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Displaying drugs 7276 - 7300 of 12049 in total

VB10.16

VB10.16 is a novel therapeutic antigen-presenting cell-targeting DNA vaccine developed to treat HPV16-positive cancers. It is composed of three parts, one encodes the E6/E7 fusion protein of human papillomavirus (HPV) type 16 (HPV16), a dimerization entity, and the part encoding a protein that specifically binds to antigen-presenting cells (APCs).
Investigational

4-[(CYCLOPROPYLETHYNYL)OXY]-6-FLUORO-3-ISOPROPYLQUINOLIN-2(1H)-ONE

Experimental
Matched Name: … 4-[(CYCLOPROPYLETHYNYL)OXY]-6-FLUORO-3-ISOPROPYLQUINOLIN-2(1H)-ONE …
Matched Iupac: … 4-[(2-cyclopropylethynyl)oxy]-6-fluoro-3-(propan-2-yl)-1,2-dihydroquinolin-2-one …

Icaritin

Icaritin has been used in trials studying the treatment of Solid Tumors, Metastatic Breast Cancer, and Hepatocellular Carcinoma (HCC).
Investigational
Matched Iupac: … 3,5,7-trihydroxy-2-(4-methoxyphenyl)-8-(3-methylbut-2-en-1-yl)-4H-chromen-4-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

5-Bromo-N-[(2S)-2,3-dihydroxypropoxy]-3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]benzamide

Experimental
Matched Name: … 5-Bromo-N-[(2S)-2,3-dihydroxypropoxy]-3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]benzamide …
Matched Iupac: … 5-bromo-N-[(2S)-2,3-dihydroxypropoxy]-3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]benzamide …

tert-butyl [(2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-5-yl)methyl]carbamate

Experimental
Matched Name: … tert-butyl [(2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-5-yl)methyl]carbamate …
Matched Iupac: … tert-butyl N-({2-amino-4-oxo-3H,4H,7H-pyrrolo[2,3-d]pyrimidin-5-yl}methyl)carbamate …

6-PHENYL[5H]PYRROLO[2,3-B]PYRAZINE

Experimental
Matched Iupac: … 4-{7-butyl-5H-pyrrolo[2,3-b]pyrazin-6-yl}phenol …

2-Hexyloxy-6-Hydroxymethyl-Tetrahydro-Pyran-3,4,5-Triol

Experimental

5-Amino-6-cyclohexyl-4-hydroxy-2-isobutyl-hexanoic acid

Experimental
Matched Name: … 5-Amino-6-cyclohexyl-4-hydroxy-2-isobutyl-hexanoic acid …
Matched Iupac: … (2R,4S,5S)-5-amino-6-cyclohexyl-4-hydroxy-2-(2-methylpropyl)hexanoic acid …

BM-3103

Investigational
Matched Synonyms: … 4-Hydroxy-4'-methyoxytolan ... 4-Hydroxy-4′-methoxytolan …

6-{4-[4-(4-CHLOROPHENYL)PIPERIDIN-4-YL]PHENYL}-9H-PURINE

Experimental
Matched Name: … 6-{4-[4-(4-CHLOROPHENYL)PIPERIDIN-4-YL]PHENYL}-9H-PURINE …
Matched Iupac: … 6-{4-[4-(4-chlorophenyl)piperidin-4-yl]phenyl}-9H-purine …

3-hydroxyanthranilic acid

An oxidation product of tryptophan metabolism. It may be a free radical scavenger and a carcinogen.
Experimental

methyl 4-(2,3-dihydroxy-5-methylphenoxy)-2-hydroxy-6-methylbenzoate

Experimental
Matched Name: … methyl 4-(2,3-dihydroxy-5-methylphenoxy)-2-hydroxy-6-methylbenzoate …
Matched Iupac: … methyl 4-(2,3-dihydroxy-5-methylphenoxy)-2-hydroxy-6-methylbenzoate …

Incyclinide

Incyclinide has been used in trials studying the treatment of HIV Infection, AIDS-related Kaposi Sarcoma, Brain and Central Nervous System Tumors, and Unspecified Adult Solid Tumor, Protocol Specific.
Investigational

p-Iodophenol

Experimental
Matched Synonyms: … 4-iodophenol …
Matched Iupac: … 4-iodophenol …

1,3,4,9-Tetrahydro-2-(Hydroxybenzoyl)-9-[(4-Hydroxyphenyl)Methyl]-6-Methoxy-2h-Pyrido[3,4-B]Indole

Experimental
Matched Name: … 1,3,4,9-Tetrahydro-2-(Hydroxybenzoyl)-9-[(4-Hydroxyphenyl)Methyl]-6-Methoxy-2h-Pyrido[3,4-B]Indole …
Matched Iupac: … 4-{9-[(4-hydroxyphenyl)methyl]-1H,2H,3H,4H,9H-pyrido[3,4-b]indole-2-carbonyl}phenol …

6-fluoro-2-(2-hydroxy-3-isobutoxy-phenyl)-1H-benzoimidazole-5-carboxamidine

Experimental
Matched Name: … 6-fluoro-2-(2-hydroxy-3-isobutoxy-phenyl)-1H-benzoimidazole-5-carboxamidine …
Matched Iupac: … 2-{5-[amino(iminiumyl)methyl]-6-fluoro-1H-1,3-benzodiazol-2-yl}-6-(2-methylpropoxy)benzen-1-olate …

4-(Aminosulfonyl)-N-[(2,5-Difluorophenyl)Methyl]-Benzamide

Experimental
Matched Name: … 4-(Aminosulfonyl)-N-[(2,5-Difluorophenyl)Methyl]-Benzamide …
Matched Iupac: … N-[(2,5-difluorophenyl)methyl]-4-sulfamoylbenzamide …

6-CYCLOHEXYLMETHYLOXY-5-NITROSO-PYRIMIDINE-2,4-DIAMINE

Experimental
Matched Name: … 6-CYCLOHEXYLMETHYLOXY-5-NITROSO-PYRIMIDINE-2,4-DIAMINE …
Matched Iupac: … 6-(cyclohexylmethoxy)-5-nitrosopyrimidine-2,4-diamine …

SynOV1.1

SynOV1.1 is an investigational cancer immunotherapy developed by SyngenTech. It is a recombinant oncolytic adenovirus, controlled by synthetic gene circuit, encoding the human immunostimulating factor cytokine granulocyte-macrophage colony-stimulating factor (GM-CSF). SynOV1.1 is under investigation in clinical trial NCT04612504 (Synov1.1 Intratumoral Injection Study).
Investigational

2-(Beta-D-Glucopyranosyl)-5-Methyl-1,2,3-Benzimidazole

Experimental
Matched Name: … 2-(Beta-D-Glucopyranosyl)-5-Methyl-1,2,3-Benzimidazole …

(5R)-5-{[(2-Amino-3H-purin-6-yl)oxy]methyl}-2-pyrrolidinone

Experimental
Matched Name: … (5R)-5-{[(2-Amino-3H-purin-6-yl)oxy]methyl}-2-pyrrolidinone …
Matched Iupac: … (5R)-5-{[(2-amino-9H-purin-6-yl)oxy]methyl}pyrrolidin-2-one …

5'-Deoxy-5'-(Methylthio)-Tubercidin

Experimental
Matched Name: … 5'-Deoxy-5'-(Methylthio)-Tubercidin …
Matched Iupac: … (2R,3R,4S,5S)-2-{4-amino-7H-pyrrolo[2,3-d]pyrimidin-7-yl}-5-[(methylsulfanyl)methyl]oxolane-3,4-diol …

Jaktinib

Jaktinib is a JAK 1, JAK 2 and JAK 3 inhibitor, being developed by Suzhou Zelgen Biopharmaceuticals. Jaktinib is under investigation in clinical trial NCT04866056 (Jaktinib and Azacitidine in Treating Patients With MDS With MF or MDS/MPN With MF.).
Investigational
Matched Description: … Jaktinib is a JAK 1, JAK 2 and JAK 3 inhibitor, being developed by Suzhou Zelgen Biopharmaceuticals. …

2,5-Xylidine

Experimental

AP5346

AP5346 is designed to target a diaminocyclohexane platinum (Pt) moiety to tumors through pH-sensitive linkage to a 25 kDa hydroxypropylmethacrylamide polymer. It is being pursued by Access Pharmaceuticals, Inc.
Investigational
Displaying drugs 7276 - 7300 of 12049 in total