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Displaying drugs 801 - 825 of 997 in total
Investigational
Matched Synonyms: … isoform 1), disulfide with (85-glutamic acid) human-mus musculus monoclonal SHR-1316 .kappa. ... programmed death-ligand 1) (human-mus musculus monoclonal SHR-1316 .gamma.4-chain) fusion protein with ... Immunoglobulin G4 (52-glycine, 57-phenylalanine, 227-proline, 233-alanine, 234-alanine, 446-alanine), anti-(human
Matched Categories: … Amino Acids, Peptides, and Proteins …
Iodinated I-131 serum albumin is a radiopharmaceutical agent used for several diagnostic purposes, including the determination of body fluid volumes and the imaging of certain tissues.
Approved
Matched Synonyms: … Human albumin I-131 ... Human serum albumin I-131 ... Iodinated (131I) human serum albumin …
Matched Description: … radiopharmaceutical agent used for several diagnostic purposes, including the determination of body fluid volumes and
Investigational
Matched Synonyms: … Peptide YY human ... Peptide YY (human) ... Peptide YY human (1-36) …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Avalglucosidase alfa, or NeoGAA, is a drug for enzyme replacement therapy specifically designed for Pompe disease, a rare inherited neuromuscular disorder caused by the deficiency of the alpha-glucosidase (GAA) enzyme. GAA is an essential enzyme that hydrolyzes glycogen into free glucose for use in cellular functions. In Pompe disease, the...
Approved
Investigational
Matched Synonyms: … Neo-recombinant human acid alpha-glucosidase …
Matched Description: … , especially in smooth, cardiac, and skeletal muscle cells. ... muscle weakness, which leads to premature death and debilitating effects on people’s lives. ... In Pompe disease, the GAA enzyme is missing and patients are unable to properly break down glycogen, …
Matched Categories: … Enzymes and Coenzymes ... Alimentary Tract and Metabolism …
Sennosides (also known as senna glycoside or senna) is a medication used to treat constipation[FDA Label] and empty the large intestine before surgery. The medication is taken by mouth or via the rectum[FDA Label]. It typically begins working in minutes when given by rectum and within twelve hours when given...
Experimental
Matched Description: … also known as senna glycoside or senna) is a medication used to treat constipation[FDA Label][L771] and ... It typically begins working in minutes when given by rectum and within twelve hours when given by mouth ... laxative medication, has recently proven effective in inhibiting the ribonuclease H (RNase H) activity of human
Matched Mixtures name: … Senna and Docusate Sodium ... Senna and Docusate Sodium ... Sennosides and Docusate Sodium …
Matched Salts name: … Sennosides A and B …
Matched Categories: … Alimentary Tract and Metabolism ... Herbs and Natural Products …
Matched Products: … Humco Senna Powder ... Humco Senna Leaves …
Cepeginterferon alfa-2B is under investigation in clinical trial NCT01889433 (An Open-label Comparative Efficacy and Safety Study of Algeron (Cepeginterferon Alfa-2b) in Treatment-naive Patients With Chronic Hepatitis C).
Investigational
Matched Synonyms: … Pegylated human interferon A-2B …
Matched Description: … Cepeginterferon alfa-2B is under investigation in clinical trial NCT01889433 (An Open-label Comparative Efficacy and
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Eftansomatropin alfa (GX-H9) comprises a recombinant human growth hormone fused to hyFc, a synthetic hybrid Fc fragment. It is under investigation for the treatment of growth hormone deficiency.
Investigational
Matched Synonyms: … Somatotropin (human) fusion protein with immunoglobulin (synthetic hybrid fc fragment hyfc) …
Matched Description: … Eftansomatropin alfa (GX-H9) comprises a recombinant human growth hormone fused to hyFc, a synthetic …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Investigational
Matched Synonyms: … Adeno-associated viral 2/5 (AAV2/5) vector expressing the human KCNJ13 gene …
Investigational
Matched Name: … Humate-P …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Antithrombin gamma is under investigation in clinical trial NCT04182373 (KW-3357 Study in Patients With Early Onset Severe Preeclampsia).
Investigational
Matched Synonyms: … Antithrombin (human variant kw-3357) ... Human antithrombin-iii (atiii, serpin c1) expressed in fucosyl transferase-negative chinese hamster ovary …
Drotrecogin alfa is activated human protein C that is synthesized by recombinant DNA technology. It is a glycoprotein of approximately 55 kilodalton molecular weight, consisting of a heavy chain and a light chain linked by a disulfide bond. Drotrecogin alfa was withdrawn from the market after a major study indicated...
Approved
Investigational
Withdrawn
Matched Synonyms: … Blood coagulation factor XIV (human) ... Recombinant human activated protein C (rH-APC) …
Matched Description: … It is a glycoprotein of approximately 55 kilodalton molecular weight, consisting of a heavy chain and ... Drotrecogin alfa is activated human protein C that is synthesized by recombinant DNA technology. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes ... Blood and Blood Forming Organs …
The insulin-like growth factor II is a well-characterized neutral peptide believed to be secreted by the liver and to circulate in the blood. This factor presents effects related to growth regulation, insulin-like and mitogenic activities. To perform its biological activities, this growth factor can present some dependence to somatotropin. It...
Experimental
Matched Synonyms: … Human oligopeptide-24 ... Human insulin-like growth factor II ... Insulin-like growth factor II (human) …
Matched Description: … insulin-like growth factor II is a well-characterized neutral peptide believed to be secreted by the liver and ... This factor presents effects related to growth regulation, insulin-like and mitogenic activities. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Human recombinant alpha-L-iduronidase, 628 residues (mature form), produced by recombinant DNAtechnology in a Chinese hamster ovary cell line. Laronidase is a glycoprotein with a molecular weight of approximately 83 kD. The predicted amino acid sequence of the recombinant form, as well as the nucleotide sequence that encodes it, are identical...
Approved
Matched Synonyms: … Human Recombinant alpha-L-iduronidase …
Matched Description: … Human recombinant alpha-L-iduronidase, 628 residues (mature form), produced by recombinant DNAtechnology ... recombinant form, as well as the nucleotide sequence that encodes it, are identical to a polymorphic form of human
Matched Categories: … Enzymes and Coenzymes ... Alimentary Tract and Metabolism …
Investigational
Matched Synonyms: … Fully Human Igg1 Antibody Specific For Cd33 …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Col-Treg is an autologous T-cell therapy comprising type I regulatory T-cells specific for human type II collagen.
Investigational
Matched Synonyms: … Purified autologous type 1 regulatory T lymphocytes specific for human type II collagen …
Matched Description: … Col-Treg is an autologous T-cell therapy comprising type I regulatory T-cells specific for human type …
Somatorelin has been used in trials studying the treatment of Aging, Elderly, Sleep Disorders, Hormone Deficiency, and Mild Cognitive Impairment.
Investigational
Matched Synonyms: … SOMATOLIBERIN, HUMAN ... SOMATOLIBERIN (HUMAN) ... GROWTH HORMONE-RELEASING FACTOR (HUMAN) …
Matched Description: … been used in trials studying the treatment of Aging, Elderly, Sleep Disorders, Hormone Deficiency, and
Matched Categories: … Hypothalamic Hormones ... Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Cendakimab is a recombinant humanized anti-interleukin 13 (IL-13) monoclonal antibody.
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G1(240-ALANINE, 241-ALANINE), ANTI-(HUMAN INTERLEUKIN 13) (HUMAN-MUS MUSCULUS MONOCLONAL ... HUMANIZED ANTI-HUMAN IL-13 MONOCLONAL ANTIBODY ... RPC4046 .GAMMA.-1), DISULFIDE WITH HUMAN-MUS MUSCULUS MONOCLONAL RPC4046 .KAPPA.-1, DIMER …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Sargramostim is a human recombinant granulocyte macrophage colony-stimulating factor (GM-CSF) expressed in yeast. It is a glycoprotein that is 127 residues. Substitution of Leu23 leads to a difference from native protein.
Approved
Investigational
Matched Synonyms: … Recombinant human granulocyte-macrophage colony stimulating factor …
Matched Description: … Sargramostim is a human recombinant granulocyte macrophage colony-stimulating factor (GM-CSF) expressed …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Intercellular Signaling Peptides and Proteins …
Investigational
Matched Synonyms: … Human single domain antibody-like protein inhibitor of the chemokine receptor type 4 …
Investigational
Matched Synonyms: … Human elafin …
Glucagon is a 29 amino acid hormone used as a diagnostic aid in radiologic exams to temporarily inhibit the movement of the gastrointestinal tract and to treat severe hypoglycemia.[L7634,L7637,L7640,L7643,L8519] Glucagon raises blood sugar through activation of hepatic glucagon receptors, stimulating glycogenolysis and the release of glucose.[L7640,L7643] Glucagon was granted FDA...
Approved
Matched Synonyms: … Glucagon, human
Matched Description: … diagnostic aid in radiologic exams to temporarily inhibit the movement of the gastrointestinal tract and ... Glucagon raises blood sugar through activation of hepatic glucagon receptors, stimulating glycogenolysis and
Matched Categories: … Amino Acids, Peptides, and Proteins ... Sex Hormones and Insulins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Galsufase is a variant form of the polymorphic human enzyme N-acetylgalactosamine 4-sulfatase of recombinant DNA origin. Galsulfase is a glycoprotein with a molecular weight of approximately 56 kD. The recombinant protein is comprised of 495 amino acids and contains six asparagine-linked glycosylation sites, four of which carry a bis mannose-6-phosphate...
Approved
Investigational
Matched Synonyms: … N-acetylgalactosamine-4-sulfatase, recombinant human
Matched Description: … The recombinant protein is comprised of 495 amino acids and contains six asparagine-linked glycosylation ... Cys53 produces the catalytic amino acid residue Ca-formylglycine, which is required for enzyme activity and ... Galsufase is a variant form of the polymorphic human enzyme N-acetylgalactosamine 4-sulfatase of recombinant …
Matched Categories: … Alimentary Tract and Metabolism ... Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins ... Chondroitinases and Chondroitin Lyases …
Investigational
Matched Synonyms: … Anti-CEA sheep-human chimeric monoclonal antibody labeled w/iodine-131 (KAb201) …
Investigational
Matched Synonyms: … Human major histocompatibility complex (MHC) non-restricted T-cell line 104 …
Investigational
Matched Synonyms: … Recombinant human cerebral dopamine neurotrophic factor …
Displaying drugs 801 - 825 of 997 in total