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Displaying drugs 6251 - 6275 of 10285 in total

WP-1122

WP-1122 is a prodrug of 2-deoxy-D-glucose (2-DG). It was granted FDA orphan designation for the treatment of glioblastoma multiforme.
Investigational
Matched Synonyms: … 3,6-di-O-acetyl-2-deoxy-D-glucopyranose ... an acetic acid diester of 2-deoxy-D-glucose …
Matched Iupac: … (3R,4R,5R)-6-(acetyloxy)-4,5-dihydroxy-1-oxohexan-3-yl acetate …
Matched Description: … WP-1122 is a prodrug of 2-deoxy-D-glucose (2-DG). …

{[2-(1h-1,2,3-Benzotriazol-1-Yl)-2-(3,4-Difluorophenyl)Propane-1,3-Diyl]Bis[4,1-Phenylene(Difluoromethylene)]}Bis(Phosphonic Acid)

Experimental
Matched Name: … {[2-(1h-1,2,3-Benzotriazol-1-Yl)-2-(3,4-Difluorophenyl)Propane-1,3-Diyl]Bis[4,1-Phenylene(Difluoromethylene …
Matched Iupac: … ({4-[2-(1H-1,2,3-benzotriazol-1-yl)-3-{4-[difluoro(phosphono)methyl]phenyl}-2-(3,4-difluorophenyl)propyl …

Masitinib

Masitinib is a tyrosine-kinase inhibitor used in the treatment of mast cell tumors in dogs. It has been available in Europe since 2009, under the brand name Masivet. In the USA it is distributed under the name Kinavet and has been available for veterinaries since 2011.
Investigational
Vet approved
Matched Synonyms: … 4-((4-METHYLPIPERAZIN-1-YL)METHYL)-N-(4-METHYL-3-((4-PYRIDIN-3-YL-1,3-THIAZOL-2-YL)AMINO)PHENYL)BENZAMIDE …
Matched Iupac: … N-(4-methyl-3-{[4-(pyridin-3-yl)-1,3-thiazol-2-yl]amino}phenyl)-4-[(4-methylpiperazin-1-yl)methyl]benzamide …

(2R)-2-Acetamido-3-(octadecyloxy)propyl 2-(methylsulfanyl)ethyl hydrogen phosphate

Experimental
Matched Synonyms: … 1-Octadecyl-2-acetamido-2-deoxy-SN-glycerol-3-phosphoethylmethyl sulfide …
Matched Name: … (2R)-2-Acetamido-3-(octadecyloxy)propyl 2-(methylsulfanyl)ethyl hydrogen phosphate …
Matched Iupac: … [(2R)-2-acetamido-3-(octadecyloxy)propoxy][2-(methylsulfanyl)ethoxy]phosphinic acid …

1,3,4,9-Tetrahydro-2-(Hydroxybenzoyl)-9-[(4-Hydroxyphenyl)Methyl]-6-Methoxy-2h-Pyrido[3,4-B]Indole

Experimental
Matched Name: … 1,3,4,9-Tetrahydro-2-(Hydroxybenzoyl)-9-[(4-Hydroxyphenyl)Methyl]-6-Methoxy-2h-Pyrido[3,4-B]Indole …
Matched Iupac: … 4-{9-[(4-hydroxyphenyl)methyl]-1H,2H,3H,4H,9H-pyrido[3,4-b]indole-2-carbonyl}phenol …

THIENO[3,2-B]PYRIDINE-2-SULFONIC ACID [1-(1-AMINO-ISOQUINOLIN-7-YLMETHYL)-2-OXO-PYRROLDIN-3-YL]-AMIDE

Experimental
Matched Name: … THIENO[3,2-B]PYRIDINE-2-SULFONIC ACID [1-(1-AMINO-ISOQUINOLIN-7-YLMETHYL)-2-OXO-PYRROLDIN-3-YL]-AMIDE …
Matched Iupac: … N-[(3S)-1-[(1-aminoisoquinolin-7-yl)methyl]-2-oxopyrrolidin-3-yl]thieno[3,2-b]pyridine-2-sulfonamide …

Ethyl biscoumacetate

Ethyl biscoumacetate is a courmarin that is used as an anticoagulant. It has actions similar to those of Warfarin. (From Martindale, The Extra Pharmacopoeia, 30th ed, p226)
Withdrawn
Matched Synonyms: … Ethyl bis(4-hydroxy-2-oxo-2h-1-benzopyran-3-yl)acetate …
Matched Iupac: … ethyl 2,2-bis(4-hydroxy-2-oxo-2H-chromen-3-yl)acetate …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

5,6-dihydroxy-NADP

Experimental
Matched Iupac: … {[(2R,3R,4R,5R)-2-(6-amino-9H-purin-9-yl)-5-[({[({[(2R,3S,4R,5R)-5-[(2S,3S)-5-carbamoyl-2,3-dihydroxy ... }oxy)methyl]-4-hydroxyoxolan-3-yl]oxy}phosphonic acid ... -1,2,3,4-tetrahydropyridin-1-yl]-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl …

DDP733

DDP733 is an oral prokinetic drug which Dynogen is developing as a treatment for both Irritable Bowel Syndrome with constipation (IBS-c) and nocturnal gastroesophageal reflux disease (NGERD). It is a partial agonist of the serotonin type 3 receptor (5-HT3). Serotonin is a neurotransmitter that is known to be involved in...
Investigational
Matched Description: … It is a partial agonist of the serotonin type 3 receptor (5-HT3). …

Alfimeprase

Alfimeprase is a recombinant analog of fibrolase. Fibrolase is a zinc-containing metalloproteinase isolated from the venom of the southern copperhead snake (Agkistrodon contortrix contortrix). It is a small protein that contains 203 residues (Randolph et al. 1992). Alfimeprase is being developed by Nuvelo.
Investigational
Matched Synonyms: … 3-203-FIBROLASE (3-SERINE) (AGKISTRODON CONTORTRIX CONTORTRIX RECOMBINANT) …

8-Benzyl-2-Hydroperoxy-2-(4-Hydroxy-Benzyl)-6-(4-Hydroxy-Phenyl)-2h-Imidazo[1,2-a]Pyrazin-3-One

Experimental
Matched Name: … 8-Benzyl-2-Hydroperoxy-2-(4-Hydroxy-Benzyl)-6-(4-Hydroxy-Phenyl)-2h-Imidazo[1,2-a]Pyrazin-3-One …
Matched Iupac: … -3-one ... (2S)-8-benzyl-2-hydroperoxy-6-(4-hydroxyphenyl)-2-[(4-hydroxyphenyl)methyl]-2H,3H-imidazo[1,2-a]pyrazin …

1-({2-[2-(4-CHLOROPHENYL)ETHYL]-1,3-DIOXOLAN-2-YL}METHYL)-1H-IMIDAZOLE

Experimental
Matched Name: … 1-({2-[2-(4-CHLOROPHENYL)ETHYL]-1,3-DIOXOLAN-2-YL}METHYL)-1H-IMIDAZOLE …
Matched Iupac: … 1-({2-[2-(4-chlorophenyl)ethyl]-1,3-dioxolan-2-yl}methyl)-1H-imidazole …

4-bromo-6-(6-hydroxy-1,2-benzisoxazol-3-yl)benzene-1,3-diol

Experimental
Matched Name: … 4-bromo-6-(6-hydroxy-1,2-benzisoxazol-3-yl)benzene-1,3-diol …
Matched Iupac: … 4-bromo-6-(6-hydroxy-1,2-benzoxazol-3-yl)benzene-1,3-diol …

Cysteinamide

Experimental
Matched Synonyms: … 2-amino-3-mercapto-propionamide …
Matched Iupac: … (2R)-2-amino-3-sulfanylpropanamide …

Silver citrate

Experimental
Matched Synonyms: … 2-hydroxy-1,2,3-propanetricarboxylic acid silver salt …
Matched Iupac: … trisilver(1+) ion 2-hydroxypropane-1,2,3-tricarboxylate …

Volociximab

Investigational

(1S)-1-AMINO-2-(1H-INDOL-3-YL)ETHANOL

Experimental
Matched Name: … (1S)-1-AMINO-2-(1H-INDOL-3-YL)ETHANOL …
Matched Iupac: … (1S)-1-amino-2-(1H-indol-3-yl)ethan-1-ol …

Detomidine

Detomidine is an α2-adrenergic agonist that is used as a horse sedative. Normally, it is administered in the salt form, detomidine hydrochloride. This drug is prescribed by veterinarians and is marketed as Dormosedan. Currently, it is only approved by the FDA for use in horses but has been studied for...
Vet approved
Matched Iupac: … 5-[(2,3-dimethylphenyl)methyl]-1H-imidazole …
Matched Salts cas: … 90038-01-0 …
Matched Categories: … Adrenergic alpha-2 Receptor Agonists …

Melanoma antigen recognized by T-cells 1

Melanoma antigen recognized by T-cells 1 is under investigation in clinical trial NCT01748747 (Vaccine Therapy and Resiquimod in Treating Patients With Stage II-IV Melanoma That Has Been Removed By Surgery).
Investigational

NT-102

Investigational
Matched Synonyms: … 2-[(3-Methylbutyl)amino]-1,4-naphthalenedione …
Matched Iupac: … 2-[(3-methylbutyl)amino]-1,4-dihydronaphthalene-1,4-dione …

(R)-2-Hydroxy-3-Sulfopropanoic Acid

Experimental
Matched Name: … (R)-2-Hydroxy-3-Sulfopropanoic Acid …
Matched Iupac: … (2R)-2-hydroxy-3-sulfopropanoic acid …

6-{4-[4-(4-CHLOROPHENYL)PIPERIDIN-4-YL]PHENYL}-9H-PURINE

Experimental

Ralimetinib

Ralimetinib has been used in trials studying the treatment of Postmenopausal, Advanced Cancer, Adult Glioblastoma, Fallopian Tube Cancer, and Metastatic Breast Cancer, among others.
Investigational
Matched Iupac: … 5-[2-tert-butyl-5-(4-fluorophenyl)-1H-imidazol-4-yl]-3-(2,2-dimethylpropyl)-3H-imidazo[4,5-b]pyridin- ... 2-amine …

(9BETA,13ALPHA,14BETA,17ALPHA)-2-METHOXYESTRA-1,3,5(10)-TRIENE-3,17-DIYL DISULFAMATE

Experimental
Matched Name: … (9BETA,13ALPHA,14BETA,17ALPHA)-2-METHOXYESTRA-1,3,5(10)-TRIENE-3,17-DIYL DISULFAMATE …

Doxofylline

Doxofylline is a methylxanthine derivative with the presence of a dioxolane group in position 7. As a drug used in the treatment of asthma, doxofylline has shown similar efficacy to theophylline but with significantly fewer side effects in animal and human studies. In contrast with other xanthine derivatives, doxofylline does...
Experimental
Matched Iupac: … 7-[(1,3-dioxolan-2-yl)methyl]-1,3-dimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione …
Matched Description: … with other xanthine derivatives, doxofylline does not significantly bind to adenosine alpha-1 or alpha-2 …
Matched Mixtures name: … MUCOFIX 600/200 MG EFERVESAN, 5 ADET ... MUCOFIX 1200/400 MG EFERVESAN TABLET, 5 ADET ... MUCOFIX 900/400 MG EFERVESAN TABLET, 5 ADET …
Matched Categories: … Phosphodiesterase 5 Inhibitors ... Adrenergic beta-2 Receptor Agonists ... Heterocyclic Compounds, 2-Ring …
Matched Products: … PUROXAN® JARABE 2 G/100 ML …
Displaying drugs 6251 - 6275 of 10285 in total