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Displaying drugs 6926 - 6950 of 7941 in total

Patidegib

Patidegib has been investigated for the treatment of Conventional Chondrosarcoma.
Investigational
Matched Iupac: … N-[(3R,3'R,3'aS,4aR,6'S,6aR,6bS,7'aR,9S,12aS,12bS)-3',6',11,12b-tetramethyl-2,3,3'a,4,4',4a,5,5',6,6' ... ,6a,6b,7,7',7'a,8,10,12,12a,12b-icosahydro-1H,3'H-spiro[azuleno[2,1-a]naphthalene-9,2'-furo[3,2-b]pyridine …

Butyrfentanyl

Butyrfentanyl or butyrylfentanyl (not to be confused with 3-methylfentanyl) is a potent short-acting synthetic opioid analgesic drug. It is an analog of fentanyl with roughly 1/30 the potency. Butyrfentanyl was first synthesized in 1961 by Janssen Pharmaceuticals as a new opioid analgesic. Butyrfentanyl has no current legitimate clinical applications, but...
Illicit
Matched Iupac: … N-phenyl-N-[1-(2-phenylethyl)piperidin-4-yl]butanamide …

(3,4-Dihydroxy-Phenyl)-Triphenyl-Arsonium

Experimental

2-(Thiomethylene)-4-Methylpentanoic Acid

Experimental
Matched Name: … 2-(Thiomethylene)-4-Methylpentanoic Acid …
Matched Iupac: … (2S)-4-methyl-2-(sulfanylmethyl)pentanoic acid …

4-Iodobenzo[B]Thiophene-2-Carboxamidine

Experimental
Matched Name: … 4-Iodobenzo[B]Thiophene-2-Carboxamidine …
Matched Iupac: … [amino(4-iodo-1-benzothiophen-2-yl)methylidene]azanium …

4-[(Isopropylamino)Methyl]Phenylalanine

Experimental
Matched Name: … 4-[(Isopropylamino)Methyl]Phenylalanine …
Matched Iupac: … (2S)-2-amino-3-(4-{[(propan-2-yl)amino]methyl}phenyl)propanoic acid …

CIS-4-METHYL-N-[(1S)-3-(METHYLSULFANYL)-1-(PYRIDIN-4-YLCARBAMOYL)PROPYL]CYCLOHEXANECARBOXAMIDE

Experimental
Matched Name: … CIS-4-METHYL-N-[(1S)-3-(METHYLSULFANYL)-1-(PYRIDIN-4-YLCARBAMOYL)PROPYL]CYCLOHEXANECARBOXAMIDE …
Matched Iupac: … (2S)-4-(methylsulfanyl)-N-(pyridin-4-yl)-2-{[(1s,4s)-4-methylcyclohexyl]formamido}butanamide …

Cimetropium

Cimetropium is a semi-synthetic belladonna alkaloid and derivative of scopolamine. It is a potent antimuscarinic and an effective antispasmodic drug. It is also endowed of a direct myolitic action which partially accounts for its antispasmodic activity. It has never been approved for use in the U.S. or Canada.
Experimental
Investigational
Matched Iupac: … (1R,2R,4S,5S,7S)-9-(cyclopropylmethyl)-7-{[(2S)-3-hydroxy-2-phenylpropanoyl]oxy}-9-methyl-3-oxa-9-azatricyclo …

Oxitropium

Oxitropium has been investigated for the treatment of Pulmonary Disease, Chronic Obstructive.
Investigational
Matched Iupac: … (1R,2R,4S,5S,7S)-9-ethyl-7-{[(2S)-3-hydroxy-2-phenylpropanoyl]oxy}-9-methyl-3-oxa-9-azatricyclo[3.3.1.0 …

CC-115

CC-115 has been used in trials studying the treatment of Prostate Cancer, Neoplasm Metastasis, Ewing's Osteosarcoma, Glioblastoma Multiforme, and Chronic Lymphocytic Leukemia, among others.
Investigational
Matched Iupac: … 1-ethyl-7-[2-methyl-6-(4H-1,2,4-triazol-3-yl)pyridin-3-yl]-1H,2H,3H,4H-[1,4]diazino[2,3-b]pyrazin-2-one …

PF-06821497

PF-06821497 is under investigation in clinical trial NCT03460977 (PF-06821497 Treatment Of Relapsed/Refractory SCLC, Castration Resistant Prostate Cancer, and Follicular Lymphoma).
Investigational
Matched Iupac: … 5,8-dichloro-7-[(R)-methoxy(oxetan-3-yl)methyl]-2-[(4-methoxy-6-methyl-2-oxo-1,2-dihydropyridin-3-yl) …

ITI-214

ITI-214 is under investigation in clinical trial NCT03489772 (Study of ITI-214 in Healthy Volunteers to Determine CNS Engagement).
Investigational
Matched Iupac: … (11R,15S)-4-{[4-(6-fluoropyridin-2-yl)phenyl]methyl}-8-methyl-5-(phenylamino)-1,3,4,8,10-pentaazatetracyclo ... [7.6.0.0^{2,6}.0^{11,15}]pentadeca-2,5,9-trien-7-one …

Subasumstat

Subasumstat is under investigation in clinical trial NCT03648372 (A Study to Evaluate the Safety, Tolerability, Preliminary Efficacy and Pharmacokinetics (PK) of TAK-981 in Adult Participants With Advanced or Metastatic Solid Tumors or Relapsed/refractory Hematologic Malignancies and in a Subset With Coronavirus Disease 2019 (COVID-19)).
Investigational
Matched Iupac: … [(1R,2S,4R)-4-[(5-{4-[(1R)-7-chloro-1,2,3,4-tetrahydroisoquinolin-1-yl]-5-methylthiophene-2-carbonyl} ... pyrimidin-4-yl)amino]-2-hydroxycyclopentyl]methyl sulfamate …

INCB-054329

Investigational
Matched Iupac: … (11S)-7-(3,5-dimethyl-1,2-oxazol-4-yl)-11-(pyridin-2-yl)-9-oxa-1,3-diazatricyclo[6.3.1.0^{4,12}]dodeca ... -4(12),5,7-trien-2-one …

Cyclo(his-pro)

Experimental
Matched Synonyms: … (3S,8aS)-3-(1H-Imidazol-4-ylmethyl)hexahydropyrrolo[1,2-a]pyrazine-1,4-dione …
Matched Iupac: … (3S,8aS)-3-[(1H-imidazol-5-yl)methyl]-octahydropyrrolo[1,2-a]pyrazine-1,4-dione …

Apitegromab

Apitegromab is under investigation in clinical trial NCT03921528 (An Active Treatment Study of SRK-015 in Patients With Type 2 or Type 3 Spinal Muscular Atrophy).
Investigational
Matched Synonyms: … g4 (234-proline), anti-(human progrowth differentiation factor 8) (human monoclonal srk-015 .gamma.4- …

Livmoniplimab

Livmoniplimab is under investigation in clinical trial NCT06109272 (A Study to Assess the Dose, Adverse Events, and Change in Disease Activity of Livmoniplimab as an Intravenous (IV) Solution in Combination With Budigalimab as an IV Solution in Adult Participants With Hepatocellular Carcinoma (HCC)).
Investigational
Matched Synonyms: … anti-(human protein garp-transforming growth factor .beta.1 complex) (human monoclonal abbv-151 .gamma.4- …

2-phenyl-1H-imidazole-4-carboxylic acid

Experimental
Matched Name: … 2-phenyl-1H-imidazole-4-carboxylic acid …
Matched Iupac: … 2-phenyl-1H-imidazole-4-carboxylic acid …

(2R)-2-(4-CHLOROPHENYL)-2-PHENYLETHANAMINE

Experimental
Matched Name: … (2R)-2-(4-CHLOROPHENYL)-2-PHENYLETHANAMINE …
Matched Iupac: … (2R)-2-(4-chlorophenyl)-2-phenylethan-1-amine …

3-[4-(AMINOSULFONYL)PHENYL]PROPANOIC ACID

Experimental
Matched Name: … 3-[4-(AMINOSULFONYL)PHENYL]PROPANOIC ACID …
Matched Iupac: … 3-(4-sulfamoylphenyl)propanoic acid …

PVX-410 component CS1 239-247(SLFVLGLFL)

Investigational

4-CHLORO-3',3''-DIBROMOPHENOL-1,8-NAPHTHALEIN

Experimental
Matched Name: … 4-CHLORO-3',3''-DIBROMOPHENOL-1,8-NAPHTHALEIN …
Matched Iupac: … 4,4-bis(3-bromo-4-hydroxyphenyl)-10-chloro-3-oxatricyclo[7.3.1.0^{5,13}]trideca-1(13),5,7,9,11-pentaen …

4-(2-Aminoethyl)Benzenesulfonyl Fluoride

Experimental
Matched Name: … 4-(2-Aminoethyl)Benzenesulfonyl Fluoride …
Matched Iupac: … 4-(2-aminoethyl)benzene-1-sulfonyl fluoride …

Tasosartan

Tasosartan is a long-acting angiotensin II (AngII) receptor blocker. Its long duration of action has been attributed to its active metabolite enoltasosartan. It is used to treat patients with essential hypertension.
Experimental
Matched Iupac: … 2,4-dimethyl-8-{[2'-(2H-1,2,3,4-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl]methyl}-5H,6H,7H,8H-pyrido[2,3-d] ... pyrimidin-7-one …

Relacatib

Investigational
Matched Iupac: … (2S)-2-[(1-benzofuran-2-yl)formamido]-4-methyl-N-[(4S,7R)-7-methyl-3-oxo-1-(pyridine-2-sulfonyl)azepan ... -4-yl]pentanamide …
Displaying drugs 6926 - 6950 of 7941 in total