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Displaying drugs 9526 - 9550 of 11731 in total
Lerociclib is under investigation in clinical trial NCT02983071 (G1T38, a CDK 4/6 Inhibitor, in Combination With Fulvestrant in Hormone Receptor-positive, Her2-negative Locally Advanced or Metastatic Breast Cancer).
Investigational
Matched Iupac: … 12'-({5-[4-(propan-2-yl)piperazin-1-yl]pyridin-2-yl}amino)-2',5',11',13'-tetraazaspiro[cyclohexane-1,3 …
Experimental
Matched Iupac: … 3-(3,6-dihydroxy-9H-xanthen-9-yl)propanoic acid …
Experimental
Matched Iupac: … (2R,3S,4S,5R,6S)-2-(hydroxymethyl)-6-{2-[(2S)-oxiran-2-yl]ethoxy}oxane-3,4,5-triol …
Investigational
Matched Synonyms: … TRANSDUCED EX VIVO WITH A SELF-INACTIVATING LENTIVIRAL VECTOR, ENCODING CODON-OPTIMIZED HUMAN INTERLEUKIN-2
CTI-01 (ethyl pyruvate) is a novel anti-inflammatory agent for the treatment of critical inflammatory conditions. CTI-01 shows a potent anti-inflammatory and tissue protection activity in multiple animal models of disease including pancreatitis, ischemia-reperfusion injury, sepsis, renal injury and endotoxemia.
Investigational
Matched Synonyms: … Ethyl 2-oxopropanoate ... Ethyl 2-oxopropionate ... 2-oxopropanoic acid ethyl ester …
Matched Iupac: … ethyl 2-oxopropanoate …
Experimental
Matched Synonyms: … 2-(Butylamino)-N-(2-chloro-6-methylphenyl)acetamide ... 2-(Butylamino)-6'-chloro-o-acetoluidide ... 2-Butylamino-6'-chloro-o-acetotoluidide …
Matched Iupac: … 2-(butylamino)-N-(2-chloro-6-methylphenyl)acetamide …
Experimental
Matched Synonyms: … phytosphingosine-2-hydroxy-18:0 ... N-2-hydroxystearoyl-phytosphingosine ... N-(2-hydroxyoctadecanoyl)phytoceramide …
Matched Iupac: … 2-hydroxy-N-[(2S,3S,4R)-1,3,4-trihydroxyoctadecan-2-yl]octadecanamide …
Experimental
Matched Synonyms: … (2S)-1-acetylpyrrolidine-2-carboxylic acid ... (S)-1-acetylpyrrolidine-2-carboxylic acid …
Matched Iupac: … (2S)-1-acetylpyrrolidine-2-carboxylic acid …
Brazikumab is under investigation in clinical trial NCT03759288 (An Active and Placebo-controlled Study of Brazikumab in Participants With Moderately to Severely Active Crohn's Disease).
Investigational
An essential amino acid. It is often added to animal feed. [PubChem]
Experimental
Dapirolizumab pegol is under investigation in clinical trial NCT02804763 (A Phase 2 Efficacy and Safety Study of Dapirolizumab Pegol (DZP) in Systemic Lupus Erythematosus).
Investigational
Matched Synonyms: … pegylated, anti-(homo sapiens cd40lg (cd40 ligand, cd40l, tumor necrosis factor ligand superfamily member 5, …
Matched Description: … Dapirolizumab pegol is under investigation in clinical trial NCT02804763 (A Phase 2 Efficacy and Safety …
Experimental
Matched Name: … 2-(acetylamino)-2-deoxy-4-O-beta-D-galactopyranosyl-alpha-D-glucopyranose …
Matched Iupac: … )oxan-2-yl]oxy}oxan-3-yl]acetamide ... N-[(2S,3R,4R,5S,6R)-2,4-dihydroxy-6-(hydroxymethyl)-5-{[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl …
Experimental
Matched Name: … O6-(R)-ROSCOVITINE, R-2-(6-BENZYLOXY-9-ISOPROPYL-9H-PURIN-2-YLAMINO)-BUTAN-1-OL …
Matched Iupac: … (2R)-2-{[6-(benzyloxy)-9-(propan-2-yl)-9H-purin-2-yl]amino}butan-1-ol …
Icotinib is a potent and specific epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) Icotinib was approved in China by the SFDA in June, 2011 and in January 2014, Beta Pharma, Inc. was given a “May Proceed” from the US FDA to conduct a Phase I study for the...
Experimental
Investigational
Matched Iupac: … N-(3-ethynylphenyl)-7H,8H,10H,11H,13H,14H-1,4,7,10-tetraoxacyclododeca[2,3-g]quinazolin-4-amine …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Liothyronine I-131 has been used in trials studying the treatment of Tricuspid Atresia and Heart Defects, Congenital.
Investigational
Matched Iupac: … (2S)-2-amino-3-{4-[4-hydroxy-3-(¹³¹I)iodophenoxy]-3,5-di(¹³¹I)iodophenyl}propanoic acid …
2'-cyano-2'-deoxy-1-(beta-D-arabinofuranosyl)cytosine has been used in trials studying the treatment of Advanced Colorectal Cancer.
Investigational
Matched Synonyms: … 2'-cyano-2'-deoxy-1-(beta-D-arabinofuranosyl)cytosine …
Matched Iupac: … (2R,3S,4S,5R)-2-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-4-hydroxy-5-(hydroxymethyl)oxolane-3-carbonitrile …
Matched Description: … 2'-cyano-2'-deoxy-1-(beta-D-arabinofuranosyl)cytosine has been used in trials studying the treatment …
A bivalent cancer vaccine comprised of a modified vaccinia virus Ankara (MVA) strain encoding human mucin 1 (MUC1) and interleukin-2 (IL-2) with potential immunostimulating and antineoplastic activities. Originally developed for the eradication of smallpox, MVA is a highly attenuated and replication-defective strain incapable of virion assembly and exerts potent immunostimulatory...
Investigational
Matched Description: … (IL-2) with potential immunostimulating and antineoplastic activities. ... Expression of IL-2 augments the specific CTL response against MUC1 expressing cells. [L5191] ... comprised of a modified vaccinia virus Ankara (MVA) strain encoding human mucin 1 (MUC1) and interleukin-2
Experimental
Matched Synonyms: … 2-Heptanamine ... 2-Aminoheptane ... 2-Heptylamine …
Matched Iupac: … heptan-2-amine …
Matched Salts cas: … 6411-75-2
Experimental
Matched Name: … 2-[({4-[2-(trifluoromethyl)phenyl]piperidin-1-yl}carbonyl)amino]benzoic acid …
Matched Iupac: … 2-({4-[2-(trifluoromethyl)phenyl]piperidine-1-carbonyl}amino)benzoic acid …
Experimental
Matched Synonyms: … 2-Aminobenzoesäure ... 2-carboxyaniline ... 2-aminobenzoic acid …
Matched Iupac: … 2-aminobenzoic acid …
Oxfenicine in an inhibitor of myocardial metabolism of nonesterified fatty acids (NEFA).
Experimental
Matched Synonyms: … L-2-(p-hydroxyphenyl)glycine …
Matched Iupac: … (2S)-2-amino-2-(4-hydroxyphenyl)acetic acid …
Investigational
Displaying drugs 9526 - 9550 of 11731 in total