Displaying drugs 576 - 600 of 779 in total
Covid-19 Coronavirus Artificial Antigen Presenting Cell Vaccine
Through analysis of potential immunogenic targets of the SARS-Cov2 genome, a synthetic ‘minigene’ was developed using domains of viral structural proteins and a polyprotein protease. Specifically, the COVID-19 infection relies on the binding of the Spike protein to an ACEII receptor, and with the described approach, the vaccine uses these...
Investigational
Matched Synonyms: … artificial antigen -Pathogen-specific vaccine …
Matched Name: … Covid-19 Coronavirus Artificial Antigen Presenting Cell Vaccine …
Matched Description: … approach, the vaccine uses these engineered minigenes to express viral proteins, modify artificial antigen …
Matched Name: … Covid-19 Coronavirus Artificial Antigen Presenting Cell Vaccine …
Matched Description: … approach, the vaccine uses these engineered minigenes to express viral proteins, modify artificial antigen …
CLL1-CD33 compound chimeric antigen receptor T cells
Investigational
Matched Synonyms: … Chimeric Antigen Receptor immunotherapy directed against CLL-1 and CD33 …
Matched Name: … CLL1-CD33 compound chimeric antigen receptor T cells …
Matched Name: … CLL1-CD33 compound chimeric antigen receptor T cells …
Epidermal Growth Factor Receptor variant III (EGFRvIII) chimeric antigen receptor T cells
Investigational
Matched Synonyms: … Autologous Chimeric Antigen Receptor (CAR) Modified Recombinant T Cells Targeting EGFRvIII …
Matched Name: … Epidermal Growth Factor Receptor variant III (EGFRvIII) chimeric antigen receptor T cells …
Matched Name: … Epidermal Growth Factor Receptor variant III (EGFRvIII) chimeric antigen receptor T cells …
Polyvalent antigen-KLH conjugate vaccine
Polyvalent antigen-KLH conjugate vaccine is a multivalent cancer vaccine comprised of the five tumor-associated antigens (TAAs) globo H, GM2 ganglioside, Tn-MUC1, TF, and sTn conjugated with the immunoadjuvant keyhole limpet hemocyanin (KLH). It is under investigation in clinical trial NCT01223235 (Polyvalent Vaccine-klh Conjugate + Opt-821 Given in Combination With Bevacizumab).
Investigational
Matched Name: … Polyvalent antigen-KLH conjugate vaccine …
Matched Description: … Polyvalent antigen-KLH conjugate vaccine is a multivalent cancer vaccine comprised of the five tumor-associated …
Matched Description: … Polyvalent antigen-KLH conjugate vaccine is a multivalent cancer vaccine comprised of the five tumor-associated …
Inactivated SARS-Cov-2 Vaccine
Developed by Sinopharm's Wuhan Institute of Biological Products co., this vaccine consists of the WIV04 strain of SARS-CoV-2. This strain was isolated from a patient in Wuhan, cultivated in a Vero cell line, and then subsequently inactivated using B-propiolactone. Double-blind, randomized, placebo-controlled phase 1 (96 participants) and phase 2 (224...
Investigational
Matched Name: … Inactivated SARS-Cov-2 Vaccine …
Matched Description: … ., this vaccine consists of the WIV04 strain of SARS-CoV-2. ... strain was isolated from a patient in Wuhan, cultivated in a Vero cell line, and then subsequently inactivated ... [A220158] Currently, the vaccine is being tested in Phase 3 clinical trial in Abu Dhabi (ChiCTR2000034780 …
Matched Description: … ., this vaccine consists of the WIV04 strain of SARS-CoV-2. ... strain was isolated from a patient in Wuhan, cultivated in a Vero cell line, and then subsequently inactivated ... [A220158] Currently, the vaccine is being tested in Phase 3 clinical trial in Abu Dhabi (ChiCTR2000034780 …
Bacillus calmette-guerin substrain danish 1331 live antigen
BCG SSI has been used in trials studying Tuberculosis.
Investigational
Matched Name: … Bacillus calmette-guerin substrain danish 1331 live antigen …
Bacillus calmette-guerin substrain tokyo 172-1 live antigen
Bacillus calmette-guerin substrain tokyo 172-1 live antigen is under investigation in clinical trial NCT03091660 (S1602: Different Strains of BCG With or Without Vaccine in High Grade Non- Muscle Invasive Bladder Cancer).
Investigational
Matched Name: … Bacillus calmette-guerin substrain tokyo 172-1 live antigen …
Matched Description: … Bacillus calmette-guerin substrain tokyo 172-1 live antigen is under investigation in clinical trial …
Matched Description: … Bacillus calmette-guerin substrain tokyo 172-1 live antigen is under investigation in clinical trial …
Baloramotide
Investigational
Matched Synonyms: … family member 2 (lage-2), cancer/testis antigen 6.1, ct6.1) ... L antigen family member 2, recombinant ... Lage-2, recombinant …
ALLO-715
ALLO-715 is an allogeneic chimeric antigen receptor T Cell therapy targeting B cell maturation antigen (BCMA).
Investigational
Matched Synonyms: … Allogenic Chimeric Antigen Receptor T Cells Targeting B Cell Maturation Antigen (BCMA) …
Matched Description: … ALLO-715 is an allogeneic chimeric antigen receptor T Cell therapy targeting B cell maturation antigen …
Matched Description: … ALLO-715 is an allogeneic chimeric antigen receptor T Cell therapy targeting B cell maturation antigen …
BBIBP-CorV
BBIBP-CorV vaccine contains a SARS-CoV-2 strain inactivated inside Vero Cells. Investigation shows this vaccine induces neutralizing antibodies in several mammalian species while also showing protective efficacy with SARS-CoV-2 challenge in rhesus macaques . As of August 2020, this vaccine is being tested for prophylaxis against COVID-19 in human clinical trials.
Investigational
Matched Synonyms: … Purified inactivated SARS-CoV-2 Vaccine ... Inactivated novel coronavirus (2019-CoV) vaccine (Vero cells) …
Matched Description: … BBIBP-CorV vaccine contains a SARS-CoV-2 strain inactivated inside Vero Cells. ... neutralizing antibodies in several mammalian species while also showing protective efficacy with SARS-CoV-2 …
Matched Description: … BBIBP-CorV vaccine contains a SARS-CoV-2 strain inactivated inside Vero Cells. ... neutralizing antibodies in several mammalian species while also showing protective efficacy with SARS-CoV-2 …
Ocaratuzumab
Ocaratuzumab is a humanized monoclonal antibody directed against CD20. It is being investigated for cancers and autoimmune disorders.
Investigational
Matched Synonyms: … Immunoglobulin G1, anti-(human B-lymphocyte antigen CD20 (B-lymphocyte surface antigen B1, Bp35, leukocyte ... surface antigen Leu-16, membrane-spanning 4-domains subfamily A member 1)) …
Tyrosinase
Tyrosinase is a multi-copper-containing multifunctional metalloenzyme with 4 possible oxidation states.[A231829, A231834, A231839] It is responsible for producing melanin pigment across the phylogenetic spectrum.[A231829, A231834, A231839]
Within mammals, tyrosinase is found specifically in melanocytes in a glycosylated form and plays a critical role in regulating the process of melanin biosynthesis...
Investigational
Matched Synonyms: … Tumor rejection antigen AB …
Rozrolimupab
Rozrolimupab is a recombinant polyclonal antibody consisting of 25 different anti-Rhesus D (RhD) antibodies to replace existing anti-RhD hyperimmune immunoglobulins for the treatment of Idiopathic Thrombocytopenic Purpura (ITP) and the prevention of Hemolytic Disease of Newborns (HDN).
Investigational
Matched Synonyms: … Recombinant human antigen-specific polyclonal antibody (pAb) against RhD antigen expressed in Chinese …
PA3-17
PA3-17 is CD7-directed chimeric antigen receptor (CAR) T-cell therapy.
Investigational
Matched Synonyms: … Chimeric Antigen Receptor T Cells targeting CD7 …
Matched Description: … PA3-17 is CD7-directed chimeric antigen receptor (CAR) T-cell therapy. …
Matched Description: … PA3-17 is CD7-directed chimeric antigen receptor (CAR) T-cell therapy. …
Inactivated SARS-CoV-2 Vaccine (Chinese Academy of Medical Sciences)
The SARS-CoV-2 Inactivated Vaccine is a purified vaccine that contains multiple antigens from the virus and is inactivated in Vero Cells . This vaccine specifically was developed in collaboration with the Chinese Academy of Medical Sciences, West China Second University Hospital, and Yunan Center for Disease Control and Prevention. As...
Investigational
Matched Name: … Inactivated SARS-CoV-2 Vaccine (Chinese Academy of Medical Sciences) …
Matched Description: … The SARS-CoV-2 Inactivated Vaccine is a purified vaccine that contains multiple antigens from the virus ... and is inactivated in Vero Cells[A219758]. …
Matched Description: … The SARS-CoV-2 Inactivated Vaccine is a purified vaccine that contains multiple antigens from the virus ... and is inactivated in Vero Cells[A219758]. …
O-(N-acetyl-alpha-D-galactosaminyl)-L-serine
Experimental
Matched Synonyms: … Tn Antigen …
Matched Iupac: … (2S)-2-amino-3-{[(2S,3R,4R,5R,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}propanoic …
Matched Iupac: … (2S)-2-amino-3-{[(2S,3R,4R,5R,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}propanoic …
GX-19 Vaccine
The GX-19 vaccine is a DNA vaccine created by Genexine, Inc. Company in Gyeonggi, Korea . As of June 2020, the vaccine candidate is undergoing Phase I and Phase IIa trials to determine dose levels for safety and efficacy[A219758,L16488].
Investigational
Matched Synonyms: … DNA vaccine expressing SARS-CoV-2 S-protein antigen …
V-SARS
COVID-19 convalescent plasma is currently being acquired from recovered COVID-19 patients and used as prophylaxis for the virus. This therapeutic concept was applied to the development of V-SARS, which heat inactivates the plasma, and packages it into a once-daily pill form. Immunitor Inc., the sponsor, is currently testing this oral...
Investigational
Matched Synonyms: … Heat inactivated convalescent plasma …
Seviprotimut-L
Seviprotimut-L is under investigation in clinical trial NCT01546571 (Study of a Melanoma Vaccine in Stage Iib, Iic, and III Melanoma Patients).
Investigational
Matched Synonyms: … Human polyvalent shedded antigen vaccine …
BBV152
BBV152 is a vaccine candidate created by the Indian Council of Medical Research (ICMR). The candidate, a whole virion inactivated SARS-CoV-2 vaccine, was developed from a well-known SARS-CoV-2 strain and a vero cell platform (CCL-81) with adjuncts of either aluminum hydroxide gel (Algel) or a novel TLR7/8 agonist adsorbed gel....
Investigational
Matched Synonyms: … Whole-Virion Inactivated SARS-CoV-2 Vaccine …
Matched Description: … The candidate, a whole virion inactivated SARS-CoV-2 vaccine, was developed from a well-known SARS-CoV ... Animal studies in mice, rats, and rabbits reported BBV152 immunogenicity at two separate antigen concentrations ... -2 strain and a vero cell platform (CCL-81) with adjuncts of either aluminum hydroxide gel (Algel) or …
Matched Description: … The candidate, a whole virion inactivated SARS-CoV-2 vaccine, was developed from a well-known SARS-CoV ... Animal studies in mice, rats, and rabbits reported BBV152 immunogenicity at two separate antigen concentrations ... -2 strain and a vero cell platform (CCL-81) with adjuncts of either aluminum hydroxide gel (Algel) or …
YS-ON-001
YS-ON-001 is a combination of an inactivated purified rabies virus (IPRV) and the PIKA adjuvant (Poly I:C, kanamycin and calcium).
Investigational
Matched Synonyms: … Polyinosinic-polycytidylic acid/inactivated rabies virus …
Matched Description: … YS-ON-001 is a combination of an inactivated purified rabies virus (IPRV) and the PIKA adjuvant (Poly …
Matched Description: … YS-ON-001 is a combination of an inactivated purified rabies virus (IPRV) and the PIKA adjuvant (Poly …
CTX130
CTX130 is an allogeneic CRISPR/Cas9-mediated genetically modified CAR T cell therapy targeting CD70 antigen.
Investigational
Matched Synonyms: … Allogeneic CRISPR/Cas9-mediated genetically modified CAR T cells targeting CD70 antigen …
Matched Description: … CTX130 is an allogeneic CRISPR/Cas9-mediated genetically modified CAR T cell therapy targeting CD70 antigen …
Matched Description: … CTX130 is an allogeneic CRISPR/Cas9-mediated genetically modified CAR T cell therapy targeting CD70 antigen …
Anti-CD7 CAR T-cell therapy
Investigational
Matched Synonyms: … A chimeric antigen receptor (CAR) immunotherapy directed against the target protein CD7 …
CTX110
CTX110 is an allogeneic CRISPR/Cas9-mediated genetically modified CAR T cell therapy targeting CD19 antigen.
Investigational
Matched Synonyms: … allogeneic CRISPR/Cas9-mediated genetically modified CAR T cells targeting CD19 antigen …
Matched Description: … CTX110 is an allogeneic CRISPR/Cas9-mediated genetically modified CAR T cell therapy targeting CD19 antigen …
Matched Description: … CTX110 is an allogeneic CRISPR/Cas9-mediated genetically modified CAR T cell therapy targeting CD19 antigen …
Receptor binding domain (RBD) SARS-CoV-2 (COVID-19) hepatitis B surface antigen (HBsAg) virus-like particle (VLP) vaccine
Receptor binding domain SARS-CoV-2 Hepatitis B surface antigen virus-like particle vaccine (RBD SARS-CoV-2 HBsAg VLP vaccine), is a virus-like particle vaccine candidate where the RBD antigen is conjugated to the hepatitis B surface antigen . Virus-like particles (VLPs) are protein-based vaccines that stimulate high immune responses because of the VLPs’...
Investigational
Matched Synonyms: … RBD SARS-CoV-2 HBsAg VLP vaccine …
Matched Name: … Receptor binding domain (RBD) SARS-CoV-2 (COVID-19) hepatitis B surface antigen (HBsAg) virus-like particle …
Matched Description: … Receptor binding domain SARS-CoV-2 Hepatitis B surface antigen virus-like particle vaccine (RBD SARS-CoV ... -2 HBsAg VLP vaccine), is a virus-like particle vaccine candidate where the RBD antigen is conjugated ... to the hepatitis B surface antigen[A226593]. …
Matched Name: … Receptor binding domain (RBD) SARS-CoV-2 (COVID-19) hepatitis B surface antigen (HBsAg) virus-like particle …
Matched Description: … Receptor binding domain SARS-CoV-2 Hepatitis B surface antigen virus-like particle vaccine (RBD SARS-CoV ... -2 HBsAg VLP vaccine), is a virus-like particle vaccine candidate where the RBD antigen is conjugated ... to the hepatitis B surface antigen[A226593]. …
Displaying drugs 576 - 600 of 779 in total