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Displaying drugs 5876 - 5900 of 10743 in total
Picoplatin
Picoplatin is a cytotoxic platinum compound in clinical development for the treatment of patients with solid tumors. It causes apoptosis (cell death) by binding to DNA and interfering with DNA replication and transcription.
Investigational
Matched Synonyms: … (SP-4-3)-Amminedichloro(2-methylpyridine)platinium …
(1r)-4-[(1e,3e,5e,7z,9e,11z,13e,15e)-17-Hydroxy-3,7,12,16-Tetramethylheptadeca-1,3,5,7,9,11,13,15-Octaen-1-Yl]-3,5,5-Trimethylcyclohex-3-En-1-Ol
Experimental
Matched Name: … (1r)-4-[(1e,3e,5e,7z,9e,11z,13e,15e)-17-Hydroxy-3,7,12,16-Tetramethylheptadeca-1,3,5,7,9,11,13,15-Octaen …
Matched Iupac: … (1R)-4-[(1E,3E,5E,7Z,9E,11Z,13E,15E)-17-hydroxy-3,7,12,16-tetramethylheptadeca-1,3,5,7,9,11,13,15-octaen …
Matched Iupac: … (1R)-4-[(1E,3E,5E,7Z,9E,11Z,13E,15E)-17-hydroxy-3,7,12,16-tetramethylheptadeca-1,3,5,7,9,11,13,15-octaen …
Ginsenoside C
Nutraceutical
Matched Iupac: … 5-yl]oxy}-6-(hydroxymethyl)oxan-3-yl]oxy}-6-(hydroxymethyl)oxane-3,4,5-triol ... (2S,3R,4S,5S,6R)-2-{[(2R,3R,4S,5S,6R)-4,5-dihydroxy-2-{[(1R,2R,5S,7R,10R,11R,14S,15R,16R)-16-hydroxy- ... -trihydroxyoxan-2-yl]oxy}methyl)oxan-2-yl]oxy}hept-5-en-2-yl]tetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadecan- ... 2,6,6,10,11-pentamethyl-14-[(2S)-6-methyl-2-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-({[(2S,3R,4S,5S)-3,4,5 …
Ulviprubart
Investigational
CD564
Experimental
GW 597599
GW 597599, a neurokinin-1 (NK1) receptor antagonist is currently in phase II trials for chemotherapy-induced vomiting; functional dyspepsia; depression and anxiety.
Investigational
LY-517717
LY517717 is an investigational oral direct inhibitor of activated Factor Xa. It is believed to be Lilly's PMD-3112 (licensed from Amgen).
Investigational
Matched Iupac: … N-[(1R)-2-[4-(1-methylpiperidin-4-yl)piperazin-1-yl]-2-oxo-1-phenylethyl]-1H-indole-6-carboxamide …
CX516
Investigational
GW-590735
Investigational
Matched Iupac: … 2-methyl-2-{4-[({4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl}formamido)methyl]phenoxy}propanoic …
CP-547632
CP-547632 has been used in trials studying the treatment of Ovarian Cancer, Lung Neoplasms, Ovarian Neoplasms, Peritoneal Neoplasms, and Fallopian Tube Cancer, among others.
Investigational
Matched Iupac: … 3-[(4-bromo-2,6-difluorophenyl)methoxy]-5-({[4-(pyrrolidin-1-yl)butyl]carbamoyl}amino)-1,2-thiazole-4 …
LY-518674
LY518674 has been used in trials studying the treatment of Metabolic Syndrome X.
Investigational
Matched Iupac: … 2-methyl-2-[4-(3-{1-[(4-methylphenyl)methyl]-5-oxo-4,5-dihydro-1H-1,2,4-triazol-3-yl}propyl)phenoxy]propanoic …
FT516
FT516 is an investigational and engineered off-the-shelf natural killer (NK) cell therapy originating from induced pluripotent stem cells (iPSC). This compound expresses a high-affinity 158V, CD16 (hnCD16) Fc receptor that has an enhanced binding ability to tumor-targeting antibodies, and is resistant to downregulation. FT516 is currently being tested against acute...
Investigational
VAC-52150
Investigational
IDM-4
IDM-4 is an immuno-designed molecule that completed phase I/II of investigation for the treatment of Leukemia. It is a monoclonal antibody-specific antigen that can selectively target cancer-affected cells by coupling with tumor cell-killing MAK cells, which are derived from the patient's own monocytes. Trials of this drug have most likely...
Investigational
Matched Name: … IDM-4 …
Matched Description: … IDM-4 is an immuno-designed molecule that completed phase I/II of investigation for the treatment of …
Matched Description: … IDM-4 is an immuno-designed molecule that completed phase I/II of investigation for the treatment of …
3-{[(4-methylphenyl)sulfonyl]amino}propyl pyridin-4-ylcarbamate
Experimental
Matched Name: … 3-{[(4-methylphenyl)sulfonyl]amino}propyl pyridin-4-ylcarbamate …
Matched Iupac: … 3-(4-methylbenzenesulfonamido)propyl N-(pyridin-4-yl)carbamate …
Matched Iupac: … 3-(4-methylbenzenesulfonamido)propyl N-(pyridin-4-yl)carbamate …
N-(4-CHLOROPHENYL)-1,2,3,4-TETRAHYDROISOQUINOLINE-7-SULFONAMIDE
Experimental
Matched Name: … N-(4-CHLOROPHENYL)-1,2,3,4-TETRAHYDROISOQUINOLINE-7-SULFONAMIDE …
Matched Iupac: … N-(4-chlorophenyl)-1,2,3,4-tetrahydroisoquinoline-7-sulfonamide …
Matched Iupac: … N-(4-chlorophenyl)-1,2,3,4-tetrahydroisoquinoline-7-sulfonamide …
Macelignan
Macelignan is an NSAID with antioxidant, free radical scavenging, and neuroprotective activities.
Experimental
Matched Synonyms: … (8R,8'S)-7-(3,4-methylenedioxyphenyl)-7'-(4-hydroxy-3-methoxyphenyl)-8,8'-dimethylbutane …
Matched Iupac: … 4-[(2S,3R)-4-(2H-1,3-benzodioxol-5-yl)-2,3-dimethylbutyl]-2-methoxyphenol …
Matched Iupac: … 4-[(2S,3R)-4-(2H-1,3-benzodioxol-5-yl)-2,3-dimethylbutyl]-2-methoxyphenol …
Docarpamine
Investigational
Matched Synonyms: … (-)-(s)-2-acetamido-n-(3,4-dihydroxyphenethyl)-4-(methylthio)butyramide bis(ethyl carbonate) (ester) …
Matched Iupac: … 5-{2-[(2S)-2-acetamido-4-(methylsulfanyl)butanamido]ethyl}-2-[(ethoxycarbonyl)oxy]phenyl ethyl carbonate …
Matched Iupac: … 5-{2-[(2S)-2-acetamido-4-(methylsulfanyl)butanamido]ethyl}-2-[(ethoxycarbonyl)oxy]phenyl ethyl carbonate …
Nelotanserin
Nelotanserin has been used in trials studying the treatment of Lewy Body Dementia, Visual Hallucinations, Dementia With Lewy Bodies, and REM Sleep Behavior Disorder. It is a highly selective antagonist at the 5-HT2A serotonin receptor. It increases non-REM sleep, the most restorative phase of the sleep cycle, without sacrificing REM...
Investigational
Matched Iupac: … 3-[3-(4-bromo-1-methyl-1H-pyrazol-5-yl)-4-methoxyphenyl]-1-(2,4-difluorophenyl)urea …
Matched Description: … It is a highly selective antagonist at the 5-HT2A serotonin receptor. …
Matched Description: … It is a highly selective antagonist at the 5-HT2A serotonin receptor. …
PVX-410 component CS1 239-247(SLFVLGLFL)
Investigational
BQ-788
Investigational
Matched Synonyms: … D-norleucine, n-(((2r,6s)-2,6-dimethyl-1-piperidinyl)carbonyl)-4-methyl-l-leucyl-1-(methoxycarbonyl)- …
INO-4995
INO-4995 is an inositol tetrakisphosphate analog being investigated for Cystic Fibrosis.
Investigational
Maltosyl-Alpha (1,4)-D-Gluconhydroximo-1,5-Lactam
Experimental
Matched Iupac: … (2R,3R,4S,5S,6R)-2-{[(2R,3S,4R,5R,6S)-6-{[(2R,3R,4R,5S)-4,5-dihydroxy-6-(hydroxyamino)-2-(hydroxymethyl …
Displaying drugs 5876 - 5900 of 10743 in total