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Displaying drugs 7826 - 7850 of 11340 in total
ECT204
ECT204 is an autologous T-cell therapy whereby T cells are genetically modified to target tumor-specific antigens.
Investigational
3-amino-5-phenylpentane
3-amino-5-phenylpentane is a solid. This compound belongs to the phenylpropylamines. These are compounds containing a phenylpropylamine moiety, which consists of a phenyl group substituted at the third carbon by a propan-1-amine. 3-amino-5-phenylpentane targets the proteins cathepsin K and cathepsin L2.
Experimental
Matched Name: … 3-amino-5-phenylpentane …
Matched Iupac: … (3S)-1-(benzenesulfonyl)-5-phenylpent-1-en-3-amine …
Matched Description: … 3-amino-5-phenylpentane is a solid. This compound belongs to the phenylpropylamines. ... moiety, which consists of a phenyl group substituted at the third carbon by a propan-1-amine. 3-amino-5- …
Matched Iupac: … (3S)-1-(benzenesulfonyl)-5-phenylpent-1-en-3-amine …
Matched Description: … 3-amino-5-phenylpentane is a solid. This compound belongs to the phenylpropylamines. ... moiety, which consists of a phenyl group substituted at the third carbon by a propan-1-amine. 3-amino-5- …
1,3,5-Trimethoxybenzene
Experimental
beta-D-arabinofuranose 5-phosphate
Experimental
Matched Synonyms: … β-D-arabinofuranose 5-phosphate ... 5-O-phosphono-β-D-arabinofuranose …
Matched Name: … beta-D-arabinofuranose 5-phosphate …
Matched Iupac: … {[(2R,3S,4S,5R)-3,4,5-trihydroxyoxolan-2-yl]methoxy}phosphonic acid …
Matched Name: … beta-D-arabinofuranose 5-phosphate …
Matched Iupac: … {[(2R,3S,4S,5R)-3,4,5-trihydroxyoxolan-2-yl]methoxy}phosphonic acid …
1(R)-1-ACETAMIDO-2-(3-CARBOXY-2-HYDROXYPHENYL)ETHYL BORONIC ACID
Experimental
Matched Name: … 1(R)-1-ACETAMIDO-2-(3-CARBOXY-2-HYDROXYPHENYL)ETHYL BORONIC ACID …
Matched Iupac: … 3-[(2R)-2-(dihydroxyboranyl)-2-acetamidoethyl]-2-hydroxybenzoic acid …
Matched Iupac: … 3-[(2R)-2-(dihydroxyboranyl)-2-acetamidoethyl]-2-hydroxybenzoic acid …
Icaritin
Icaritin has been used in trials studying the treatment of Solid Tumors, Metastatic Breast Cancer, and Hepatocellular Carcinoma (HCC).
Investigational
Matched Iupac: … 3,5,7-trihydroxy-2-(4-methoxyphenyl)-8-(3-methylbut-2-en-1-yl)-4H-chromen-4-one …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
NM-3
NM-3 has been used in trials studying the treatment of Neoplasms.
Investigational
Matched Iupac: … 2-(8-hydroxy-6-methoxy-1-oxo-1H-isochromen-3-yl)propanoic acid …
(2r)-2-{[Formyl(Hydroxy)Amino]Methyl}Hexanoic Acid
Experimental
Matched Name: … (2r)-2-{[Formyl(Hydroxy)Amino]Methyl}Hexanoic Acid …
Matched Iupac: … (2R)-2-[(N-hydroxyformamido)methyl]hexanoic acid …
Matched Iupac: … (2R)-2-[(N-hydroxyformamido)methyl]hexanoic acid …
3-[(2,2-DIMETHYLPROPANOYL)AMINO]-N-1,3-THIAZOL-2-YLPYRIDINE-2-CARBOXAMIDE
Experimental
Matched Name: … 3-[(2,2-DIMETHYLPROPANOYL)AMINO]-N-1,3-THIAZOL-2-YLPYRIDINE-2-CARBOXAMIDE …
Matched Iupac: … 3-(2,2-dimethylpropanamido)-N-(1,3-thiazol-2-yl)pyridine-2-carboxamide …
Matched Iupac: … 3-(2,2-dimethylpropanamido)-N-(1,3-thiazol-2-yl)pyridine-2-carboxamide …
Mevalonic acid
Experimental
Eniluracil
Eniluracil, which was previously under development by GlaxoSmithKline (GSK), is being developed by Adherex to enhance the therapeutic value and effectiveness of 5-fluorouracil (5-FU), one of the world’s most widely-used oncology agents. 5-FU is widely used in the U.S. and is often first or second line therapy for a variety...
Investigational
Matched Synonyms: … 5-Ethynyluracil …
Matched Iupac: … 5-ethynyl-1,2,3,4-tetrahydropyrimidine-2,4-dione …
Matched Description: … fluorouracil (5-FU), one of the world’s most widely-used oncology agents. 5-FU is widely used in the ... GlaxoSmithKline (GSK), is being developed by Adherex to enhance the therapeutic value and effectiveness of 5- ... Eniluracil could improve 5-FU by increasing its effectiveness, reducing its side effects and/or making …
Matched Iupac: … 5-ethynyl-1,2,3,4-tetrahydropyrimidine-2,4-dione …
Matched Description: … fluorouracil (5-FU), one of the world’s most widely-used oncology agents. 5-FU is widely used in the ... GlaxoSmithKline (GSK), is being developed by Adherex to enhance the therapeutic value and effectiveness of 5- ... Eniluracil could improve 5-FU by increasing its effectiveness, reducing its side effects and/or making …
Cephalosporin C
Experimental
Matched Synonyms: … 7-(5-Amino-5-carboxyvaleramido)cephalosporanic acid …
Matched Iupac: … -2-ene-2-carboxylic acid ... (6R,7R)-3-[(acetyloxy)methyl]-7-[(5R)-5-amino-5-carboxypentanamido]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Iupac: … -2-ene-2-carboxylic acid ... (6R,7R)-3-[(acetyloxy)methyl]-7-[(5R)-5-amino-5-carboxypentanamido]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Tomaralimab
Tomaralimab is under investigation in clinical trial NCT01794663 (Placebo-Controlled Study to Evaluate the Safety and Efficacy of OPN-305 in Preventing Delayed Renal Graft Function).
Investigational
Matched Synonyms: … Humanized IGG4 monoclonal antibody against toll-like receptor 2 for prevention of ischemia/reperfusion …
Ulapualide A
Experimental
Matched Iupac: … ]-10-methoxy-3,5,9-trimethyl-6-oxoundec-1-en-4-yl acetate ... hydroxy-22-methoxy-10,21-dimethyl-12,18-dioxo-3,7,19,27-tetraoxa-29,30,31-triazatetracyclo[24.2.1.1^{2,5 ... }.1^{6,9}]hentriaconta-1(28),2(31),4,6(30),8,24,26(29)-heptaen-20-yl]-1-[(hydroxymethyl)(methyl)amino …
(2R)-3-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-2-[(9E)-HEXADEC-9-ENOYLOXY]PROPYL (9E)-OCTADEC-9-ENOATE
Experimental
Matched Name: … (2R)-3-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-2-[(9E)-HEXADEC-9-ENOYLOXY]PROPYL (9E …
Matched Iupac: … [(2R)-2,3-dihydroxypropoxy][(2R)-2-[(9Z)-hexadec-9-enoyloxy]-3-[(9Z)-octadec-9-enoyloxy]propoxy]phosphinic …
Matched Iupac: … [(2R)-2,3-dihydroxypropoxy][(2R)-2-[(9Z)-hexadec-9-enoyloxy]-3-[(9Z)-octadec-9-enoyloxy]propoxy]phosphinic …
SAR445136
SAR445136 is an investigational zinc finger nuclease gene-edited cell therapy. It consists of autologous CD34+ hematopoietic stem precursor cells (HSPC) modified ex vivo by zinc finger nucleases (ZFN) that target the BCL11A gene erythroid-specific enhancer (ESE) to increase endogenous HbF production in erythrocytes (RBC). It was formerly investigated for the...
Investigational
N-[2-({[amino(imino)methyl]amino}oxy)ethyl]-2-{6-chloro-3-[(2,2-difluoro-2-phenylethyl)amino]-2-fluorophenyl}acetamide
Experimental
Matched Name: … N-[2-({[amino(imino)methyl]amino}oxy)ethyl]-2-{6-chloro-3-[(2,2-difluoro-2-phenylethyl)amino]-2-fluorophenyl …
Matched Iupac: … 2-{6-chloro-3-[(2,2-difluoro-2-phenylethyl)amino]-2-fluorophenyl}-N-(2-{[(diaminomethylidene)amino]oxy …
Matched Iupac: … 2-{6-chloro-3-[(2,2-difluoro-2-phenylethyl)amino]-2-fluorophenyl}-N-(2-{[(diaminomethylidene)amino]oxy …
Yttrium Y-90 clivatuzumab tetraxetan
Yttrium Y-90 clivatuzumab tetraxetan is under investigation in clinical trial NCT00603863 (Safety and Efficacy Study of Different Doses of 90Y-hPAM4 Combined With Gemcitabine in Pancreatic Cancer).
Investigational
A-674563
Experimental
Matched Synonyms: … (alphaS)-alpha-(((5-(3-Methyl-1H-indazol-5-yl)-3-pyridinyl)oxy)methyl)benzeneethanamine …
Matched Iupac: … (2S)-1-{[5-(3-methyl-1H-indazol-5-yl)pyridin-3-yl]oxy}-3-phenylpropan-2-amine …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Iupac: … (2S)-1-{[5-(3-methyl-1H-indazol-5-yl)pyridin-3-yl]oxy}-3-phenylpropan-2-amine …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
IMIDAZO[2,1-A]ISOQUINOLINE-2-CARBOHYDRAZIDE
Experimental
Matched Name: … IMIDAZO[2,1-A]ISOQUINOLINE-2-CARBOHYDRAZIDE …
Matched Iupac: … imidazo[2,1-a]isoquinoline-2-carbohydrazide …
Matched Iupac: … imidazo[2,1-a]isoquinoline-2-carbohydrazide …
Larcaviximab
Investigational
Blonanserin
Blonanserin is an atypical antipsychotic approved in Japan in January, 2008. It offers improved tolerability as it lacks side effects such as extrapyramidal symptoms, excessive sedation, or hypotension. As a second-generation (atypical) antipsychotic, it is significantly more efficacious in the treatment of the negative symptoms of schizophrenia compared to first-generation...
Investigational
Matched Iupac: … 1-ethyl-4-[4-(4-fluorophenyl)-5H,6H,7H,8H,9H,10H-cycloocta[b]pyridin-2-yl]piperazine …
Matched Categories: … Serotonin 5-HT2 Receptor Antagonists ... Serotonin 5-HT2A Receptor Antagonists …
Matched Categories: … Serotonin 5-HT2 Receptor Antagonists ... Serotonin 5-HT2A Receptor Antagonists …
Ralimetinib
Ralimetinib has been used in trials studying the treatment of Postmenopausal, Advanced Cancer, Adult Glioblastoma, Fallopian Tube Cancer, and Metastatic Breast Cancer, among others.
Investigational
Matched Iupac: … 5-[2-tert-butyl-5-(4-fluorophenyl)-1H-imidazol-4-yl]-3-(2,2-dimethylpropyl)-3H-imidazo[4,5-b]pyridin- ... 2-amine …
Displaying drugs 7826 - 7850 of 11340 in total