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Displaying drugs 8001 - 8025 of 11231 in total
Vinylglycine is an irreversible inhibitor of aspartate aminotransferase.
Experimental
Matched Synonyms: … (2S)-2-amino-3-butenoic acid …
Matched Iupac: … (2S)-2-aminobut-3-enoic acid …
Experimental
Matched Iupac: … (2S,4R)-4-[(2S)-2-amino-5-[(E)-[amino(nitroamino)methylidene]amino]pentanamido]pyrrolidine-2-carboxamide …
Gedivumab is under investigation in clinical trial NCT01877785 (A Study of MHAA4549A to Assess Safety And Pharmacokinetics in Healthy Volunteers).
Investigational
AGA2115 is a humanized bispecific antibody neutralizing both sclerostin and Dickkopf-1. Developed by Angitia Biopharmaceuticals, AGA2115 is being investigated for the treatment of osteogenesis imperfect.
Investigational
Experimental
Matched Synonyms: … 2-deoxy-2-fluoro-beta-D-galactose ... 2-FLUORO-2-DEOXY-BETA-D-GALACTOPYRANOSE …
Matched Name: … 2-deoxy-2-fluoro-β-D-galactose …
AVP-21D9 is a fully human anthrax monoclonal antibody that is being investigated as an anthrax antitoxin.
Investigational
Experimental
Matched Synonyms: … 2-(2-Oxopropylthio)ethanesulfonate ... 2-[(2-Oxopropyl)sulfanyl]ethanesulfonic acid ... 2-ketopropyl-CoM …
Matched Name: … 2-oxopropyl-CoM …
Matched Iupac: … 2-[(2-oxopropyl)sulfanyl]ethane-1-sulfonic acid …
Experimental
Matched Iupac: … (cyclohexylmethoxy)(2-formylphenoxy)phosphinic acid …
NGX267 is a muscarinic agonist. It is developed for the treatment of Alzheimer’s disease and has shown the potential to both reduce symptoms and slow disease progression.
Investigational
Matched Iupac: … (2S)-2-ethyl-8-methyl-1-thia-4,8-diazaspiro[4.5]decan-3-one …
PTC299 is a novel, orally administered small-molecule designed to inhibit the production of vascular endothelial growth factor (VEGF) in tumors. Overexpression of VEGF plays a key role in multiple diseases including cancer and macular degeneration. PTC299 was discovered through PTC's GEMS technology by targeting the post-transcriptional processes that regulate VEGF...
Investigational
Matched Categories: … Heterocyclic Compounds, 2-Ring …
DiaPep 277 is a 24-mer laboratory-made peptide derived from Hsp60(437-460).
Investigational
Matched Iupac: … methylpentylidene]amino}-1-hydroxy-4-methylpentylidene]amino}-5-carbamimidamido-1-hydroxypentylidene] ... -2-amino-1-hydroxy-3-methylbutylidene]amino}-1-hydroxy-4-methylpentylidene]amino}-1-hydroxyethylidene ... }-1,3-dihydroxypropylidene]amino}-1-hydroxy-4-methylpentylidene]amino}-3-hydroxybutanoyl]pyrrolidin-2 ... -hydroxyethylidene]amino}-1-hydroxy-3-methylbutylidene]amino}-1-hydroxypropylidene]amino}-1-hydroxy-4- ... )-1-hydroxypropylidene]amino}-1-hydroxy-4-methylpentylidene]amino}-3-carboxy-1-hydroxypropylidene]amino …
Bamet-UD2 is a novel bile acid-platinum derivative.
Experimental
LY2334737 has been used in trials studying the treatment of Solid Tumor, Metastatic Tumor, and Malignant Solid Tumor.
Investigational
Matched Iupac: … N-{1-[(2R,4R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-2-oxo-1,2-dihydropyrimidin-4-yl ... }-2-propylpentanamide …
LY2811376 has been used in trials studying the basic science of Alzheimer's Disease.
Investigational
Matched Iupac: … (4S)-4-[2,4-difluoro-5-(pyrimidin-5-yl)phenyl]-4-methyl-5,6-dihydro-4H-1,3-thiazin-2-amine …
MVA-SARS-2-S is a COVID-19 vaccine candidate that contains a Modified Vaccinia Virus Ankara (MVA) vector expressing the SARS-CoV-2 spike protein . MVA is a highly attenuated poxvirus vector that has a high-level of biological safety due to its quality of being a non-replicating virus in mammalian hosts and is used...
Investigational
Matched Name: … MVA-SARS-2-S …
Matched Description: … expressing the SARS-CoV-2 spike protein[L30453]. ... MVA-SARS-2-S is a COVID-19 vaccine candidate that contains a Modified Vaccinia Virus Ankara (MVA) vector …
Investigational
OAV201 is a non-replicating, recombinant adeno-associated virus serotype 9 (AAV9) containing the human Methyl CpG Binding Protein 2B (MECP2B) cDNA under the control of a segment of the murine MECP2 promoter. It was first developed by Novartis and investigated for the treatment of Rett syndrome, but further investigation in clinical...
Investigational
ECT204 is an autologous T-cell therapy whereby T cells are genetically modified to target tumor-specific antigens.
Investigational
Experimental
Matched Synonyms: … 6-Azauridine-5'-monophosphate …
Matched Name: … 6-aza uridine 5'-monophosphate …
Matched Iupac: … {[(2R,3S,4R,5R)-5-(3,5-dioxo-2,3,4,5-tetrahydro-1,2,4-triazin-2-yl)-3,4-dihydroxyoxolan-2-yl]methoxy} …
Experimental
Matched Iupac: … 3-{3-[(1S,5S,6R,7S,9S,10S)-5,9-dimethyl-4-oxo-8-oxatetracyclo[7.2.1.1^{7,10}.0^{1,6}]tridec-2-en-5-yl …
Experimental
Amrubicin is a third-generation synthetic anthracycline currently in development for the treatment of small cell lung cancer. Pharmion licensed the rights to Amrubicin in November 2006. In 2002, Amrubicin was approved and launched for sale in Japan based on Phase 2 efficacy data in both SCLC and NSCLC. Since January...
Investigational
Matched Iupac: … (7S,9S)-9-acetyl-9-amino-7-{[(2S,4S,5R)-4,5-dihydroxyoxan-2-yl]oxy}-6,11-dihydroxy-5,7,8,9,10,12-hexahydrotetracene …
Matched Description: … In 2002, Amrubicin was approved and launched for sale in Japan based on Phase 2 efficacy data in both …
Triazavirin is a guanine nucleotide analog antiviral originally developed in Russia that has shown efficacy against influenza A and B, including the H5N1 strain.[A191709,A191625,A191916] It appears that Triazavirin has shown promise in reducing influenza disease severity and associated complications. Given the similarities between SARS-CoV-2 and H5N1, health officials are investigating...
Experimental
Matched Iupac: … 7-(methylsulfanyl)-3-nitro-1H,4H-[1,2,4]triazolo[3,2-c][1,2,4]triazin-4-one …
Matched Description: … as an option to combat SARS-CoV-2, the coronavirus responsible for COVID-19. ... [L12087] Given the similarities between SARS-CoV-2 and H5N1, health officials are investigating Triazavirin …
Investigational
Experimental
Matched Synonyms: … 7-methylguanosine 5'-(tetrahydrogen triphosphate) …
Matched Name: … 7-methyl-guanosine-5'-triphosphate …
Matched Iupac: … 2-amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-({[hydroxy({[hydroxy(phosphonooxy)phosphoryl]oxy})phosphoryl ... ]oxy}methyl)oxolan-2-yl]-7-methyl-6-oxo-6,9-dihydro-1H-purin-7-ium …
Displaying drugs 8001 - 8025 of 11231 in total