Displaying drugs 8801 - 8825 of 9061 in total
Nafamostat
Nafamostat is a synthetic serine protease inhibitor that is commonly formulated with hydrochloric acid due to its basic properties. It has been used in trials studying the prevention of Liver Transplantation and Postreperfusion Syndrome. The use of nafamostat in Asian countries is approved as an anticoagulant therapy for patients undergoing...
Investigational
Matched Synonyms: … p-Guanidinobenzoic acid ester with 6-hydroxy-2-naphthamidine …
Matched Iupac: … 6-carbamimidoylnaphthalen-2-yl 4-carbamimidamidobenzoate …
Matched Salts cas: … 82956-11-4 …
Matched Iupac: … 6-carbamimidoylnaphthalen-2-yl 4-carbamimidamidobenzoate …
Matched Salts cas: … 82956-11-4 …
Suratadenoturev
Suratadenoturev is a gene-modified oncolytic adenovirus expressing the telomerase reverse transcriptase gene.
Investigational
7-methyl-guanosine-5'-triphosphate-5'-guanosine
Experimental
Matched Iupac: … -2-yl]-7-methyl-6-oxo-6,7-dihydro-3H-9lambda5-purin-9-ylium ... 2-amino-9-[(2R,3R,4S,5R)-5-({[({[({[(2R,3S,4R,5R)-5-(2-amino-6-oxo-6,9-dihydro-3H-purin-9-yl)-3,4-dihydroxyoxolan ... -2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)(hydroxy)phosphoryl]oxy}methyl)-3,4-dihydroxyoxolan …
Sparteine
Sparteine is a plant alkaloid derived from Cytisus scoparius and Lupinus mutabilis which may chelate calcium and magnesium. It is a sodium channel blocker, so it falls in the category of class 1a antiarrhythmic agents. Sparteine is not currently FDA-approved for human use, and its salt, sparteine sulfate, is one...
Experimental
Withdrawn
Matched Categories: … Heterocyclic Compounds, 2-Ring …
2-METHYLTHIO-N6-ISOPENTENYL-ADENOSINE-5'-MONOPHOSPHATE
Experimental
Matched Name: … 2-METHYLTHIO-N6-ISOPENTENYL-ADENOSINE-5'-MONOPHOSPHATE …
Matched Iupac: … {[(2R,3S,4R,5R)-3,4-dihydroxy-5-{6-[(3-methylbutyl)amino]-2-(methylsulfanyl)-9H-purin-9-yl}oxolan-2-yl …
Matched Iupac: … {[(2R,3S,4R,5R)-3,4-dihydroxy-5-{6-[(3-methylbutyl)amino]-2-(methylsulfanyl)-9H-purin-9-yl}oxolan-2-yl …
Verubecestat
Verubecestat is under investigation for the treatment of Alzheimer's Disease, Prodromal Alzheimer's disease, and Amnestic Mild Cognitive Impairment.
Verubecestat is Merck’s investigational oral β-site amyloid precursor protein cleaving enzyme (BACE1 or β secretase) inhibitor. In July 2013, Merck announced positive results for Phase Ib trials of Verubecestat. In the study,...
Investigational
Matched Iupac: … N-{3-[(5R)-3-amino-2,5-dimethyl-1,1-dioxo-5,6-dihydro-2H-1lambda6,2,4-thiadiazin-5-yl]-4-fluorophenyl ... }-5-fluoropyridine-2-carboxamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Fasiglifam
Fasiglifam has been used in trials studying the treatment of Chronic Kidney Disease, Type 2 Diabetes Mellitus, and Diabetes Mellitus, Type 2.
Investigational
Matched Iupac: … 2-[(3S)-6-{[4'-(3-methanesulfonylpropoxy)-2',6'-dimethyl-[1,1'-biphenyl]-3-yl]methoxy}-2,3-dihydro-1- …
Matched Description: … Mellitus, and Diabetes Mellitus, Type 2. ... Fasiglifam has been used in trials studying the treatment of Chronic Kidney Disease, Type 2 Diabetes …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Description: … Mellitus, and Diabetes Mellitus, Type 2. ... Fasiglifam has been used in trials studying the treatment of Chronic Kidney Disease, Type 2 Diabetes …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Glutathionylspermidine
Experimental
Matched Iupac: … (2S)-2-amino-4-{[(1R)-1-{[({3-[(4-aminobutyl)amino]propyl}-C-hydroxycarbonimidoyl)methyl]-C-hydroxycarbonimidoyl ... }-2-sulfanylethyl]-C-hydroxycarbonimidoyl}butanoic acid …
Capric acid
Decanoic acid is a solid. This compound belongs to the straight chain fatty acids. These are fatty acids with a straight aliphatic chain. The proteins that decanoic acid targets include furin, octanoyltransferase, 3-oxoacyl-[acyl-carrier-protein] synthase 1, peptostreptococcal albumin-binding protein, and putative uncharacterized protein tcp14.
Experimental
Matched Synonyms: … 1-nonanecarboxylic acid …
Matched Description: … decanoic acid targets include furin, octanoyltransferase, 3-oxoacyl-[acyl-carrier-protein] synthase 1, …
Matched Description: … decanoic acid targets include furin, octanoyltransferase, 3-oxoacyl-[acyl-carrier-protein] synthase 1, …
Bisindolylmaleimide VIII
Experimental
Matched Iupac: … 3-[1-(3-aminopropyl)-1H-indol-3-yl]-4-(1-methyl-1H-indol-3-yl)-2,5-dihydro-1H-pyrrole-2,5-dione …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …
Moxalactam (hydrolyzed)
Experimental
Matched Iupac: … (2R)-2-{carboxy[(2S)-2-carboxy-2-(4-hydroxyphenyl)acetamido]methoxymethyl}-5-methylidene-5,6-dihydro- ... 2H-1,3-oxazine-4-carboxylic acid …
Garenoxacin
Garenoxacin, a quinolone antibiotic, is being investigated for the treatment of gram-positive and gram-negative bacterial infections.
Investigational
Matched Iupac: … 1-cyclopropyl-8-(difluoromethoxy)-7-[(1R)-1-methyl-2,3-dihydro-1H-isoindol-5-yl]-4-oxo-1,4-dihydroquinoline …
Matched Salts cas: … 223652-90-2 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Salts cas: … 223652-90-2 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Dithiazanine
Dithiazanine is a highly potent anthelmintic, introduced in 1959 for the treatment of strongyloid worms and whipworms. However, its use is severely limited due to its toxicity. Dithiazanine iodide was associated with eight fatal cases of severe acidosis and shock between 1961 and 1964. Dithiazanine iodide has been withdrawn from...
Vet approved
Withdrawn
Matched Iupac: … 3-ethyl-2-[5-(3-ethyl-2,3-dihydro-1,3-benzothiazol-2-ylidene)penta-1,3-dien-1-yl]-1,3-benzothiazol-3- …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …
Lecozotan
Lecozotan has been used in trials studying the treatment of Alzheimer Disease.
Investigational
Matched Iupac: … 4-cyano-N-[(2R)-2-[4-(2,3-dihydro-1,4-benzodioxin-5-yl)piperazin-1-yl]propyl]-N-(pyridin-2-yl)benzamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Laninamivir
Laninamivir has been used in trials studying the treatment of Influenza.
Investigational
Matched Iupac: … (2R,3R,4S)-4-carbamimidamido-2-[(1R,2R)-2,3-dihydroxy-1-methoxypropyl]-3-acetamido-3,4-dihydro-2H-pyran …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Taniborbactam
Taniborbactam is under investigation in clinical trial NCT03840148 (Safety and Efficacy Study of Cefepime/vnrx-5133 in Patients With Complicated Urinary Tract Infections).
Investigational
Matched Iupac: … (3R)-2-hydroxy-3-{2-[(1r,4r)-4-[(2-aminoethyl)amino]cyclohexyl]acetamido}-3,4-dihydro-2H-1,2-benzoxaborinine …
Mesobiliverdin IV alpha
Experimental
Matched Iupac: … 3-[(2Z)-2-{[4-(2-carboxyethyl)-5-{[(2Z)-3-ethyl-4-methyl-5-oxo-2,5-dihydro-1H-pyrrol-2-ylidene]methyl ... }-3-methyl-1H-pyrrol-2-yl]methylidene}-5-{[(2Z)-3-ethyl-4-methyl-5-oxo-2,5-dihydro-1H-pyrrol-2-ylidene ... ]methyl}-3-methyl-2H-pyrrol-4-yl]propanoic acid …
P1-(5'-Adenosyl)P5-(5'-(3'azido-3'-Deoxythymidyl))Pentaphosphate
Experimental
Matched Iupac: … -2-yl]-5-methyl-2-oxo-1,2-dihydropyrimidin-4-olate ... 1-[(2R,4S,5S)-5-[({[({[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl phosphonato ... }oxy)(oxido)phosphoryl]oxy}(hydroxy)phosphoryl phosphonato)oxy](oxido)phosphoryl}oxy)methyl]-4-azidooxolan …
m-Hydroxyhippuric acid
Experimental
Matched Synonyms: … 2-[(3-hydroxyphenyl)formamido]acetic acid …
Matched Iupac: … 2-[(3-hydroxyphenyl)formamido]acetic acid …
Matched Iupac: … 2-[(3-hydroxyphenyl)formamido]acetic acid …
Emetonium iodide
Experimental
Matched Synonyms: … (2-benzhydryloxyethyl)diethyl-methylammonium iodide …
Matched Iupac: … [2-(diphenylmethoxy)ethyl]diethylmethylazanium iodide …
Matched Categories: … (2-benzhydryloxyethyl)diethyl-methylammonium iodide …
Matched Iupac: … [2-(diphenylmethoxy)ethyl]diethylmethylazanium iodide …
Matched Categories: … (2-benzhydryloxyethyl)diethyl-methylammonium iodide …
dATP
Experimental
Matched Synonyms: … 2'-Deoxyadenosine 5'-triphosphate …
Matched Iupac: … ({[({[(2R,3S,5R)-5-(6-amino-9H-purin-9-yl)-3-hydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Iupac: … ({[({[(2R,3S,5R)-5-(6-amino-9H-purin-9-yl)-3-hydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
DADLE
A delta-selective opioid (ANALGESICS, OPIOID). It can cause transient depression of mean arterial blood pressure and heart rate.
Experimental
Matched Iupac: … (2R)-2-[(2S)-2-{2-[(2R)-2-[(2S)-2-amino-3-(4-hydroxyphenyl)propanamido]propanamido]acetamido}-3-phenylpropanamido ... ]-4-methylpentanoic acid …
norUrsodeoxycholic acid
norUrsodeoxycholic acid is under investigation in clinical trial NCT03872921 (Norursodeoxycholic Acid vs Placebo in PSC).
Investigational
Matched Iupac: … 3bR,4S,5aS,7R,9aS,9bS,11aR)-4,7-dihydroxy-9a,11a-dimethyl-hexadecahydro-1H-cyclopenta[a]phenanthren-1- …
Hiltonol
Investigational
Matched Synonyms: … 5'-cytidylic acid, homopolymer, complex with 5'-inosinic acid homopolymer (1:1), compd. with cellulose ... 5'-inosinic acid, homopolymer, complex with 5'-cytidylic acid homopolymer (1:1), compd. with cellulose …
Displaying drugs 8801 - 8825 of 9061 in total