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Displaying drugs 6701 - 6725 of 13179 in total
Cephalothin group is a solid. This compound belongs to the 1,3-thiazines. These are organic compounds containing 1,3-thiazine, a six-member ring with a nitrogen and a sulfur atom in ring positions 1 and 3 respectively, as well as two double bonds. This substance is known to target beta-lactamase Toho-1 and D-alanyl-D-alanine...
Experimental
Matched Iupac: … -4-carboxylic acid ... (2R)-5-(2-methoxy-2-oxoethyl)-2-[(1R)-2-oxo-1-[2-(thiophen-2-yl)acetamido]ethyl]-3,6-dihydro-2H-1,3-thiazine …
Matched Description: … This substance is known to target beta-lactamase Toho-1 and D-alanyl-D-alanine carboxypeptidase. ... compounds containing 1,3-thiazine, a six-member ring with a nitrogen and a sulfur atom in ring positions 1
CHGN111 is an inhibitor of the mitochondrial enzyme CLK-1 which is a demethoxyubiquinone hydroxylase. Numerous parameters of mitochondrial function are altered when the activity of CLK-1 is reduced, which results in a decrease of ROS at critical cellular sites, as well as in a decrease of systemic oxidative stress. It...
Investigational
Matched Description: … CHGN111 is an inhibitor of the mitochondrial enzyme CLK-1 which is a demethoxyubiquinone hydroxylase. ... Numerous parameters of mitochondrial function are altered when the activity of CLK-1 is reduced, which …
Taspoglutide is a pharmaceutical drug, a glucagon-like peptide-1 agonist (GLP-1 agonist), under investigation for treatment of type 2 diabetes being codeveloped by Ipsen and Roche. In September 2010 Roche halted Phase III clinical trials due to incidences of serious hypersensitivity reactions and gastrointestinal side effects. As of May 2013 no...
Investigational
Matched Iupac: … (4S)-4-[({[(1S,2R)-1-{[(1S)-1-{[(1S,2R)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S ... 1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-5-amino-1-[(1-{[(1S)-4-carbamimidamido-1-carbamoylbutyl]carbamoyl}-1-methylethyl ... {2-[(2S)-2-amino-3-(1H-imidazol-4-yl)propanamido]-2-methylpropanamido}butanoic acid ... -carbamoylpropyl]carbamoyl}methyl)carbamoyl]-3-carboxypropyl]carbamoyl}-3-methylbutyl]carbamoyl}-2-(4- ... carbamoyl}-2-hydroxypropyl]carbamoyl}-2-phenylethyl]carbamoyl}-2-hydroxypropyl]carbamoyl}methyl)carbamoyl]-4- …
Matched Description: … Taspoglutide is a pharmaceutical drug, a glucagon-like peptide-1 agonist (GLP-1 agonist), under investigation …
Matched Categories: … GLP-1 Agonists …
Experimental
Matched Synonyms: … 4-Heptylphenol ... 4-n-Heptylphenol …
Matched Iupac: … 4-heptylphenol …
Experimental
Matched Iupac: … 4-[(1E)-2-(3,5-diamino-1H-pyrazol-4-yl)diazen-1-yl]phenol …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Experimental
Matched Name: … 4-HYDROXYBENZALDEHYDE O-(CYCLOHEXYLCARBONYL)OXIME …
Matched Iupac: … (E)-[(4-hydroxyphenyl)methylidene]amino cyclohexanecarboxylate …
Synephrine, also referred to as, p-synephrine, is naturally occurring alkaloid. It is present in approved drug products as neo-synephrine, its m-substituted analog. p-synephrine and m-synephrine are known for their longer acting adrenergic effects compared to norepinephrine. The similarity of naming between m-synephrine and the unsubstituted form, synephrine, is a source...
Experimental
Matched Iupac: … 4-[1-hydroxy-2-(methylamino)ethyl]phenol …
Octopamine is structurally similar to norepinephrine. It has been used as a nootropic, and therefore it and all of its enantiomer are prohibited by the World Anti-doping Agency (WADA) as of 2014.
Experimental
Matched Iupac: … 4-(2-amino-1-hydroxyethyl)phenol …
Experimental
Matched Iupac: … 3-(2-amino-1-hydroxyethyl)phenol …
Eleclazine has been used in trials studying the treatment of LQT2 Syndrome, Long QT Syndrome, Ischemic Heart Disease, Ventricular Arrhythmia, and Long QT Syndrome Type 3, among others.
Investigational
Matched Synonyms: … 4-(pyrimidin-2-ylmethyl)-7-(4-(trifluoromethoxy)phenyl)-3,4-dihydrobenzo[f][1,4]oxazepin-5(2H)-one …
Matched Iupac: … 4-[(pyrimidin-2-yl)methyl]-7-[4-(trifluoromethoxy)phenyl]-2,3,4,5-tetrahydro-1,4-benzoxazepin-5-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Amlitelimab is under investigation in clinical trial NCT06181435 (A Study to Evaluate the Efficacy and Safety of Subcutaneous Amlitelimab Monotherapy Compared With Placebo in Participants Aged 12 Years and Older With Moderate-to-severe Atopic Dermatitis (COAST 2)).
Investigational
Matched Synonyms: … Immunoglobulin g4 (235-proline,242-glutamic acid), anti-(human ox40 ligand) (human monoclonal ky1005-2d10 .gamma.4- …
Izencitinib is under investigation in clinical trial NCT03920254 (TD-1473 Long-term Safety (LTS) Ulcerative Colitis (UC) Study).
Investigational
Experimental
Matched Name: … (2S)-2-Ammonio-3-[5-(2-methyl-2-propanyl)-3-oxido-1,2-oxazol-4-yl]propanoate …
Matched Iupac: … 4-[(2S)-2-amino-2-carboxyethyl]-5-tert-butyl-1,2-oxazol-3-olate …
Azafenidin is under investigation in clinical trial NCT01726582 (Pancreas Cancer: Molecular Profiling as a Guide to Therapy Before and After Surgery ("Personalized Medicine")).
Investigational
Experimental
Matched Synonyms: … 3,5,3',4'-tetrahydroxystilbene ... 4-[(E)-2-(3,5-dihydroxyphenyl)vinyl]benzene-1,2-diol …
Matched Iupac: … 4-[(1E)-2-(3,5-dihydroxyphenyl)ethenyl]benzene-1,2-diol …
Tocotrienol has been investigated for the treatment of Cholesterol Lowering.
Investigational
Matched Iupac: … 2-methyl-2-[(3E,7E)-4,8,12-trimethyltrideca-3,7,11-trien-1-yl]-3,4-dihydro-2H-1-benzopyran-6-ol …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Experimental
Matched Name: … 9-HYDROXY-4-PHENYL-6H-PYRROLO[3,4-C]CARBAZOLE-1,3-DIONE …
Matched Iupac: … 9-hydroxy-4-phenyl-1H,2H,3H,6H-pyrrolo[3,4-c]carbazole-1,3-dione …
Experimental
Matched Name: … 6-CHLORO-4-(CYCLOHEXYLOXY)-3-PROPYLQUINOLIN-2(1H)-ONE …
Matched Iupac: … 6-chloro-4-(cyclohexyloxy)-3-propyl-1,2-dihydroquinolin-2-one …
Experimental
Matched Name: … 4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)benzoic acid …
Matched Iupac: … 4-{5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl}benzoic acid …
Experimental
Matched Name: … 2-(6-HYDROXY-1,3-BENZOTHIAZOL-2-YL)-1,3-THIAZOL-4(5H)-ONE …
Matched Iupac: … 2-(6-hydroxy-1,3-benzothiazol-2-yl)-4,5-dihydro-1,3-thiazol-4-one …
Suplatast is under investigation in clinical trial NCT05983471 (Efficacy and Safety of ME-015 (Suplatast Tosilate) in Cough Related to Idiopathic Pulmonary Fibrosis (COSMIC-IPF)).
Investigational
Matched Synonyms: … Sulfonium, (3-((4-(3-ethoxy-2-hydroxypropoxy)phenyl)amino)-3-oxopropyl)dimethyl- …
Displaying drugs 6701 - 6725 of 13179 in total