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Displaying drugs 7976 - 8000 of 11231 in total
Experimental
Matched Name: … 5-Phosphoarabinonic Acid …
Matched Iupac: … (2S,3R,4R)-2,3,4-trihydroxy-5-(phosphonooxy)pentanoic acid …
Experimental
Matched Name: … Thymidine-3',5'-Diphosphate …
Matched Iupac: … {[(2R,3S,5R)-5-(5-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-3-(phosphonooxy)oxolan-2-yl]methoxy …
Cholesteryl chloride, also known as 3-chlorocholest-5-ene, is an organochloride derivative of cholesterol. It is presented as a liquid crystal that forms clockwise liquid crystals.
Experimental
Matched Synonyms: … 3-Chlorocholest-5-ene …
Matched Iupac: … (1R,3aS,3bS,7S,9aR,9bS,11aR)-7-chloro-9a,11a-dimethyl-1-[(2R)-6-methylheptan-2-yl]-1H,2H,3H,3aH,3bH,4H …
Matched Description: … Cholesteryl chloride, also known as 3-chlorocholest-5-ene, is an organochloride derivative of cholesterol …
VTP-201227 has a novel mechanism of action and is being developed as a topical agent for the treatment of psoriasis with potential extensions into other dermatological indications. It is being developed by Vitae Pharmaceuticals.
Investigational
BMS-275183 has been used in trials studying the treatment of Tumors and Non-small Cell Lung Cancer.
Investigational
Matched Iupac: … -4,4-dimethylpentanoyl]oxy}-1,9-dihydroxy-4-[(methoxycarbonyl)oxy]-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo ... [11.3.1.0^{3,10}.0^{4,7}]heptadec-13-en-2-yl benzoate ... (1S,2S,3R,4S,7R,9S,10S,12R,15S)-12-(acetyloxy)-15-{[(2R,3S)-3-{[(tert-butoxy)carbonyl]amino}-2-hydroxy …
LY2886721 has been used in trials studying the basic science of Alzheimer's Disease.
Investigational
Matched Iupac: … N-{3-[(4aS,7aS)-2-amino-4H,4aH,5H,7H,7aH-furo[3,4-d][1,3]thiazin-7a-yl]-4-fluorophenyl}-5-fluoropyridine ... -2-carboxamide …
LY2874455 has been used in trials studying the treatment of Advanced Cancer.
Investigational
Matched Iupac: … 2-{4-[(E)-2-{5-[(1R)-1-(3,5-dichloropyridin-4-yl)ethoxy]-1H-indazol-3-yl}ethenyl]-1H-pyrazol-1-yl}ethan …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Agn 201904 has been used in trials studying the prevention of Peptic Ulcer.
Investigational
Matched Iupac: … 2-[4-({5-methoxy-2-[(4-methoxy-3,5-dimethylpyridin-2-yl)methanesulfinyl]-1H-1,3-benzodiazol-1-yl}sulfonyl …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... 2-Pyridinylmethylsulfinylbenzimidazoles …
LY-2881835 is under investigation in clinical trial NCT01358981 (A Study of LY2881835 in Healthy People and People With Diabetes).
Investigational
Matched Iupac: … (3S)-3-(4-{[4-({spiro[indene-1,4'-piperidin]-1'-yl}methyl)phenyl]methoxy}phenyl)hex-4-ynoic acid …
GSK-239512 is under investigation in clinical trial NCT00474513 (An Imaging Study to Investigate the Distribution of GSK239512 in the Brain.).
Investigational
Matched Iupac: … 1-{6-[(3-cyclobutyl-2,3,4,5-tetrahydro-1H-3-benzazepin-7-yl)oxy]pyridin-3-yl}pyrrolidin-2-one …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
VXA-CoV2-1 is a non-replicating adenoviral vector-based oral tableted vaccine candidate that expresses a SARS-CoV-2 antigen and dsRNA adjuvant . This oral vaccine aims to induce immunogenicity through induction of potent serum neutralizing antibodies to the SARS-CoV-2 spike protein, induction of mucosal immune responses, and induction of T-cell responses to both...
Investigational
Matched Description: … a non-replicating adenoviral vector-based oral tableted vaccine candidate that expresses a SARS-CoV-2 ... to induce immunogenicity through induction of potent serum neutralizing antibodies to the SARS-CoV-2 ... mucosal immune responses, and induction of T-cell responses to both vaccine antigens of the SARS-CoV-2
Investigational
Matched Synonyms: … Hematopoietic stem cells modified with a lentiviral vector containing the CD18 (integrin beta 2) gene …
Investigational
Experimental
Investigational
Pomotrelvir is under investigation in clinical trial NCT05543707 (PBI-0451 (Pomotrelvir) Phase 2 Study in Nonhospitalized Symptomatic Adults With COVID-19).
Investigational
Matched Synonyms: … 1H-Indole-2-carboxamide, 7-chloro-N-[(1S)-2-[[(1S)-1-cyano-2-[(3S)-2-oxo-3-piperidinyl]ethyl]amino]-1 ... -2-yl]-1H-indole-2-carboxamide ... -(cyclopropylmethyl)-2-oxoethyl]- …
Matched Description: … Pomotrelvir is under investigation in clinical trial NCT05543707 (PBI-0451 (Pomotrelvir) Phase 2 Study …
Experimental
Matched Synonyms: … (2S,3aS,7aS)-2-Carboxyoctahydroindole ... (2S,3aS,7aS)-Octahydroindole-2-carboxylic acid …
Matched Name: … L-Octahydroindole-2-carboxylic acid …
Matched Iupac: … (2S,3aS,7aS)-octahydro-1H-indole-2-carboxylic acid …
Ubamatamab is under investigation in clinical trial NCT03564340 (Study of REGN4018 Administered Alone or in Combination With Cemiplimab in Adult Patients With Recurrent Ovarian Cancer or Other Recurrent Mucin-16 Expressing (MUC16+) Cancers).
Investigational
Experimental
Matched Name: … N-[2-({[amino(imino)methyl]amino}oxy)ethyl]-2-{6-chloro-3-[(2,2-difluoro-2-phenylethyl)amino]-2-fluorophenyl …
Matched Iupac: … 2-{6-chloro-3-[(2,2-difluoro-2-phenylethyl)amino]-2-fluorophenyl}-N-(2-{[(diaminomethylidene)amino]oxy …
Experimental
Matched Synonyms: … (R)-(+)-Tetrahydro-2-furoic acid ... (S)-(-)-2-Tetrahydrofuroic acid ... (2R)-Tetrahydro-2-furancarboxylic acid …
Matched Name: … (S)-2-Tetrahydrofuroic acid …
Matched Iupac: … (2R)-oxolane-2-carboxylic acid …
Guanosine 5'-monophosphate. A guanine nucleotide containing one phosphate group esterified to the sugar moiety and found widely in nature. [PubChem]
Experimental
Matched Name: … Guanosine-5'-Monophosphate …
Matched Iupac: … {[(2R,3S,4R,5R)-5-(2-amino-6-oxo-6,9-dihydro-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}phosphonic …
Matched Description: … Guanosine 5'-monophosphate. …
Experimental
A thiol-containing non-essential amino acid that is oxidized to form CYSTINE.
Experimental
Matched Synonyms: … (2S)-2-amino-3-mercaptopropanoic acid ... (2S)-2-amino-3-sulfanylpropanoic acid ... (S)-2-amino-3-mercaptopropanoic acid …
Matched Iupac: … (2S)-2-amino-3-sulfanylpropanoic acid …
Matched Salts cas: … 32443-99-5
A nucleoside analog with anti-hepatitis C virus (HCV) activity. Upon phosphorylation into its 5-triphosphate form, this metabolite inhibits viral RNA chain elongation and viral RNA-dependent RNA polymerase activity. This blocks viral production of HCV RNA and thus viral replication.
Experimental
Matched Synonyms: … 2'C-Me-C ... 2'-C-Mecytosin …
Matched Name: … 2'-C-methylcytidine …
Matched Iupac: … 4-amino-1-[(2R,3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)-3-methyloxolan-2-yl]-1,2-dihydropyrimidin-2- …
Matched Description: … Upon phosphorylation into its 5-triphosphate form, this metabolite inhibits viral RNA chain elongation …
2-deoxyglucose is predominantly used as a diagnostic agent in its radiolabelled form (fluorine-18 is used as the radiolabel). By using positron emission tomography (PET), radiolabelled 2-deoxyglucose can determine glucose metabolism, which is altered in diseases such as cardiovascular disease, tumors, and Alzheimer's disease. Therapeutically, 2-deoxyglucose is an investigational drug that...
Experimental
Investigational
Matched Synonyms: … 2-DG ... 2-deoxy-D-glucose ... 2-Deoxy-D-arabino-hexose …
Matched Name: … 2-deoxyglucose …
Matched Description: … approved indication for 2-deoxyglucose as a therapeutic agent. ... 2-deoxyglucose is predominantly used as a diagnostic agent in its radiolabelled form (fluorine-18 is ... Therapeutically, 2-deoxyglucose is an investigational drug that is being studied as an anticancer and …
Displaying drugs 7976 - 8000 of 11231 in total