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Displaying drugs 626 - 650 of 774 in total
CR002 is a novel investigational fully human monoclonal antibody that blocks the activity of excess platelet-derived growth factor-D (PDGF-D), a target shown to play a role in kidney inflammation. This is a novel therapeutic approach to treat kidney inflammation.
Investigational
Matched Synonyms: … Human monoclonal antibody against platelet-derived growth factor D …
Matched Description: … CR002 is a novel investigational fully human monoclonal antibody that blocks the activity of excess platelet-derived …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Jojoba oil is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Approved
Experimental
Investigational
Matched Mixtures name: … Mousturizing Gloves and Socks …
Matched Products: … Hydra Luxurious Rose
Midazolam is a short-acting hypnotic-sedative drug with anxiolytic, muscle relaxant, anticonvulsant, sedative, hypnotic, and amnesic properties. It belongs to a class of drugs called benzodiazepines. This drug is unique from others in this class due to its rapid onset of effects and short duration of action. Midazolam is available by...
Approved
Illicit
Matched Description: … and endoscopic procedures as pre-anesthetic medication, and as an adjunct to local anesthesia. ... short-acting hypnotic-sedative drug with anxiolytic, muscle relaxant, anticonvulsant, sedative, hypnotic, and ... This drug is unique from others in this class due to its rapid onset of effects and short duration of …
Matched Categories: … Benzodiazepine hypnotics and sedatives ... Benzodiazepines and benzodiazepine derivatives ... Hypnotics and Sedatives …
Matched Products: … SEDOZ® 5MG/1ML ... SEDOZ ® (1MG/ML) …
Satralizumab is a recombinant humanized monoclonal antibody targeted against human interleukin-6 (IL-6) receptors, similar to tocilizumab, which is produced in Chinese hamster ovary cells and based on an IgG2 framework. Satralizumab is used in the treatment of neuromyelitis optica spectrum disorder (NMOSD), a rare autoimmune inflammatory disorder of the central...
Approved
Matched Synonyms: … Humanised anti-IL-6 receptor monoclonal antibody
Matched Description: … [A218551] It received subsequent approvals in Switzerland and Japan,[A218551] and was approved for use ... 6) receptors, similar to [tocilizumab], which is produced in Chinese hamster ovary cells and based on ... central nervous system (CNS) involving demyelinating lesions in the optic nerve, spinal cord, brainstem, and
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
A166 is an antibody-drug conjugate composed of a novel cytotoxic drug (Duo-5, anti-microtubule agent) site-specifically conjugated to an anti-HER2 antibody (trastuzumab) via a stable protease-cleavable valine citrulline linker.
Investigational
Matched Synonyms: … Recombinant humanized IgG1 anti-HER2 monoclonal antibody conjugated to Duostatin-5 …
Matched Description: … A166 is an antibody-drug conjugate composed of a novel cytotoxic drug (Duo-5, anti-microtubule agent) ... site-specifically conjugated to an anti-HER2 antibody (trastuzumab) via a stable protease-cleavable …
Toralizumab is under investigation in clinical trial NCT03605927 (CD40-L Blockade for Prevention of Acute Graft-versus-host Disease).
Investigational
Matched Synonyms: … Anti-CD 154 human-mouse monoclonal antibody
Matched Categories: … Amino Acids, Peptides, and Proteins …
Ordesekimab is under investigation in clinical trial NCT02633020 (Study to Evaluate the Efficacy and Safety of AMG 714 in Adult Patients With Type II Refractory Celiac Disease).
Investigational
Matched Synonyms: … Human IgG1 anti-IL-15 monoclonal antibody
Matched Description: … Ordesekimab is under investigation in clinical trial NCT02633020 (Study to Evaluate the Efficacy and
Matched Categories: … Amino Acids, Peptides, and Proteins …
An antipsychotic agent used in schizophrenia. [PubChem]
Approved
Matched International brands: … Rosup
Matched Categories: … Diazepines, Oxazepines, Thiazepines and Oxepines …
Salix alba bark volatile oil is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Synonyms: … Golden Willow Bark Water ... Golden Willow Bark Volatile Oil …
AOC 1001 is an antibody oligonucleotide conjugate (AOC), comprised of a human transferrin receptor 1 (TfR1) targeting, effector function null, humanized IgG1 antibody (AV01mAb) conjugated to one small interfering RNA (siRNA).
Investigational
Matched Synonyms: … an antibody oligonucleotide conjugate (AOC), comprised of a human transferrin receptor 1 (TfR1) targeting ... , effector function null, humanized IgG1 antibody (AV01mAb) conjugated to one small interfering RNA ( …
Matched Description: … AOC 1001 is an antibody oligonucleotide conjugate (AOC), comprised of a human transferrin receptor 1 ... (TfR1) targeting, effector function null, humanized IgG1 antibody (AV01mAb) conjugated to one small interfering …
Anetumab ravtansine is under investigation in clinical trial NCT03455556 (Anetumab Ravtansine and Atezolizumab in Treating Participants With Advanced Non-small Cell Lung Cancer).
Investigational
Matched Synonyms: … Anti-mesothelin antibody-drug conjugate BAY 94-9343 …
Matched Description: … Anetumab ravtansine is under investigation in clinical trial NCT03455556 (Anetumab Ravtansine and Atezolizumab …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antibody-drug Conjugates …
CMG901 is an anti-Claudin 18.2 monoclonal antibody conjugated with MMAE payload.
Investigational
Matched Synonyms: … an anti-Claudin 18.2 monoclonal antibody conjugated with MMAE payload …
Matched Description: … CMG901 is an anti-Claudin 18.2 monoclonal antibody conjugated with MMAE payload. …
Investigational
Matched Synonyms: … L19-IL2 Monoclonal antibody-cytokine fusion protein …
Investigational
Matched Synonyms: … Humanized Anti-Globo H Monoclonal Antibody Monomethyl Auristatin E Conjugate …
Cold agglutinin disease (CAD) is a type of autoimmune hemolytic anemia (AIHA) in which autoantibodies directed against red blood cell surface antigens cause hemolysis at low (3-4°C) temperatures.[A245154,L40114] This cold subtype accounts for approximately 15-25% of all AIHA and is more common in the elderly.[A245159,L40114] In approximately 90% of cases,...
Approved
Investigational
Matched Synonyms: … Humanized IgG4 monoclonal antibody against total complement component 1, subcomponent s …
Matched Description: … [A245154,L40114] This cold subtype accounts for approximately 15-25% of all AIHA and is more common in ... IgM) autoantibodies towards the I antigen on erythrocytes - these antibodies react optimally at 4°C and ... is driven by complement activation, which initiates a cascade that ultimately leads to both intra- and
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Experimental
Matched Synonyms: … Golden shower fruit ... Golden shower tree fruit ... Golden shower cassia fruit …
Purslane is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Approved
Experimental
Matched Synonyms: … Portulaca Oleracea Flower/leaf/stem Extract …
Synthetic antimicrobial related to oxolinic acid and nalidixic acid and used in urinary tract infections.
Approved
Investigational
Withdrawn
Matched Synonyms: … 5-Ethyl-8-oxo-5,8-dihydro-1,3-dioxa-5,6-diaza-cyclopenta[b]naphthalene-7-carboxylic acid …
Matched Description: … Synthetic antimicrobial related to oxolinic acid and nalidixic acid and used in urinary tract infections …
Efavirenz (brand names Sustiva® and Stocrin®) is a non-nucleoside reverse transcriptase inhibitor (NNRTI) and is used as part of highly active antiretroviral therapy (HAART) for the treatment of a human immunodeficiency virus (HIV) type 1. For HIV infection that has not previously been treated, efavirenz and lamivudine in combination with...
Approved
Investigational
Matched Synonyms: … (S)-6-chloro-4-cyclopropylethynyl-4-trifluoromethyl-1,4-dihydro-benzo[d][1,3]oxazin-2-one ... 6-chloro-4-(2-cyclopropyl-1-ethynyl)-4-trifluoromethyl-(4S)-1,4-dihydro-2H-benzo[d][1,3]oxazin-2-one …
Matched Description: … Efavirenz (brand names Sustiva® and Stocrin®) is a non-nucleoside reverse transcriptase inhibitor (NNRTI ... For HIV infection that has not previously been treated, efavirenz and lamivudine in combination with ... ) and is used as part of highly active antiretroviral therapy (HAART) for the treatment of a human immunodeficiency …
Matched Mixtures name: … Efavirenz, Lamivudine and Tenofovir Disoproxil Fumarate ... Efavirenz, Lamivudine and Tenofovir Disoproxil Fumarate ... Efavirenz, Lamivudine and Tenofovir Disoproxil Fumarate …
Matched Categories: … Metabolic Side Effects of Drugs and Substances ... lamivudine, tenofovir disoproxil and efavirenz ... emtricitabine, tenofovir disoproxil and efavirenz …
Clove oil is obtained by extraction from the dried flower buds of the clove plant. Traditionally, it has been used as a flavouring spice in foods, or as a fragrance. It is also found in topical analgesics. Clove oil has shown to exert some antimicrobial activities. The antioxidant and antimicrobial...
Approved
Nutraceutical
Matched Synonyms: … Eugenia caryophyllus (clove) flower oil …
Matched Description: … The antioxidant and antimicrobial activity of clove is higher than that of many fruits, vegetables, and ... _gallic acid_ and has great potential for pharmaceutical, cosmetic, food and agricultural applications ... Clove oil is obtained by extraction from the dried flower buds of the clove plant. …
Approved
Experimental
Matched Synonyms: … Curcuma montana root oil …
Carlumab has been used in trials studying the treatment of Cancer and Prostate Cancer.
Investigational
Withdrawn
Matched Synonyms: … Human monoclonal antibody targeting CC-chemokine ligand 2 (CNTO 888) …
Matched Description: … Carlumab has been used in trials studying the treatment of Cancer and Prostate Cancer. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Finafloxacin is a fluoroquinolone antibiotic indicated in the treatment of acute otitis externa (swimmer's ear) caused by the bacteria Pseudomonas aeruginosa and Staphylococcus aureus. Finafloxacin is marketed by Novartis under the brand Xtoro™, and was approved by the FDA in December 2014.
Approved
Investigational
Matched Synonyms: … 8-Cyano-1-cyclopropyl-6-fluoro-7-[(4aS,7aS)-hexahydropyrrolo[3,4-b][1,4]oxazin-6(2H)-yl]-4-oxo-1,4-dihydro …
Matched Description: … the treatment of acute otitis externa (swimmer's ear) caused by the bacteria Pseudomonas aeruginosa and ... Finafloxacin is marketed by Novartis under the brand Xtoro™, and was approved by the FDA in December …
Mirvetuximab soravtansine-gynx (IMGN853) is an antibody-drug conjugate (ADC) formed by a monoclonal antibody (M9346A) that targets folate receptor alpha (FRα), covalently joined by a cleavable disulfide linker to the genotoxic compound DM4 (also known as soravtansine or ravtansine).[A254392,L43967] DM4 is conjugated to the antibody with a drug-to-antibody ratio of 3.5:1....
Approved
Investigational
Matched Synonyms: … Anti-FOLR1-monoclonal-antibody-maytansinoid-conjugate-IMGN-853 …
Matched Description: … with FRα–positive, platinum-resistant epithelial ovarian, fallopian tube, or primary peritoneal cancer who ... DM4 leads to cell-cycle arrest and apoptosis and is also able to diffuse into neighboring cells and induce ... the surface of epithelial tumor cells, characteristic of ovarian, endometrial, triple-negative breast and
Matched Categories: … MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Antibody-drug Conjugates …
Investigational
Matched Synonyms: … A cd33/cd3 bispecific t-cell engager antibody for acute myeloid leukemia therapy …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Displaying drugs 626 - 650 of 774 in total