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Displaying drugs 5726 - 5750 of 6380 in total
Investigational
Matched Synonyms: … 2-((2e)-3,7-dimethyl-2,6-octadien-1-yl)-6-(ethylamino)-3-hydroxy-5-pentyl-2,5-cyclohexadiene-1,4-dione ... 2,5-cyclohexadiene-1,4-dione, 2-((2e)-3,7-dimethyl-2,6-octadien-1-yl)-6-(ethylamino)-3-hydroxy-5-pentyl ... 2-(3,7-Dimethyl-Octa-2, 6-Dienyl)-6-Ethylamino-3-Hydroxy-5-Pentyl-[1,4]Benzoquinone …
Matched Iupac: … 2-[(2E)-3,7-dimethylocta-2,6-dien-1-yl]-6-(ethylamino)-3-hydroxy-5-pentylcyclohexa-2,5-diene-1,4-dione …
Investigational
Matched Synonyms: … 2-(4-(4-((1-(107- (4-(fluorophenyl)methoxy)-polyethyleneglycol36))-1H-1,2,3-triazol-4-yl)methoxy)-3,5 ... O,O'-Bis({4-[3,5-diiodo-4-(1-methylene-1,2,3-triazol-4-ylmethoxy)phenoxy]-3,5-diiodophenyl}acetic acid ... O,O′-Bis({4-[3,5-diiodo-4-(1-methylen-1,2,3-triazol-4-ylmethoxy)phenoxy]-3,5-diiodophenyl}acetic acid …
Experimental
Matched Synonyms: … 3',5'-ADP ... 3'-Phosphoadenosine 5'-phosphate ... Adenosine 3',5'-bismonophosphate …
Matched Name: … Adenosine 3',5'-diphosphate …
Matched Iupac: … {[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)oxolan-2-yl]methoxy}phosphonic acid …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
2-Methoxyestradiol (2ME2) is a drug that prevents the formation of new blood vessels that tumors need in order to grow (angiogenesis). It has undergone Phase 1 clinical trials against breast cancers and preclinical studies suggest that 2ME2 could also be effective against inflammatory diseases such as rheumatoid arthritis.
Investigational
Matched Synonyms: … 2-Hydroxyestradiol 2-methyl ether ... 2-Hydroxyestradol 2-methyl ether ... 2-ME2 …
Matched Name: … 2-Methoxyestradiol …
Matched Iupac: … (1S,3aS,3bR,9bS,11aS)-8-methoxy-11a-methyl-1H,2H,3H,3aH,3bH,4H,5H,9bH,10H,11H,11aH-cyclopenta[a]phenanthrene …
Matched Description: … 2-Methoxyestradiol (2ME2) is a drug that prevents the formation of new blood vessels that tumors need ... It has undergone Phase 1 clinical trials against breast cancers and preclinical studies suggest that …
Experimental
Matched Synonyms: … N-amidinoglycine ... N-(aminoiminomethyl)glycine …
Matched Iupac: … 2-[(diaminomethylidene)amino]acetic acid …
Matched Salts cas: … 14901-20-3 ... 81129-50-2
Matched Categories: … Compounds used in a research, industrial, or household setting …
Erythritol is a four-carbon sugar that is found in algae, fungi, and lichens. It is twice as sweet as sucrose and can be used as a coronary vasodilator.
Experimental
Matched Description: … Erythritol is a four-carbon sugar that is found in algae, fungi, and lichens. ... It is twice as sweet as sucrose and can be used as a coronary vasodilator. …
Daglutril is an orally active, mixed neutral endopeptidase/endothelin converting enzyme inhibitor under development for the treatment of essential hypertension and congestive heart failure.
Investigational
Matched Synonyms: … ((3S)-3-{1-((2R)-2-Ethoxycarbonyl-4-phenylbutyl)cyclopentanecarboxamido}-2-oxo-2,3,4,5-tetrahydro-1H- ... 1-benzazepin-1-yl)acetic acid …
Matched Iupac: … 2-[(3S)-3-{1-[(2R)-3-ethoxy-3-oxo-2-(2-phenylethyl)propyl]cyclopentaneamido}-2-oxo-2,3,4,5-tetrahydro ... -1H-1-benzazepin-1-yl]acetic acid …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Vet approved
Matched Synonyms: … 4-amino-N-(6-ethoxy-3-pyridazinyl)benzenesulfonamide ... N1-(6-ethoxy-3-pyridazinyl)sulfanilamide ... N1-(6-ethoxypyridazin-3-yl)sulphanilamide …
Matched Iupac: … 4-amino-N-(6-ethoxypyridazin-3-yl)benzene-1-sulfonamide …
OMS906 is a humanized Igg4 monoclonal antibody against mannan-binding lectin-associated serine protease-3 (MASP-3) currently being developed by Omeros.
Investigational
Matched Synonyms: … (MASP-3) ... immunoglobulin G4 monoclonal antibody directed against mannan-binding lectin-associated serine protease-3
Matched Description: … -3 (MASP-3) currently being developed by Omeros. ... OMS906 is a humanized Igg4 monoclonal antibody against mannan-binding lectin-associated serine protease …
EDI-200 is a fusion protein consisting of human immunoglobim G1 constant region Fc region fused to the human receptor binding domain of ectodysplasin-A1.
Investigational
Matched Description: … EDI-200 is a fusion protein consisting of human immunoglobim G1 constant region Fc region fused to the …
EA-230 is under investigation in clinical trial NCT03145220 (Immunomodulation of EA-230 Following On-pump Coronary Artery Bypass Grafting (CABG)).
Investigational
Matched Synonyms: … (2S)-2-((2-(((2S)-5-AMINO-2-(((2S)-2-AMINOPROPANOYL)AMINO)-5-OXO-PENTANOYL)AMINO)ACETYL)AMINO)-3-METHYL-BUTANOIC …
Sitimagene ceradenovec is a novel gene-based product for the treatment of patients with operable high grade glioma, a type of malignant brain tumour, given in addition to standard surgery and radiotherapy/chemotherapy. It is being developed by Ark Therapeutics.
Investigational
Matched Description: … Sitimagene ceradenovec is a novel gene-based product for the treatment of patients with operable high ... grade glioma, a type of malignant brain tumour, given in addition to standard surgery and radiotherapy …
Experimental
Matched Name: … 2-(cycloheptylmethyl)-1,1-dioxido-1-benzothiophen-6-yl sulfamate …
Matched Iupac: … 2-(cycloheptylmethyl)-1,1-dioxo-1lambda6-benzothiophen-6-yl sulfamate …
Experimental
Matched Name: … 5,5-dimethyl-2-morpholin-4-yl-5,6-dihydro-1,3-benzothiazol-7(4H)-one …
Matched Iupac: … 5,5-dimethyl-2-(morpholin-4-yl)-4,5,6,7-tetrahydro-1,3-benzothiazol-7-one …
Experimental
Matched Name: … 4'-[(1R)-1-amino-2-(2,5-difluorophenyl)ethyl]biphenyl-3-carboxamide …
Matched Iupac: … 4'-[(1R)-1-amino-2-(2,5-difluorophenyl)ethyl]-[1,1'-biphenyl]-3-carboxamide …
Experimental
Matched Name: … N-(7-CARBAMIMIDOYL-NAPHTHALEN-1-YL)-3-HYDROXY-2-METHYL-BENZAMIDE …
Matched Iupac: … N-(7-carbamimidoylnaphthalen-1-yl)-3-hydroxy-2-methylbenzamide …
Experimental
Matched Name: … [2'-HYDROXY-3'-(1H-PYRROLO[3,2-C]PYRIDIN-2-YL)-BIPHENYL-3-YLMETHYL]-UREA …
Matched Iupac: … [(2'-hydroxy-3'-{1H-pyrrolo[3,2-c]pyridin-2-yl}-[1,1'-biphenyl]-3-yl)methyl]urea …
Experimental
Matched Iupac: … ethyl 4-{4-[1-(6-methylpyridazin-3-yl)piperidin-4-yl]butoxy}benzoate …
Experimental
Matched Name: … 4-[5-(2-CARBOXY-1-FORMYL-ETHYLCARBAMOYL)-PYRIDIN-3-YL]-BENZOIC ACID …
Matched Iupac: … 4-(5-{[(2S)-1-carboxy-3-oxopropan-2-yl]carbamoyl}pyridin-3-yl)benzoic acid …
Experimental
Matched Name: … 4-bromo-2-{[(2R)-2-(2-chlorobenzyl)pyrrolidin-1-yl]carbonyl}aniline …
Matched Iupac: … 4-bromo-2-[(2R)-2-[(2-chlorophenyl)methyl]pyrrolidine-1-carbonyl]aniline …
Experimental
Matched Name: … (5R)-5-[(1E)-BUTA-1,3-DIENYL]-4-HYDROXY-3,5-DIMETHYLTHIOPHEN-2(5H)-ONE …
Matched Iupac: … (5R)-5-[(1E)-buta-1,3-dien-1-yl]-4-hydroxy-3,5-dimethyl-2,5-dihydrothiophen-2-one …
Experimental
Matched Name: … 1-tert-butyl-3-(3-methylbenzyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine …
Matched Iupac: … 1-tert-butyl-3-[(3-methylphenyl)methyl]-1H-pyrazolo[3,4-d]pyrimidin-4-amine …
Thrombotic microangiopathies (TMA), including thrombotic thrombocytopenic purpura and atypical hemolytic uremic syndrome, are associated with injury and dysregulation of microvascular endothelium and platelets. Evidence increasingly points to a role for the complement system in TMA.[A241030, A241040] Mannan-associated lectin-binding serine protease-2 (MASP-2) is a major effector in the complement lectin pathway.[A241030,...
Investigational
Matched Synonyms: … (1-445) (HOMO SAPIENS VH (IGHV2-26*01 (94%) (IGHD)-I ... MASP-2 antibody ... ANTI-MASP-2 MONOCLONAL ANTIBODY OMS721 …
Matched Description: … [A241030, A241040] Mannan-associated lectin-binding serine protease-2 (MASP-2) is a major effector in ... [A241030, A241040] Narsoplimab (OMS721), a human IgG4λ anti-MASP-2 antibody, is under consideration as ... [A241030] Evidence increasingly points to a role for the complement system in TMA. …
Experimental
Matched Synonyms: … 2,2'-oxybis(1-methoxyethane) ... di(2-methoxyethyl) ether ... bis(2-methoxyethyl) ether …
Matched Iupac: … 1-methoxy-2-(2-methoxyethoxy)ethane …
Experimental
Matched Synonyms: … (2R)-2-Hydroxy-N-(3-((2-mercaptoethyl)amino)-3-oxopropyl)-3,3-dimethyl-4-(phosphonooxy)butanamide …
Matched Iupac: … [(3R)-3-hydroxy-2,2-dimethyl-3-({2-[(2-sulfanylethyl)carbamoyl]ethyl}carbamoyl)propoxy]phosphonic acid …
Displaying drugs 5726 - 5750 of 6380 in total