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Displaying drugs 9001 - 9025 of 11731 in total
Guanosine-5'-Diphosphate-Rhamnose
Experimental
Matched Name: … Guanosine-5'-Diphosphate-Rhamnose …
Matched Iupac: … {[(2R,3S,4R,5R)-5-(2-amino-6-oxo-6,9-dihydro-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}({[hydroxy ... ({[(2R,3S,4S,5S,6R)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy})phosphoryl]oxy})phosphinic acid …
Matched Iupac: … {[(2R,3S,4R,5R)-5-(2-amino-6-oxo-6,9-dihydro-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}({[hydroxy ... ({[(2R,3S,4S,5S,6R)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy})phosphoryl]oxy})phosphinic acid …
2-Aminothiazoline
Experimental
Matched Name: … 2-Aminothiazoline …
Matched Iupac: … 4,5-dihydro-1,3-thiazol-2-amine …
Matched Iupac: … 4,5-dihydro-1,3-thiazol-2-amine …
B-2-Octylglucoside
Experimental
Matched Name: … B-2-Octylglucoside …
Matched Iupac: … (2R,3R,4S,5S,6R)-6-(hydroxymethyl)-3-(octyloxy)oxane-2,4,5-triol …
Matched Iupac: … (2R,3R,4S,5S,6R)-6-(hydroxymethyl)-3-(octyloxy)oxane-2,4,5-triol …
Prostaglandin G2
A cyclic endoperoxide intermediate produced by the action of CYCLOOXYGENASE on ARACHIDONIC ACID. It is further converted by a series of specific enzymes to the series 2 prostaglandins. [PubChem]
Experimental
Matched Iupac: … (5Z)-7-[(1R,4S,5R,6R)-6-[(1E,3S)-3-hydroperoxyoct-1-en-1-yl]-2,3-dioxabicyclo[2.2.1]heptan-5-yl]hept- ... 5-enoic acid …
Matched Description: … It is further converted by a series of specific enzymes to the series 2 prostaglandins. [PubChem] …
Matched Description: … It is further converted by a series of specific enzymes to the series 2 prostaglandins. [PubChem] …
2'-C-methylcytidine
A nucleoside analog with anti-hepatitis C virus (HCV) activity. Upon phosphorylation into its 5-triphosphate form, this metabolite inhibits viral RNA chain elongation and viral RNA-dependent RNA polymerase activity. This blocks viral production of HCV RNA and thus viral replication.
Experimental
Matched Synonyms: … 2'C-Me-C ... 2'-C-Mecytosin …
Matched Name: … 2'-C-methylcytidine …
Matched Iupac: … 4-amino-1-[(2R,3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)-3-methyloxolan-2-yl]-1,2-dihydropyrimidin-2- …
Matched Description: … Upon phosphorylation into its 5-triphosphate form, this metabolite inhibits viral RNA chain elongation …
Matched Name: … 2'-C-methylcytidine …
Matched Iupac: … 4-amino-1-[(2R,3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)-3-methyloxolan-2-yl]-1,2-dihydropyrimidin-2- …
Matched Description: … Upon phosphorylation into its 5-triphosphate form, this metabolite inhibits viral RNA chain elongation …
UDP-alpha-D-xylose
The decarboxylation product of UDPglucuronic acid, which is used for formation of the xylosides of seryl hydroxyl groups in mucoprotein synthesis. Also forms plant xylans.
Experimental
Matched Synonyms: … Uridine-5'-diphosphate-xylopyranose …
Matched Iupac: … {[(2R,3S,4R,5R)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}({[hydroxy ... ({[(2R,3R,4S,5R)-3,4,5-trihydroxyoxan-2-yl]oxy})phosphoryl]oxy})phosphinic acid …
Matched Iupac: … {[(2R,3S,4R,5R)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}({[hydroxy ... ({[(2R,3R,4S,5R)-3,4,5-trihydroxyoxan-2-yl]oxy})phosphoryl]oxy})phosphinic acid …
Desfesoterodine
Desfesoterodine is a metabolite of tolterodine.
Experimental
Matched Synonyms: … 5-Hydroxymethyltolterodine …
Matched Iupac: … 2-[(1R)-3-[bis(propan-2-yl)amino]-1-phenylpropyl]-4-(hydroxymethyl)phenol …
Matched Iupac: … 2-[(1R)-3-[bis(propan-2-yl)amino]-1-phenylpropyl]-4-(hydroxymethyl)phenol …
Prostaglandin B2
Experimental
Matched Iupac: … (5Z)-7-{2-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-5-oxocyclopent-1-en-1-yl}hept-5-enoic acid …
2-Dehydropantoate
Experimental
Matched Name: … 2-Dehydropantoate …
Matched Iupac: … 4-hydroxy-3,3-dimethyl-2-oxobutanoic acid …
Matched Iupac: … 4-hydroxy-3,3-dimethyl-2-oxobutanoic acid …
LY2181308
LY2181308 is investigated in clinical trials for treating solid tumors. LY2181308 is a solid. LY2181308 is directed against a molecular target called survivin. LY2181308 is known to target baculoviral IAP repeat-containing protein 5. LY2181308 is an anti-sense oligonucleotide that potently downregulated survivin expression in human cancer cells derived from lung,...
Investigational
Matched Description: … LY2181308 is known to target baculoviral IAP repeat-containing protein 5. …
LY2275796
LY2275796 is a second-generation antisense anti-cancer drug candidate for clinical development. LY2275796 targets eukaryotic initiation factor- 4E (eIF-4E), a protein involved in the translation of key growth and survival factors that drive tumor progression, angiogenesis and metastases.
Investigational
LY2828360
LY2828360 is under investigation in clinical trial NCT01319929 (A Study of LY2828360 in Patients With Osteoarthritic Knee Pain).
Investigational
Matched Iupac: … 8-(2-chlorophenyl)-2-methyl-6-(4-methylpiperazin-1-yl)-9-(oxan-4-yl)-9H-purine …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
BDBM249432
Investigational
Purine Riboside-5'-Monophosphate
Experimental
Matched Name: … Purine Riboside-5'-Monophosphate …
Matched Iupac: … {[(2R,3S,4R,5R)-3,4-dihydroxy-5-(9H-purin-9-yl)oxolan-2-yl]methoxy}phosphonic acid …
Matched Iupac: … {[(2R,3S,4R,5R)-3,4-dihydroxy-5-(9H-purin-9-yl)oxolan-2-yl]methoxy}phosphonic acid …
N-methyl-1-(2-thiophen-2-ylphenyl)methanamine
Experimental
Matched Name: … N-methyl-1-(2-thiophen-2-ylphenyl)methanamine …
Matched Iupac: … methyl({[2-(thiophen-2-yl)phenyl]methyl})amine …
Matched Iupac: … methyl({[2-(thiophen-2-yl)phenyl]methyl})amine …
IMIDAZO[2,1-A]ISOQUINOLINE-2-CARBOHYDRAZIDE
Experimental
Matched Name: … IMIDAZO[2,1-A]ISOQUINOLINE-2-CARBOHYDRAZIDE …
Matched Iupac: … imidazo[2,1-a]isoquinoline-2-carbohydrazide …
Matched Iupac: … imidazo[2,1-a]isoquinoline-2-carbohydrazide …
4-(2-methoxyethoxy)-6-methylpyrimidin-2-amine
Experimental
Matched Name: … 4-(2-methoxyethoxy)-6-methylpyrimidin-2-amine …
Matched Iupac: … 4-(2-methoxyethoxy)-6-methylpyrimidin-2-amine …
Matched Iupac: … 4-(2-methoxyethoxy)-6-methylpyrimidin-2-amine …
Bafilomycin B1
Experimental
Matched Iupac: … (2R,4R,5S,6R)-2-hydroxy-2-[(2S,3R,4S)-3-hydroxy-4-[(3S,4Z,6Z,9S,10S,11R,12Z,14E)-10-hydroxy-3,15-dimethoxy ... -2-yl)oxan-4-yl (2E)-3-[(2-hydroxy-5-oxocyclopent-1-en-1-yl)carbamoyl]prop-2-enoate ... -7,9,11,13-tetramethyl-16-oxo-1-oxacyclohexadeca-4,6,12,14-tetraen-2-yl]pentan-2-yl]-5-methyl-6-(propan …
RRx-001
RRx-001 has been used in trials studying the treatment of Lymphomas, Brain Metastases, Cholangiocarcinoma, Colorectal Neoplasms, and Malignant Solid Tumor, among others.
Investigational
Matched Iupac: … 2-bromo-1-(3,3-dinitroazetidin-1-yl)ethan-1-one …
2-(2-METHYLPHENYL)-1H-INDOLE-6-CARBOXIMIDAMIDE
Experimental
Matched Name: … 2-(2-METHYLPHENYL)-1H-INDOLE-6-CARBOXIMIDAMIDE …
Matched Iupac: … 2-(2-methylphenyl)-1H-indole-6-carboximidamide …
Matched Iupac: … 2-(2-methylphenyl)-1H-indole-6-carboximidamide …
methyl (1R,2S)-2-(hydroxycarbamoyl)-1-{4-[(2-methylquinolin-4-yl)methoxy]benzyl}cyclopropanecarboxylate
Experimental
Matched Name: … methyl (1R,2S)-2-(hydroxycarbamoyl)-1-{4-[(2-methylquinolin-4-yl)methoxy]benzyl}cyclopropanecarboxylate …
Matched Iupac: … methyl (1R,2S)-2-(hydroxycarbamoyl)-1-({4-[(2-methylquinolin-4-yl)methoxy]phenyl}methyl)cyclopropane- …
Matched Iupac: … methyl (1R,2S)-2-(hydroxycarbamoyl)-1-({4-[(2-methylquinolin-4-yl)methoxy]phenyl}methyl)cyclopropane- …
(1R)-1,2,2-trimethylpropyl (R)-methylphosphinate
Experimental
Matched Iupac: … (2R)-3,3-dimethylbutan-2-yl methylphosphinate …
Incadronic acid
Incadronate, or YM-175, is a nitrogen containing bisphosphonate. Along with being investigated to treat hypercalcemia of malignancy, it has also been investigated in the treatment of myeloma, leukemia, and other cancers.[A14426,A14431,A14427,A202769]
Incadronic acid was first described in the literature in 1991.
Experimental
Hexanoyl-CoA
Experimental
Matched Iupac: … {[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-2-({[({[(3R)-3-[(2-{[2-(hexanoylsulfanyl)ethyl]carbamoyl}ethyl ... -3-yl]oxy}phosphonic acid ... )carbamoyl]-3-hydroxy-2,2-dimethylpropoxy](hydroxy)phosphoryl}oxy)(hydroxy)phosphoryl]oxy}methyl)-4-hydroxyoxolan …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Displaying drugs 9001 - 9025 of 11731 in total