Displaying drugs 9376 - 9400 of 9807 in total
Mirococept
Mirococept (APT070) is a complement inhibitor currently under development for treatment of rheumatoid arthritis and I/RI. It is a truncated form of the human Complement Receptor 1 (CR1) linked to a unique Prodaptin™ construct that regulates the over-production of complement at the cell surface, which occurs in inflammation. It consists...
Investigational
Matched Description: … It is a truncated form of the human Complement Receptor 1 (CR1) linked to a unique Prodaptin™ construct ... It consists of the first three short consensus domains of human complement receptor 1 (CR1), manufactured …
Toralizumab
Toralizumab is under investigation in clinical trial NCT03605927 (CD40-L Blockade for Prevention of Acute Graft-versus-host Disease).
Investigational
Recombinant human placental growth factor (PLGF-131)
Investigational
Medetomidine
Medetomidine is a synthetic compound used as a surgical anesthetic and analgesic. It is normally found as its hydrochloride salt, medetomidine hydrochloride. Medetomidine is an intravenously available alpha-2 adrenergic agonist. The drug has been developed by Orion Pharma. In the United States, it is currently approved for its veterinary use...
Experimental
Vet approved
Matched Iupac: … 5-[1-(2,3-dimethylphenyl)ethyl]-1H-imidazole …
Matched Description: … Medetomidine is an intravenously available alpha-2 adrenergic agonist. …
Matched Salts cas: … 86347-15-1 …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Adrenergic alpha-2 Receptor Agonists …
Matched Description: … Medetomidine is an intravenously available alpha-2 adrenergic agonist. …
Matched Salts cas: … 86347-15-1 …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Adrenergic alpha-2 Receptor Agonists …
Carlumab
Carlumab has been used in trials studying the treatment of Cancer and Prostate Cancer.
Investigational
Withdrawn
Matched Synonyms: … Human monoclonal antibody targeting CC-chemokine ligand 2 (CNTO 888) …
Simlukafusp alfa
RO6874281 is under investigation in clinical trial NCT03193190 (A Study of Multiple Immunotherapy-based Treatment Combinations in Participants With Metastatic Pancreatic Ductal Adenocarcinoma (Morpheus-pancreatic Cancer)).
Investigational
Matched Synonyms: … Anti-fap/interleukin-2 fusion protein ro6874281 …
Cholesteryl chloride
Cholesteryl chloride, also known as 3-chlorocholest-5-ene, is an organochloride derivative of cholesterol. It is presented as a liquid crystal that forms clockwise liquid crystals.
Experimental
Matched Iupac: … (1R,3aS,3bS,7S,9aR,9bS,11aR)-7-chloro-9a,11a-dimethyl-1-[(2R)-6-methylheptan-2-yl]-1H,2H,3H,3aH,3bH,4H …
Thymidine 5'-triphosphate
Experimental
Matched Synonyms: … 2'-deoxythymidine triphosphate …
Matched Iupac: … -2-yl]methoxy})phosphoryl]oxy})phosphoryl]oxy}phosphonic acid ... {[hydroxy({[hydroxy({[(2R,3S,5R)-3-hydroxy-5-(5-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)oxolan …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Iupac: … -2-yl]methoxy})phosphoryl]oxy})phosphoryl]oxy}phosphonic acid ... {[hydroxy({[hydroxy({[(2R,3S,5R)-3-hydroxy-5-(5-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)oxolan …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Arginine PCA
Experimental
Matched Synonyms: … L-arginine L-2-pyrrolidone-5-carboxylate …
Matched Iupac: … (2S)-2-amino-5-carbamimidamidopentanoic acid; (2S)-5-oxopyrrolidine-2-carboxylic acid …
Matched Iupac: … (2S)-2-amino-5-carbamimidamidopentanoic acid; (2S)-5-oxopyrrolidine-2-carboxylic acid …
3-METHOXY-6-[4-(3-METHYLPHENYL)-1-PIPERAZINYL]PYRIDAZINE
Experimental
Matched Name: … 3-METHOXY-6-[4-(3-METHYLPHENYL)-1-PIPERAZINYL]PYRIDAZINE …
Matched Iupac: … 3-methoxy-6-[4-(3-methylphenyl)piperazin-1-yl]pyridazine …
Matched Iupac: … 3-methoxy-6-[4-(3-methylphenyl)piperazin-1-yl]pyridazine …
Recombinant human palmitoyl protein thioesterase-1
Investigational
Matched Name: … Recombinant human palmitoyl protein thioesterase-1 …
Olesoxime
Olesoxime is a cholesterol-like small molecule that has demonstrated a remarkable neuroprotective profile in a battery of both in vitro and in vivo preclinical models. For example, it has demonstrated the ability to prevent neurodegeneration, enhance nerve function and accelerate neuroregeneration following nerve trauma.[A3282,A253233]
Investigational
Matched Iupac: … N-[(1R,3aS,3bS,7E,9aR,9bS,11aR)-9a,11a-dimethyl-1-[(2R)-6-methylheptan-2-yl]-1H,2H,3H,3aH,3bH,4H,5H,7H ... ,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-7-ylidene]hydroxylamine …
Volociximab
Investigational
Ragifilimab
Ragifilimab is under investigation in clinical trial NCT04225039 (Anti-gitr/anti-pd1/stereotactic Radiosurgery, in Recurrent Glioblastoma).
Investigational
Matched Synonyms: … anti-(human tumor necrosis factor receptor tnfrsf18) (human-mus musculus monoclonal incagn01876.gamma.1- …
Zalifrelimab
Zalifrelimab is under investigation in clinical trial NCT03894215 (Phase 2 Study of Anti-pd-1 Independently or in Combination With Anti-ctla-4 in Second-line Cervical Cancer).
Investigational
Matched Description: … Zalifrelimab is under investigation in clinical trial NCT03894215 (Phase 2 Study of Anti-pd-1 Independently …
Onfekafusp alfa
Onfekafusp alfa is under investigation in clinical trial NCT02938299 (Neoadjuvant L19IL2/L19TNF- Pivotal Study).
Investigational
Depelestat
Investigational
2-Amino-4-(Hydroxymethyl-Phosphinyl)Butanoic Acid
Experimental
Matched Name: … 2-Amino-4-(Hydroxymethyl-Phosphinyl)Butanoic Acid …
Matched Iupac: … (2R)-2-amino-4-[hydroxy(methyl)phosphoryl]butanoic acid …
Matched Iupac: … (2R)-2-amino-4-[hydroxy(methyl)phosphoryl]butanoic acid …
Guanosine 5'-diphosphate 2':3'-cyclic monophosphate
Experimental
Matched Name: … Guanosine 5'-diphosphate 2':3'-cyclic monophosphate …
Matched Iupac: … [({[(3aR,4R,6R,6aR)-6-(2-amino-6-oxo-6,9-dihydro-3H-purin-9-yl)-2-hydroxy-2-oxo-tetrahydro-2H-2lambda5 …
Matched Iupac: … [({[(3aR,4R,6R,6aR)-6-(2-amino-6-oxo-6,9-dihydro-3H-purin-9-yl)-2-hydroxy-2-oxo-tetrahydro-2H-2lambda5 …
Vitamin B6 Complexed with 2-Amino-Pentanoic Acid
Experimental
Matched Name: … Vitamin B6 Complexed with 2-Amino-Pentanoic Acid …
Matched Iupac: … (2S)-2-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]pentanoic acid …
Matched Iupac: … (2S)-2-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]pentanoic acid …
N-(2-Aminoethyl)-5-Chloroisoquinoline-8-Sulfonamide
Experimental
Matched Name: … N-(2-Aminoethyl)-5-Chloroisoquinoline-8-Sulfonamide …
Matched Iupac: … N-(2-aminoethyl)-5-chloroisoquinoline-8-sulfonamide …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Iupac: … N-(2-aminoethyl)-5-chloroisoquinoline-8-sulfonamide …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Displaying drugs 9376 - 9400 of 9807 in total