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Displaying drugs 576 - 600 of 2959 in total
Primary biliary cirrhosis, or PBC, is a progressive and chronic condition that leads to hepatic injury often resulting in end-stage liver failure that requires liver transplantation. Obeticholic acid is a farnesoid-X receptor (FXR) agonist used to treat this condition, possibly allowing for increased survival. In 2016, it was granted approval...
Approved
Matched Synonyms: … 6-alpha-ethylchenodeoxycholic acid ... Obeticholic acid ... 6-ethylchenodeoxycholic acid
Matched Name: … Obeticholic acid
Matched Iupac: … 11aR)-5-ethyl-4,7-dihydroxy-9a,11a-dimethyl-hexadecahydro-1H-cyclopenta[a]phenanthren-1-yl]pentanoic acid
Matched Description: … The NDA from Intercept Pharmaceuticals was approved in November 2019 and obeticholic acid is expected ... Primary biliary cirrhosis, or PBC, is a progressive and chronic condition that leads to hepatic injury ... in patients with PBC and advanced cirrhosis (e.g. those with portal hypertension or hepatic decompensation …
Matched Categories: … Bile Acids and Salts ... Bile acids and derivatives ... Alimentary Tract and Metabolism ... Bile and Liver Therapy ... Cholic Acids
A synthetic anti-inflammatory glucocorticoid derived from cortisone. It is biologically inert and converted to prednisolone in the liver. Prednisone was granted FDA approval on 21 February 1955.
Approved
Vet approved
Matched Description: … [A187463] It is biologically inert and converted to [prednisolone] in the liver. …
Matched Categories: … Alimentary Tract and Metabolism ... Prednisolone and Prodrugs ... Sex Hormones and Insulins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … PREDNISON ACIS 5MG ... PREDNISON ACIS 20MG ... PREDNISON ACIS 50MG …
Investigational
Matched Synonyms: … Fumaric acid ... Fumaricum acidum ... (2E)-2-butenedioic acid
Matched Name: … Fumaric acid
Matched Iupac: … (2E)-but-2-enedioic acid
Matched Categories: … Acids, Acyclic ... fumaric acid ... Carboxylic Acids ... Dicarboxylic Acids
Investigational
Matched Synonyms: … Alpha-hydroxyoleic acid ... 2-hydroxyoleic acid ... (z)-2-hydroxyoctadec-9-enoic acid
Matched Name: … Idroxioleic acid
Matched Iupac: … (9Z)-2-hydroxyoctadec-9-enoic acid
Matched Categories: … Fatty Acids ... Fatty Acids, Unsaturated ... Fatty Acids, Monounsaturated …
Experimental
Matched Synonyms: … Loperamide oxide ... Loperamide oxide anhydrous …
Matched Name: … Loperamide oxide
Matched Categories: … Alimentary Tract and Metabolism ... loperamide oxide
Matched Products: … OXI-LOPEMID …
Aripiprazole is an atypical antipsychotic orally indicated for the treatment of schizophrenia, bipolar I, major depressive disorder, irritability associated with autism, and Tourette's. It is also indicated as an injection for agitation associated with schizophrenia or bipolar mania. Aripiprazole exerts its effects through agonism of dopaminergic and 5-HT1A receptors and...
Approved
Investigational
Matched Description: … of alpha-adrenergic and 5-HT2A receptors. ... [L45859] Aripiprazole exerts its effects through agonism of dopaminergic and 5-HT1A receptors and antagonism ... treatment of schizophrenia, bipolar I, major depressive disorder, irritability associated with autism, and
Matched Categories: … Aripiprazole and prodrugs ... Adrenergic alpha-Antagonists ... Adrenergic alpha-1 Receptor Antagonists …
Matched Products: … Abilify Maintena 400 mg powder and solvent for prolonged-release suspension for injection ... ABILIFY MAINTENA POWDER AND SOLVENT FOR PROLONGED RELEASE SUSPENSION FOR INJECTION 400 MG ... ALPEX ARIPRAX 10 MG TABLETAS …
A nucleoside diphosphate sugar which serves as a source of glucuronic acid for polysaccharide biosynthesis. It may also be epimerized to UDP iduronic acid, which donates iduronic acid to polysaccharides. In animals, UDP glucuronic acid is used for formation of many glucosiduronides with various aglycones. [PubChem]
Experimental
Matched Synonyms: … UDP-alpha-D-glucuronate ... UDP-Glucuronic Acid ... uridine diphosphate glucuronic acid
Matched Name: … UDP-alpha-D-glucuronic acid
Matched Iupac: … dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)-3,4,5-trihydroxyoxane-2-carboxylic acid
Matched Description: … It may also be epimerized to UDP iduronic acid, which donates iduronic acid to polysaccharides. ... A nucleoside diphosphate sugar which serves as a source of glucuronic acid for polysaccharide biosynthesis ... In animals, UDP glucuronic acid is used for formation of many glucosiduronides with various aglycones …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Investigational
Matched Synonyms: … Ceric oxide ... Cerium oxide ... Cerium(iv) oxide
D-Alpha-tocopheryl polyethylene glycol 1000 succinate (Tocofersolan, Vedrop), has been developed in Europe as an orally bioavailable source of vitamin E in children suffering from cholestasis . Cholestasis is the reduction or stoppage of bile flow, either to impaired secretion by hepatocytes (liver cells) or obstruction , . Tocofersolan is a...
Approved
Matched Synonyms: … (+)-.ALPHA.-TOCOPHERYL POLYETHYLENE GLYCOL 1000 SUCCINATE ... D-.ALPHA.-TOCOPHEROL POLYETHYLENE GLYCOL 1000 SUCCINATE ... POLY(OXY-1,2-ETHANEDIYL), .ALPHA.-(4-((3,4-DIHYDRO-2,5,7,8-TETRAMETHYL-2-(4,8,12-TRIMETHYLTRIDECYL)-2H …
Matched Description: … Tocofersolan is a polyethylene glycol derivative of α-tocopherol and synthetic water-soluble version ... D-Alpha-tocopheryl polyethylene glycol 1000 succinate (Tocofersolan, Vedrop), has been developed in Europe ... capable of demonstrating antioxidant effects that make it a popular component to include in cosmetics and
Matched Categories: … Alimentary Tract and Metabolism …
Experimental
Matched Synonyms: … Decylamine oxide ... Capric dimethyl amine oxide ... Decyl dimethyl amine oxide
Matched Name: … Capric dimethyl amine oxide
Matched Iupac: … N,N-dimethyldecanamine oxide
Experimental
Matched Synonyms: … Argentous oxide ... Disilver oxide ... Silver(I) oxide
Matched Name: … Silver oxide
Experimental
Investigational
Matched Synonyms: … Atsm copper (ii) ... Copper(ii) diacetyl-di(n4-methyl)thiosemicarbazone ... Diacetyl(n(4)-methylthiosemicarbazonato) copper (ii) …
Matched Name: … Copper(II) dithiosemicarbazone …
Matched Iupac: … copper(2+) [(Z)-N-methyl-N'-[(E)-[(3E)-3-{[(Z)-[(methylamino)(sulfanidyl)methylidene]amino]imino}butan …
Prednisolone acetate is a prednisolone molecule bound to an acetate functional group by an ester bond. Prednisolone acetate was granted FDA approval in 1955.
Approved
Vet approved
Matched Synonyms: … Prednisolone acetate
Matched Name: … Prednisolone acetate
Matched Iupac: … 11a-dimethyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl]-2-oxoethyl acetate
Matched Description: … Prednisolone acetate is a [prednisolone] molecule bound to an acetate functional group by an ester bond ... [L9449] Prednisolone acetate was granted FDA approval in 1955.[L9449] …
Matched Products: … Prednisolone Acetate ... Prednisolone Acetate PF ... PREDNISOLONE ACETATE SUSPENSION 25 mg/ml …
Fludrocortisone is a synthetic mineralocorticoid used in conjunction with hydrocortisone to replace missing endogenous corticosteroids in patients with adrenal insufficiency.[A187169,A187187] It is functionally similar to aldosterone, the body's primary endogenous mineralocorticoid, and is structurally analogous to cortisol, differing only by a fluorine atom at the 9-position of the steroid structure...
Approved
Investigational
Matched International brands: … Florinef Acetaat
Matched Description: … A187187] It is functionally similar to [aldosterone], the body's primary endogenous mineralocorticoid, and
Matched Salts name: … Fludrocortisone acetate
Matched Categories: … Sex Hormones and Insulins ... fludrocortisone and antiinfectives ... fludrocortisone and antiinfectives ... fludrocortisone and antiinfectives ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Florinef Acetate ... Fludrocortisone Acetate ... Florinef Acetate 0.1mg …
Experimental
Matched Synonyms: … Lauramine oxide ... Dimethylaurylamine oxide ... Dimethyldodecylamine oxide
Matched Name: … Dodecyldimethylamine N-oxide
Matched Iupac: … N,N-dimethyldodecanamine oxide
Experimental
Matched Name: … Pantothenyl-Aminoethanol-Acetate Pivalic Acid
A non-essential amino acid that is involved in the metabolic control of cell functions in nerve and brain tissue. It is biosynthesized from aspartic acid and ammonia by asparagine synthetase. (From Concise Encyclopedia Biochemistry and Molecular Biology, 3rd ed)
Approved
Investigational
Nutraceutical
Matched Synonyms: … alpha-aminosuccinamic acid ... Aspartamic acid ... 2-Aminosuccinamic acid
Matched Iupac: … (2S)-2-amino-3-carbamoylpropanoic acid
Matched Description: … It is biosynthesized from aspartic acid and ammonia by asparagine synthetase. ... A non-essential amino acid that is involved in the metabolic control of cell functions in nerve and brain ... (From Concise Encyclopedia Biochemistry and Molecular Biology, 3rd ed) …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Basic ... Amino Acids, Diamino ... Amino Acids, Neutral …
Investigational
Matched Synonyms: … alpha-Methyl-3-phenyl-7-benzofuranacetic acid
Matched Iupac: … 2-(3-phenyl-1-benzofuran-7-yl)propanoic acid
Experimental
Matched Synonyms: … L-alpha-Amino-delta-hydroxyvaleric acid ... 5-Hydroxy-2-aminovaleric acid
Matched Iupac: … (2S)-2-amino-5-hydroxypentanoic acid
Matched Categories: … Amino Acids, Peptides, and Proteins …
Clavulanic acid is a beta-lactamase inhibitor that is frequently combined with Amoxicillin or Ticarcillin to fight antibiotic resistance by preventing their degradation by beta-lactamase enzymes, broadening their spectrum of susceptible bacterial infections. Clavulanic acid is derived from the organism Streptomyces clavuligerus. When it is combined with amoxicillin, clavulanic acid is...
Approved
Vet approved
Matched Synonyms: … Clavulanic acid ... Acide clavulanique ... Acidum clavulanicum …
Matched Name: … Clavulanic acid
Matched Iupac: … (2R,3Z,5R)-3-(2-hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
Matched Description: … [T665] Clavulanic acid is derived from the organism Streptomyces clavuligerus. ... Clavulanic acid is a beta-lactamase inhibitor that is frequently combined with [Amoxicillin] or [Ticarcillin ... [A182228]When it is combined with amoxicillin, clavulanic acid is frequently known as Augmentin, Co-Amoxiclav …
Matched Mixtures name: … ACIX® ... AMOXICILLINA E ACIDO CLAVULANICO KABI ... AMOXICILLINA E ACIDO CLAVULANICO KABI …
Aceclofenac is an oral non-steroidal anti-inflammatory drug (NSAID) with marked anti-inflammatory and analgesic properties used to treat osteoarthritis, rheumatoid arthritis and ankylosing spondylitis. It is reported to have a higher anti-inflammatory action or at least comparable effects than conventional NSAIDs in double-blind studies [A19667, A19668, A19670]. Aceclofenac potently inhibits the...
Approved
Investigational
Matched Synonyms: … glycolic acid [o-(2,6-dichloroanilino)phenyl]acetate ester ... 2-[(2,6-dichlorophenyl)amino]phenylacetoxyacetic acid ... 2-[(2',6'-dichlorophenyl)amino]phenylacetoxyacetic acid
Matched Iupac: … 2-[(2-{2-[(2,6-dichlorophenyl)amino]phenyl}acetyl)oxy]acetic acid
Matched Description: … Aceclofenac is an oral non-steroidal anti-inflammatory drug (NSAID) with marked anti-inflammatory and ... analgesic properties used to treat osteoarthritis, rheumatoid arthritis and ankylosing spondylitis. ... synthesis of prostaglandins, which are inflammatory mediators that cause pain, swelling, inflammation, and
Matched Categories: … Acetic Acid Derivatives and Related Substances ... Acids, Carbocyclic ... Carboxylic Acids ... Antiinflammatory and Antirheumatic Products ... Topical Products for Joint and Muscular Pain …
Approved
Matched Synonyms: … Desoxycortone acetate ... Deoxycorticosterone acetate ... 11-deoxycorticosterone acetate
Matched Name: … Desoxycorticosterone acetate
Matched Iupac: … -oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl]-2-oxoethyl acetate
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Experimental
Matched Synonyms: … Zinc protoporphyrin-9 ... Zinc-protoporphyrin IX …
Matched Name: … Zinc protoporphyrin …
Matched Iupac: … zinc(2+) 4,20-bis(2-carboxyethyl)-9,14-diethenyl-5,10,15,19-tetramethyl-21,22,23,24-tetraazapentacyclo …
Coumarin derivative that acts as a long-acting oral anticoagulant.
Approved
Investigational
Matched Synonyms: … 3-(alpha-Ethylbenzyl)-4-hydroxycoumarin ... 3-(alpha-Phenylpropyl)-4-hydroxycoumarin …
Matched Categories: … Blood and Blood Forming Organs …
Matched Products: … PHENPROCOUMON ACIS 3MG TAB …
Etidronic acid is a first generation bisphosphonate similar to clodronic acid and tiludronic acid. These drugs were developed to mimic the action of pyrophosphate, a regulator of calcification and decalcification. Etidronate’s use has decreased over the years in favor of the third generation, nitrogen containing bisphosphonate zoledronic acid, ibandronic acid,...
Approved
Matched Synonyms: … Etidronic acid ... acide étidronique ... acidum etidronicum …
Matched Name: … Etidronic acid
Matched Iupac: … (1-hydroxy-1-phosphonoethyl)phosphonic acid
Matched Description: … ], [ibandronic acid], [minodronic acid], and [risedronic acid]. ... Etidronic acid is a first generation bisphosphonate similar to [clodronic acid] and [tiludronic acid] ... A203111] These drugs were developed to mimic the action of pyrophosphate, a regulator of calcification and
Matched Categories: … etidronic acid and calcium, sequential ... Drugs Affecting Bone Structure and Mineralization ... etidronic acid
Displaying drugs 576 - 600 of 2959 in total