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Displaying drugs 8351 - 8375 of 10632 in total
Adherex's biotechnology compound, ADH-1, targets N-cadherin, a protein present on certain tumor cells and established tumor blood vessels. ADH-1 is currently in clinical development in a combination program with a range of chemotherapeutic agents to investigate the synergistic effects noted in our preclinical models. At the end of 2006, the...
Investigational
Matched Synonyms: … l-cysteinamide, n-acetyl-l-cysteinyl-l-histidyl-l-alanyl-l-valyl-, cyclic (1-5)-disulfide …
Experimental
Matched Synonyms: … 2-(4-morpholinoanilino)-6-cyclohexylaminopurine …
Matched Iupac: … N6-cyclohexyl-N2-[4-(morpholin-4-yl)phenyl]-9H-purine-2,6-diamine …
Islatravir is under investigation in clinical trial NCT04233216 (Doravirine/islatravir (DOR/ISL) in Heavily Treatment-experienced (HTE) Participants for Human Immunodeficiency Virus Type 1 (HIV-1) Infection (MK-8591A-019)).
Investigational
Matched Synonyms: … 4'-ethynyl-2-fluoro-2'-deoxyadenosine …
Matched Iupac: … (2R,3S,5R)-5-(6-amino-2-fluoro-9H-purin-9-yl)-2-ethynyl-2-(hydroxymethyl)oxolan-3-ol …
Experimental
Matched Iupac: … [(2S,3R,4S,5R,6R)-2,5-dihydroxy-6-(hydroxymethyl)-4-(sulfooxy)oxan-3-yl]oxidanesulfonic acid …
Promestriene (3-propyl ethyl, 17B-methyl estradiol) has been used in trials studying the prevention of Hypospadias. It is a synthetic estrogen analog, which is used in topical estrogen therapy. Promestriene’s potential for treating vaginal atrophy symptoms associated with aromatase inhibitor treatment would be precluded if its minimal absorption leads to estrogen-like...
Investigational
Matched Description: … Promestriene (3-propyl ethyl, 17B-methyl estradiol) has been used in trials studying the prevention of …
Experimental
Matched Name: … N7-(5'-Phospho-alpha-ribosyl)-2-hydroxypurine …
Matched Iupac: … {[(2R,3S,4R,5S)-3,4-dihydroxy-5-(2-oxo-3,7-dihydro-2H-purin-7-yl)oxolan-2-yl]methoxy}phosphonic acid …
Experimental
Matched Iupac: … (2S)-2-[({[(2R,3S,4S,5S)-5-{[(2R,3R,4R)-5-{4-[(6R,6aS,7S)-3-amino-6,7-dimethyl-1-oxo-1H,2H,5H,6H,6aH, …
Experimental
Matched Name: … 2'-Monophosphoadenosine-5'-Diphosphoribose …
Matched Iupac: … (6R)-9-[(2R,3R,4R,5R)-4-hydroxy-5-({[hydroxy({[hydroxy({[(2R,3S,4R,5R)-3,4,5-trihydroxyoxolan-2-yl]methoxy ... })phosphoryl]oxy})phosphoryl]oxy}methyl)-3-(phosphonooxy)oxolan-2-yl]-2,3,6,9-tetrahydro-1H-purin-6-aminium …
Experimental
Matched Name: … N-PYRIDOXYL-D-GLUTAMIC ACID-5'-MONOPHOSPHATE …
Matched Iupac: … (2R)-2-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]pentanedioic acid …
Experimental
Matched Name: … N6-ISOPENTENYL-ADENOSINE-5'-MONOPHOSPHATE …
Matched Iupac: … {[(2R,3S,4R,5R)-3,4-dihydroxy-5-{6-[(3-methylbutyl)amino]-9H-purin-9-yl}oxolan-2-yl]methoxy}phosphonic …
Experimental
Investigational
Experimental
Matched Iupac: … chromium(3+) 2-hydroxypropane-1,2,3-tricarboxylate …
Experimental
Matched Name: … 7-methyl-7,8-dihydroguanosine-5'-diphosphate …
Matched Iupac: … [({[(2R,3S,4R,5R)-3,4-dihydroxy-5-(6-hydroxy-2-imino-7-methyl-3,7,8,9-tetrahydro-2H-purin-9-yl)oxolan …
Experimental
Matched Name: … 2-[(2-methoxy-5-methylphenoxy)methyl]pyridine …
Matched Iupac: … 2-[(2-methoxy-5-methylphenoxy)methyl]pyridine …
Ginisortamab is under investigation in clinical trial NCT04393298 (A Study to Assess the Safety, Pharmacokinetics and Anti Tumor Activity of UCB6114 Administered Intravenously to Participants With Advanced Solid Tumors).
Investigational
Matched Synonyms: … Immunoglobulin g4 (232-proline), anti-(human gremlin 1) (human monoclonal ucb6114 .gamma.4-chain), disulfide …
Garenoxacin, a quinolone antibiotic, is being investigated for the treatment of gram-positive and gram-negative bacterial infections.
Investigational
Matched Iupac: … 1-cyclopropyl-8-(difluoromethoxy)-7-[(1R)-1-methyl-2,3-dihydro-1H-isoindol-5-yl]-4-oxo-1,4-dihydroquinoline ... -3-carboxylic acid …
Experimental
Matched Name: … N-Hydroxy-1-(4-Methoxyphenyl)Sulfonyl-4-Benzyloxycarbonyl-Piperazine-2-Carboxamide …
Matched Iupac: … benzyl (3R)-3-(hydroxycarbamoyl)-4-(4-methoxybenzenesulfonyl)piperazine-1-carboxylate …
Delpacibart is a humanized, bispecific, bivalent monoclonal antibody against coagulation factor 9.
Investigational
Experimental
Matched Iupac: … {[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-2-({[({[(3R)-3-({2-[(2-{[(2E)-3-(3,4-dihydroxy-5-methoxyphenyl ... }oxy)(hydroxy)phosphoryl]oxy}methyl)-4-hydroxyoxolan-3-yl]oxy}phosphonic acid ... )prop-2-enoyl]sulfanyl}ethyl)carbamoyl]ethyl}carbamoyl)-3-hydroxy-2,2-dimethylpropoxy](hydroxy)phosphoryl …
Experimental
Matched Name: … 4-iodo-acetamido phenylboronic acid …
Matched Iupac: … [3-(2-iodoacetamido)phenyl]boronic acid …
Experimental
Matched Name: … (2R)-2-PHENYL-N-PYRIDIN-4-YLBUTANAMIDE …
Matched Iupac: … (2R)-2-phenyl-N-(pyridin-4-yl)butanamide …
Experimental
Matched Name: … N-[(4-methoxyphenyl)sulfonyl]-D-alanine …
Matched Iupac: … (2R)-2-(4-methoxybenzenesulfonamido)propanoic acid …
Experimental
Matched Name: … Cp-166572, 2-Hydroxymethyl-4-(4-N,N-Dimethylaminosulfonyl-1-Piperazino)-Pyrimidine …
Matched Iupac: … 4-[2-(hydroxymethyl)pyrimidin-4-yl]-N,N-dimethylpiperazine-1-sulfonamide …
Burfiralimab is under investigation in clinical trial NCT06306339 (A Study to Assess the Efficacy and Safety of Burfiralimab (Hzvsf-v13) and DMRD (Disease-modifying Antirheumatic Drug)).
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G4, ANTI-(HUMAN VIMENTIN) (HUMAN-MUS MUSCULUS .GAMMA.4-CHAIN), DISULFIDE WITH HUMAN-MUS …
Experimental
Matched Synonyms: … Glyme 5
Displaying drugs 8351 - 8375 of 10632 in total