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Displaying drugs 6026 - 6050 of 10293 in total
2,3-Dihydroxy-Valerianic Acid
Experimental
Matched Iupac: … (2R,3R)-2,3-dihydroxy-3-methylpentanoic acid …
Deoxyepinephrine
Sympathomimetic, vasoconstrictor agent.
Experimental
Matched Synonyms: … 4-(2-methylaminoethyl)pyrocatechol ... 1-(3,4-dihydroxyphenyl)-2-methylaminoethane ... 4-(2-methylamino-ethyl)-benzene-1,2-diol …
Matched Iupac: … 4-[2-(methylamino)ethyl]benzene-1,2-diol …
Matched Iupac: … 4-[2-(methylamino)ethyl]benzene-1,2-diol …
Altiratinib
Investigational
Matched Synonyms: … 1,1-cyclopropanedicarboxamide, n-(4-((2-((cyclopropylcarbonyl)amino)-4-pyridinyl)oxy)-2,5-difluorophenyl ... N-(4-((2-((cyclopropylcarbonyl)amino)pyridin-4-yl)oxy)-2,5-difluorophenyi)-n-(4- fluorophenyl)cyclopropane …
Matched Iupac: … N1-{4-[(2-cyclopropaneamidopyridin-4-yl)oxy]-2,5-difluorophenyl}-N'1-(4-fluorophenyl)cyclopropane-1,1 …
Matched Iupac: … N1-{4-[(2-cyclopropaneamidopyridin-4-yl)oxy]-2,5-difluorophenyl}-N'1-(4-fluorophenyl)cyclopropane-1,1 …
1-(4-fluorophenyl)-N-[3-fluoro-4-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)phenyl]-2-oxo-1,2-dihydropyridine-3-carboxamide
Experimental
Matched Name: … 1-(4-fluorophenyl)-N-[3-fluoro-4-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)phenyl]-2-oxo-1,2-dihydropyridine- ... 3-carboxamide …
Matched Iupac: … N-(3-fluoro-4-{1H-pyrrolo[2,3-b]pyridin-4-yloxy}phenyl)-1-(4-fluorophenyl)-2-oxo-1,2-dihydropyridine- ... 3-carboxamide …
Matched Iupac: … N-(3-fluoro-4-{1H-pyrrolo[2,3-b]pyridin-4-yloxy}phenyl)-1-(4-fluorophenyl)-2-oxo-1,2-dihydropyridine- ... 3-carboxamide …
8-bromo-4-(2-chlorophenyl)-N-(2-hydroxyethyl)-6-methyl-1,3-dioxo-1,2,3,6-tetrahydropyrrolo[3,4-e]indole-7-carboxamide
Experimental
Matched Name: … 8-bromo-4-(2-chlorophenyl)-N-(2-hydroxyethyl)-6-methyl-1,3-dioxo-1,2,3,6-tetrahydropyrrolo[3,4-e]indole …
Matched Iupac: … 8-bromo-4-(2-chlorophenyl)-N-(2-hydroxyethyl)-6-methyl-1,3-dioxo-1H,2H,3H,6H-pyrrolo[3,4-e]indole-7-carboxamide …
Matched Iupac: … 8-bromo-4-(2-chlorophenyl)-N-(2-hydroxyethyl)-6-methyl-1,3-dioxo-1H,2H,3H,6H-pyrrolo[3,4-e]indole-7-carboxamide …
Thenoyltrifluoroacetone
Thenoyltrifluoroacetone is a chelating agent and inhibitor of cellular respiration.
Experimental
Matched Synonyms: … 1,1,1-Trifluoro-3-(2-thenoyl)acetone ... 2-Thenoyltrifluoroacetone ... Perfluoroacetyl(2-thenoyl)methane …
Matched Iupac: … 4,4,4-trifluoro-1-(thiophen-2-yl)butane-1,3-dione …
Matched Iupac: … 4,4,4-trifluoro-1-(thiophen-2-yl)butane-1,3-dione …
Tozuleristide
Tozuleristide is under investigation in clinical trial NCT02464332 (Safety Study of BLZ-100 in Adult Subjects With Sarcoma Undergoing Surgery).
Investigational
Matched Synonyms: … N6.27-(6-(2-(7-(1,1-DIMETHYL-3-(4-SULFONATOBUTYL)-1H-BENZO(E)INDOL-1-IUM-2-YL)HEPTA-2,4,6-TRIENYLIDENE ... )-1,1-DIMETHYL-1,2-DIHYDRO-3H-BENZO(E)INDOL-3-YL)HEXANOYL)(15-ARGININE(K>R),23-ARGININE(K>R))CHLOROTOXIN …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
trans-2-hydroxycinnamic acid
Experimental
Matched Synonyms: … (2E)-3-(2-hydroxyphenyl)-2-propenoic acid ... (2E)-3-(2-hydroxyphenyl)prop-2-enoic acid ... (E)-3-(2-Hydroxyphenyl)-2-propenoic acid …
Matched Name: … trans-2-hydroxycinnamic acid …
Matched Iupac: … (2E)-3-(2-hydroxyphenyl)prop-2-enoic acid …
Matched Name: … trans-2-hydroxycinnamic acid …
Matched Iupac: … (2E)-3-(2-hydroxyphenyl)prop-2-enoic acid …
Aptazapine
Aptazapine (CGS-7525A) was a tetracyclic antidepressant developed in the 1980s. Aptazapine had noradrenergic and specific serotonergic activity. It antagonised α2 adrenergic receptors approximately 10 times more effectively than mianserin, antagonised 5-HT2 receptors, agonised H1 receptors, and did not affect reuptake of serotonin or norepinephrine. Although Aptazapine reached clinical trials, it...
Experimental
Matched Iupac: … 17-methyl-6,14,17-triazatetracyclo[12.4.0.0²,⁶.0⁸,¹³]octadeca-2,4,8(13),9,11-pentaene …
Matched Description: … antagonised α2 adrenergic receptors approximately 10 times more effectively than mianserin, antagonised 5- …
Matched Salts cas: … 71576-41-5 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Description: … antagonised α2 adrenergic receptors approximately 10 times more effectively than mianserin, antagonised 5- …
Matched Salts cas: … 71576-41-5 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Halofuginone
Halofuginone is a low molecular weight quinazolinone alkaloid, and a potent inhibitor of collagen alpha1(I) and matrix metalloproteinase 2 (MMP-2) gene expression. Halofuginone also effectively suppresses tumor progression and metastasis in mice. Collgard Biopharmaceuticals is developing halofuginone for the treatment of scleroderma and received orphan drug designation from the U.S....
Investigational
Vet approved
Matched Synonyms: … (+/-)-trans-7-bromo-6-chloro-3-(3-(3-hydroxy-2-piperidyl)-acetonyl)-4(3H)-quinazolinone …
Matched Iupac: … 7-bromo-6-chloro-3-{3-[(2R,3S)-3-hydroxypiperidin-2-yl]-2-oxopropyl}-3,4-dihydroquinazolin-4-one …
Matched Description: … (MMP-2) gene expression. ... weight quinazolinone alkaloid, and a potent inhibitor of collagen alpha1(I) and matrix metalloproteinase 2 …
Matched Salts cas: … 64924-67-0 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Iupac: … 7-bromo-6-chloro-3-{3-[(2R,3S)-3-hydroxypiperidin-2-yl]-2-oxopropyl}-3,4-dihydroquinazolin-4-one …
Matched Description: … (MMP-2) gene expression. ... weight quinazolinone alkaloid, and a potent inhibitor of collagen alpha1(I) and matrix metalloproteinase 2 …
Matched Salts cas: … 64924-67-0 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Lanimostim
Investigational
Diglyme
Experimental
Matched Synonyms: … di(2-methoxyethyl) ether ... bis(2-methoxyethyl) ether …
Matched Iupac: … 1-methoxy-2-(2-methoxyethoxy)ethane …
Matched Iupac: … 1-methoxy-2-(2-methoxyethoxy)ethane …
Paliroden
Paliroden is an orally active neurotrophic, non-peptidic compound that activates synthesis of endogenous neurotrophines. Studies show that use of paliroden increased the rate of formation of both neural progenitors and mature neurons. It is indicated for use in Alzheimer's Disease and Parkinson’s.
Investigational
Matched Synonyms: … 1-(2-(Biphenyl-4-yl)ethyl)-4-(3-(trifluoromethyl)phenyl)-1,2,3,6-tetrahydropyridine …
Matched Iupac: … 1-(2-{[1,1'-biphenyl]-4-yl}ethyl)-4-[3-(trifluoromethyl)phenyl]-1,2,3,6-tetrahydropyridine …
Matched Iupac: … 1-(2-{[1,1'-biphenyl]-4-yl}ethyl)-4-[3-(trifluoromethyl)phenyl]-1,2,3,6-tetrahydropyridine …
Methionine sulfoximine, (S)-
Investigational
Matched Synonyms: … L-S-(3-Amino-3-carboxypropyl)-S-methylsulfoximine ... (2s)-2-amino-4-((s(s))-s-methylsulfonimidoyl)butanoic acid ... Butanoic acid, 2-amino-4-((s(s))-s-methylsulfonimidoyl)-, (2s)- …
Matched Iupac: … (2S)-2-amino-4-[(S)-imino(methyl)oxo-lambda6-sulfanyl]butanoic acid …
Matched Iupac: … (2S)-2-amino-4-[(S)-imino(methyl)oxo-lambda6-sulfanyl]butanoic acid …
OT-551
OT-551 is a novel small molecule that is topically dosed in an eye drop and has the unique ability to penetrate cell membranes and reach both the front and the back of the eye. It is intended to treat Age-related macular Degeneration (AMD), and preclinical research results indicate additional uses...
Investigational
Phosphoaminophosphonic Acid-Adenylate Ester
5'-Adenylic acid, monoanhydride with imidodiphosphoric acid. An analog of ATP, in which the oxygen atom bridging the beta to the gamma phosphate is replaced by a nitrogen atom. It is a potent competitive inhibitor of soluble and membrane-bound mitochondrial ATPase and also inhibits ATP-dependent reactions of oxidative phosphorylation. [PubChem]
Experimental
Matched Iupac: … ({[({[(2S,3R,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy …
Matched Description: … 5'-Adenylic acid, monoanhydride with imidodiphosphoric acid. …
Matched Description: … 5'-Adenylic acid, monoanhydride with imidodiphosphoric acid. …
(3R)-3-(FLUOROMETHYL)-7-(THIOMORPHOLIN-4-YLSULFONYL)-1,2,3,4-TETRAHYDROISOQUINOLINE
Experimental
Matched Name: … (3R)-3-(FLUOROMETHYL)-7-(THIOMORPHOLIN-4-YLSULFONYL)-1,2,3,4-TETRAHYDROISOQUINOLINE …
Matched Iupac: … (3R)-3-(fluoromethyl)-7-(thiomorpholine-4-sulfonyl)-1,2,3,4-tetrahydroisoquinoline …
Matched Iupac: … (3R)-3-(fluoromethyl)-7-(thiomorpholine-4-sulfonyl)-1,2,3,4-tetrahydroisoquinoline …
Olitigaltin
Olitigaltin has been investigated for the treatment of Idiopathic Pulmonary Fibrosis.
Investigational
Matched Synonyms: … Bis-(3-deoxy-3-(4-(3-fluorophenyl)-1H-1,2,3-triazol-1-yl)-B-D-galactopyranosyl) sulfane …
Matched Iupac: … (2S,3R,4S,5R,6R)-4-[4-(3-fluorophenyl)-1H-1,2,3-triazol-1-yl]-2-{[(2S,3R,4S,5R,6R)-4-[4-(3-fluorophenyl ... )-1H-1,2,3-triazol-1-yl]-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]sulfanyl}-6-(hydroxymethyl)oxane-3,5 …
Matched Iupac: … (2S,3R,4S,5R,6R)-4-[4-(3-fluorophenyl)-1H-1,2,3-triazol-1-yl]-2-{[(2S,3R,4S,5R,6R)-4-[4-(3-fluorophenyl ... )-1H-1,2,3-triazol-1-yl]-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]sulfanyl}-6-(hydroxymethyl)oxane-3,5 …
Isatin
Isatin is an indole derivative first obtained by Erdman and Laurent in 1841 as an oxidation product of Indigo dye with nitric acid and chromic acids. The compound is found in many plants and Schiff bases of Isatin are have been investigated for pharmaceutical applications.
Experimental
Matched Categories: … Heterocyclic Compounds, 2-Ring …
ADXS-31164
Investigational
Pelitinib
Pelitinib (EKB-569) is a potent, low molecular weight, selective, and irreversible inhibitor of epidermal growth factor receptor (EGFR) that is being developed as an anticancer agent.
Investigational
Matched Synonyms: … (2E)-N-(4-((3-chloro-4-fluorophenyl)amino)-3-cyano-7-ethoxy-6-quinolinyl)-4-(dimethylamino)-2-butenamide …
Matched Iupac: … (2E)-N-{4-[(3-chloro-4-fluorophenyl)amino]-3-cyano-7-ethoxyquinolin-6-yl}-4-(dimethylamino)but-2-enamide …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Iupac: … (2E)-N-{4-[(3-chloro-4-fluorophenyl)amino]-3-cyano-7-ethoxyquinolin-6-yl}-4-(dimethylamino)but-2-enamide …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Zardaverine
Experimental
Matched Synonyms: … 6-(4-(Difluoromethoxy)-3-methoxyphenyl)-3(2H)-pyridazinone …
Matched Iupac: … 6-[4-(difluoromethoxy)-3-methoxyphenyl]-2,3-dihydropyridazin-3-one …
Matched Iupac: … 6-[4-(difluoromethoxy)-3-methoxyphenyl]-2,3-dihydropyridazin-3-one …
Etizolam
Etizolam is a thienodiazepine which is chemically related to benzodiazepine (BDZ) drug class; it differs from BDZs in having a benzene ring replaced with a thiophene ring. It is an agonist at GABA-A receptors and possesses amnesic, anxiolytic, anticonvulsant, hypnotic, sedative and skeletal muscle relaxant properties. Initially introduced in 1983...
Experimental
Matched Synonyms: … 4-(o-Chlorophenyl)-2-ethyl-9-methyl-6H-thieno(3,2-f)-s-triazolo(4,3-a)(1,4)diazepine …
Matched Iupac: … 7-(2-chlorophenyl)-4-ethyl-13-methyl-3-thia-1,8,11,12-tetraazatricyclo[8.3.0.0^{2,6}]trideca-2(6),4,7,10,12 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Iupac: … 7-(2-chlorophenyl)-4-ethyl-13-methyl-3-thia-1,8,11,12-tetraazatricyclo[8.3.0.0^{2,6}]trideca-2(6),4,7,10,12 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
METHYL (3R)-3-{[(3R)-3-{[(3R)-3-HYDROXYBUTANOYL]OXY}BUTANOYL]OXY}BUTANOATE
Experimental
Matched Name: … METHYL (3R)-3-{[(3R)-3-{[(3R)-3-HYDROXYBUTANOYL]OXY}BUTANOYL]OXY}BUTANOATE …
Matched Iupac: … (2R)-4-{[(2R)-4-methoxy-4-oxobutan-2-yl]oxy}-4-oxobutan-2-yl (3R)-3-hydroxybutanoate …
Matched Iupac: … (2R)-4-{[(2R)-4-methoxy-4-oxobutan-2-yl]oxy}-4-oxobutan-2-yl (3R)-3-hydroxybutanoate …
Displaying drugs 6026 - 6050 of 10293 in total