MUC17_CD3_ALT2 SINGLE-CHAIN VARIABLE ... VH1-(GGGGS)3-VL1) FUSION PROTEIN WITH PEPTIDE LINKER (GGGGS) FUSION PROTEIN WITH IMMUNOGLOBULIN ANTI-(HUMAN …
Gresonitamab
Investigational
Matched Synonyms: … IMMUNOGLOBULIN, BISPECIFIC, ANTI-(HUMAN CLAUDIN 18.2) (HUMAN MONOCLONAL HWZV_KLA_L SINGLE-CHAIN VARIABLE ... VH1-(GGGGS)3-VL1) FUSION PROTEIN WITH PEPTIDE LINKER (GGGGS) FUSION PROTEIN WITH IMMUNOGLOBULIN ANTI-(HUMAN …
Libivirumab
Libivirumab is an investigational monoclonal antibody. It is one of the active ingredients in HepeX-B, a drug product containing two human monoclonal antibodies to the hepatitis B virus (HBV) surface antigen.
Investigational
Matched Synonyms: … Immunoglobulin g, anti-(hepatitis b surface antigen) (human monoclonal 17.1.41 heavy chain), disulfide ... with human monoclonal 17.1.41 .kappa. …
Matched Description: … It is one of the active ingredients in HepeX-B, a drug product containing two human monoclonal antibodies ... to the hepatitis B virus (HBV) surface antigen. …
Matched Description: … It is one of the active ingredients in HepeX-B, a drug product containing two human monoclonal antibodies ... to the hepatitis B virus (HBV) surface antigen. …
Mecbotamab vedotin
Mecbotamab vedotin is an anti-Axl humanized monoclonal antibody conjugated to monomethyl auristatin E using a cleavable linker (CAB-Axl-ADC).
Investigational
Matched Synonyms: … BA301 .GAMMA.1-CHAIN), DISULFIDE WITH HUMAN-MUS MUSCULUS MONOCLONAL BA301 .KAPPA. ... -CHAIN, DIMER, THIOETHER WITH N-(((4-((N-(6-(3-MERCAPTO-2,5-DIOXO ... IMMUNOGLOBULIN G1 (DE-450-LYSINE), ANTI-(HUMAN TYROSINE KINASE RECEPTOR AXL) (HUMAN-MUS MUSCULUS MONOCLONAL …
Quisovalimab
Investigational
Matched Synonyms: … TNFSF14) (human-Mus musculus monoclonal SAR252067 γ4-chain), disulfide with human-Mus musculus monoclonal ... Immunoglobulin G4 [230-proline,237-glutamic acid], anti-(human tumor necrosis factor superfamily protein …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Saruplase
Experimental
Matched Synonyms: … KINASE (ENZYME-ACTIVATING), PROURO- (HUMAN CLONE PUK33 REDUCED) ... PROUROKINASE (ENZYME ACTIVATING) (HUMAN CLONE PUK4/PUK18), NONGLYCOSYLATED ... PLASMINOGEN ACTIVATOR, PRO- (HUMAN LIVER UROKINASE-TYPE PROTEIN MOIETY REDUCED) …
Matched Categories: … Enzymes and Coenzymes ... Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins …
Matched Categories: … Enzymes and Coenzymes ... Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins …
Rocatinlimab
Rocatinlimab is a subcutaneously administered anti-OX40 antibody developed for the treatment of moderate-to-severe atopic dermatitis. In clinical trials, it has shown significant efficacy and safety compared to a placebo. The drug works by targeting the OX40 receptor, which plays a role in the immune response associated with atopic dermatitis. Despite...
Investigational
Matched Synonyms: … Anti-CD134 human monoclonal antibody (IgG1, KHK4083 dimer) …
Matched Description: … injection reactions such as fever and chills have been reported. ... In clinical trials, it has shown significant efficacy and safety compared to a placebo. ... Additionally, the diverse genetic backgrounds of patients may influence the drug’s effectiveness and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … injection reactions such as fever and chills have been reported. ... In clinical trials, it has shown significant efficacy and safety compared to a placebo. ... Additionally, the diverse genetic backgrounds of patients may influence the drug’s effectiveness and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Trafermin
Investigational
Matched Synonyms: … Recombinant human basic fibroblast growth factor …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins ... Preparations for Treatment of Wounds and Ulcers …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins ... Preparations for Treatment of Wounds and Ulcers …
Nofazinlimab
Nofazinlimab is under investigation in clinical trial NCT04194775 (A Study of Nofazinlimab (CS1003) in Subjects With Advanced Hepatocellular Carcinoma).
Investigational
Matched Synonyms: … cs1003 .gamma.4-chain), disulfide with human-mus musculus monoclonal cs1003 .kappa. ... Immunoglobulin g4 (223-proline), anti-(human programmed cell death protein 1) (human-mus musculus monoclonal ... Recombinant pd-1 mab cs1003 …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Rulonilimab
Rulonilimab is under investigation in clinical trial NCT05408221 (The Efficacy and Safety of Rulonilimab in Combination With Lenvatinib in Hepatocellular Carcinoma).
Investigational
Matched Synonyms: … 1) (human-mus musculus monoclonal f520 .gamma.1-chain), disulfide with human-mus musculus monoclonal ... Immunoglobulin g1 (251-glutamine,298-alanine,429-leucine), anti-(human programmed cell death protein …
Matched Description: … Rulonilimab is under investigation in clinical trial NCT05408221 (The Efficacy and Safety of Rulonilimab …
Matched Description: … Rulonilimab is under investigation in clinical trial NCT05408221 (The Efficacy and Safety of Rulonilimab …
MDX-1303
MDX-1303 is a fully human antibody against the inhalation anthrax, the most lethal form of illness in humans caused by the Bacillus anthracis bacterium, and targets a protein component of these lethal toxins known as the anthrax protective antigen.
Investigational
Matched Synonyms: … ), DISULFIDE WITH HUMAN MONOCLONAL 5E8 LIGHT CHAIN, DIMER ... IMMUNOGLOBULIN, ANTI-(BACILLUS ANTHRACIS ANTHRAX PROTECTIVE ANTIGEN) (HUMAN MONOCLONAL 5E8 HEAVY CHAIN …
Matched Description: … MDX-1303 is a fully human antibody against the inhalation anthrax, the most lethal form of illness in ... humans caused by the Bacillus anthracis bacterium, and targets a protein component of these lethal toxins …
Matched Description: … MDX-1303 is a fully human antibody against the inhalation anthrax, the most lethal form of illness in ... humans caused by the Bacillus anthracis bacterium, and targets a protein component of these lethal toxins …
Lutikizumab
Lutikizumab is under investigation in clinical trial NCT02087904 (A Study Evaluating the Safety, Efficacy, and Pharmacodynamic Effects of ABT-981 in Patients With Knee Osteoarthritis).
Investigational
Matched Synonyms: … Immunoglobulin, anti-(interleukin 1.beta./interleukin 1.alpha.) ... (synthetic human a-1234138 heavy chain), disulfide with synthetic human a-1234138 light chain, dimer …
Matched Description: … Lutikizumab is under investigation in clinical trial NCT02087904 (A Study Evaluating the Safety, Efficacy, and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … Lutikizumab is under investigation in clinical trial NCT02087904 (A Study Evaluating the Safety, Efficacy, and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Zenocutuzumab
Zenocutuzumab is under investigation in clinical trial NCT03321981 (MCLA-128 With Trastuzumab/chemotherapy in HER2+ and With Endocrine Therapy in ER+ and Low HER2 Breast Cancer).
Investigational
Matched Synonyms: … Immunoglobulin g1, bispecific, anti-(human epidermal growth factor receptors, her2 and her3) (humanized ... clone mcla-128 .gamma.1-chain), disulfide with humanized clone mcla-128 light chain, dimer ... antibody with enhanced antibody-dependent cell-mediated cytotoxicity (adcc) activity targeting her2 and …
Matched Description: … With Endocrine Therapy in ER+ and Low HER2 Breast Cancer). ... under investigation in clinical trial NCT03321981 (MCLA-128 With Trastuzumab/chemotherapy in HER2+ and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … With Endocrine Therapy in ER+ and Low HER2 Breast Cancer). ... under investigation in clinical trial NCT03321981 (MCLA-128 With Trastuzumab/chemotherapy in HER2+ and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Exbivirumab
Exbivirumab is an investigational monoclonal antibody. It is one of the active ingredients in HepeX-B, a drug product containing two human monoclonal antibodies to the hepatitis B virus (HBV) surface antigen.
Investigational
Matched Synonyms: … Immunoglobulin g, anti-(hepatitis b surface antigen) (human monoclonal 19.79.5 heavy chain), disulfide ... with human monoclonal 19.79.5 .lambda. chain, dimer …
Matched Description: … It is one of the active ingredients in HepeX-B, a drug product containing two human monoclonal antibodies ... to the hepatitis B virus (HBV) surface antigen. …
Matched Description: … It is one of the active ingredients in HepeX-B, a drug product containing two human monoclonal antibodies ... to the hepatitis B virus (HBV) surface antigen. …
RBIO-101
RBIO-101 is a recombinant adeno-associated virus vector encoding human CYP4V2 protein.
Investigational
Matched Synonyms: … recombinant adeno-associated virus vector encoding human CYP4V2 protein …
Matched Description: … RBIO-101 is a recombinant adeno-associated virus vector encoding human CYP4V2 protein. …
Matched Description: … RBIO-101 is a recombinant adeno-associated virus vector encoding human CYP4V2 protein. …
Resamirigene bilparvovec
AT132 is under investigation in clinical trial NCT03199469 (Gene Transfer Clinical Study in X-linked Myotubular Myopathy).
Investigational
Matched Synonyms: … DNA (synthetic adeno-associated virus 8 vector AT132 human myotubularin cDNA-specifying) ... Non-replicating adeno-associated viral vector, serotype 8, expressing human myotubularin gene …
VG161
VG161 is an oncolytic virus therapy under investigation for the treatment of cholangiocarcinoma.
Investigational
Matched Synonyms: … Recombinant human IL12/15-PDL1B HSV-1 oncolytic virus Injection …
Lym-1-I-131
Lym-1-I-131 is a monoclonal antibody labeled with iodine-131 (131I) that preferentially targets malignant lymphocytes.
Investigational
Matched Synonyms: … Murine MAb (Lym-1) and Iodine 131-I radiolabeled murine MAb (Lym-1) to human B-cell lymphoma ... Monoclonal antibody LYM-1-I-131 ... Iodine I 131 Lym-1 Monoclonal Antibody …
Matched Name: … Lym-1-I-131 …
Matched Description: … Lym-1-I-131 is a monoclonal antibody labeled with iodine-131 (131I) that preferentially targets malignant …
Matched Name: … Lym-1-I-131 …
Matched Description: … Lym-1-I-131 is a monoclonal antibody labeled with iodine-131 (131I) that preferentially targets malignant …
Opebacan
Investigational
Matched Synonyms: … 1-193-BACTERICIDAL/PERMEABILITY-INCREASING PROTEIN (132-ALANINE) (HUMAN) ... 1-193-BACTERICIDAL/PERMEABILITY-INCREASING PROTEIN (132-ALANINE) (HUMAN REDUCED) …
Canoctakin
Investigational
Matched Synonyms: … -tetra-l-lysine)human interleukin 8 precursor-(34-99)- peptide anti-inflammatory ... Interleukin 8 (synthetic human clone dncxcl8 increased-glycosaminoglycan binding isoform pa401) ... Recombinant dna derived, human interleukin 8 (cxcl8) mutein, produced in escherichia coli: (44,48,97,98 …
Sotigalimab
Sotigalimab is under investigation in clinical trial NCT03123783 (CD40 Agonistic Antibody APX005M in Combination With Nivolumab).
Investigational
Matched Synonyms: … CUNICULUS MONOCLONAL APX005M .GAMMA.1-CHAIN), DISULFIDE WITH HUMAN-ORYCTOLAGUS CUNICULUS MONOCLONAL ... IMMUNOGLOBULIN G1 (270-GLUTAMIC ACID, C-TERMINAL-LYSINE-CLIPPED), ANTI-(HUMAN CD40 ANTIGEN) (HUMAN-ORYCTOLAGUS …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Displaying drugs 501 - 525 of 742 in total