Displaying drugs 1026 - 1050 of 1437 in total
Recombinant human palmitoyl protein thioesterase-1
Investigational
Matched Name: … Recombinant human palmitoyl protein thioesterase-1 …
CR002
CR002 is a novel investigational fully human monoclonal antibody that blocks the activity of excess platelet-derived growth factor-D (PDGF-D), a target shown to play a role in kidney inflammation. This is a novel therapeutic approach to treat kidney inflammation.
Investigational
Matched Synonyms: … Human monoclonal antibody against platelet-derived growth factor D …
Matched Description: … CR002 is a novel investigational fully human monoclonal antibody that blocks the activity of excess platelet-derived …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … CR002 is a novel investigational fully human monoclonal antibody that blocks the activity of excess platelet-derived …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Vestronidase alfa
Vestronidase alfa, or vestronidase alfa-vjbk, is a recombinant human lysosomal beta glucuronidase that is a purified enzyme produced by recombinant DNA technology in a Chinese hamster ovary cell line. The enzyme is a homotetramer consisted of 4 monomers with 629 amino acids, and holds the same amino acid sequence as...
Approved
Investigational
Matched Synonyms: … Recombinant human beta-glucuronidase …
Matched Description: … sequence as human beta-glucuronidase (GUS) [FDA Label]. ... spleen, heart valve abnormalities, and narrowed airways which can lead to lung infections and trouble ... The enzyme is a homotetramer consisted of 4 monomers with 629 amino acids, and holds the same amino acid …
Matched Categories: … Alimentary Tract and Metabolism ... Enzymes and Coenzymes …
Matched Description: … sequence as human beta-glucuronidase (GUS) [FDA Label]. ... spleen, heart valve abnormalities, and narrowed airways which can lead to lung infections and trouble ... The enzyme is a homotetramer consisted of 4 monomers with 629 amino acids, and holds the same amino acid …
Matched Categories: … Alimentary Tract and Metabolism ... Enzymes and Coenzymes …
Spheramine
Investigational
Matched Synonyms: … Allogeneic human retinal pigment epithelial cells on gelatin microcarriers …
Liraglutide
Victoza contains liraglutide, a synthetic analog of human glucagon-like peptide-1(GLP-1) and acts as a GLP-1 receptor agonist.[Label,A6932] Liraglutide is 97% similar to native human GLP-1, differing primarily by substituting arginine for lysine at position 34. Liraglutide is made by attaching a C-16 fatty acid (palmitic acid) with a glutamic acid...
Approved
Matched Synonyms: … N²⁶-(hexadecanoyl-gamma-glutamyle)-[34-arginine]GLP-1-(7-37)-peptide ... N²⁶-(N-Hexadecanoyl-L-gamma-glutamyl)-[34-L-arginine]glucagon-like peptide 1-(7-37)-peptide …
Matched Description: … Victoza contains liraglutide, a synthetic analog of human glucagon-like peptide-1(GLP-1) and acts as ... [Label,A6932] Liraglutide is 97% similar to native human GLP-1, differing primarily by substituting arginine …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... insulin degludec and liraglutide ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Description: … Victoza contains liraglutide, a synthetic analog of human glucagon-like peptide-1(GLP-1) and acts as ... [Label,A6932] Liraglutide is 97% similar to native human GLP-1, differing primarily by substituting arginine …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... insulin degludec and liraglutide ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Propiverine
Propiverine is a widely used antimuscarinic drug with a mixed mode of action in the treatment of symptoms associated with overactive bladder (OAB) .
Overactive bladder (OAB) is a chronic condition of the lower urinary tract characterized by urinary urgency, increased frequency of urination, and nocturia (frequent waking during the...
Approved
Investigational
Matched Description: … OAB has a negative impact on quality of life and may lead to leakage and inconvenient urinary accidents ... prevalence in men and women. ... condition of the lower urinary tract characterized by urinary urgency, increased frequency of urination, and …
Matched Categories: … Genito Urinary System and Sex Hormones ... Drugs for Urinary Frequency and Incontinence …
Matched Products: … PROPIVERIN 1A PHARMA 5MG ... PROPIVERIN 1A PHARMA 15MG …
Matched Categories: … Genito Urinary System and Sex Hormones ... Drugs for Urinary Frequency and Incontinence …
Matched Products: … PROPIVERIN 1A PHARMA 5MG ... PROPIVERIN 1A PHARMA 15MG …
Ropinirole
Ropinirole, also known as ReQuip, is a non-ergoline dopamine agonist used in Parkinson's disease and restless legs syndrome [FDA label], . It is manufactured by GlaxoSmithKline Pharmaceuticals. Ropinirole was initially approved in 1997 by the FDA [FDA label] for the management of Parkinson's disease. In 2005, it was the first...
Approved
Investigational
Matched Description: … Ropinirole, also known as _ReQuip_, is a non-ergoline dopamine agonist used in Parkinson's disease and ... offering a similar side effect profile and efficacy to previous formulations of ropinirole [A35711]. ... capsules of ropinirole were approved, allowing for less frequent dosing, therefore increased compliance, and …
Matched Products: … ROPINIROL 1A PHARMA 1MG ... ROPINIROL 1A PHARMA 2MG ... ROPINIROL 1A PHARMA 3MG …
Matched Products: … ROPINIROL 1A PHARMA 1MG ... ROPINIROL 1A PHARMA 2MG ... ROPINIROL 1A PHARMA 3MG …
Palifermin
Palifermin is a recombinant human keratinocyte growth factor (KGF). It is 140 residues long, and is produced using E. coli.
Palifermin was granted FDA approval on 15 December 2004.
Approved
Matched Synonyms: … 24-163 fibroblast growth factor 7 (human) …
Matched Description: … It is 140 residues long, and is produced using E. coli. ... Palifermin is a recombinant human keratinocyte growth factor (KGF). …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Matched Description: … It is 140 residues long, and is produced using E. coli. ... Palifermin is a recombinant human keratinocyte growth factor (KGF). …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
OptPA
Optimized tPA (OptPA; W253R/R275S-tPA) is an engineered variant of tPA designed to exhibit reduced neurotoxicity.
Investigational
Matched Synonyms: … Pptimized human tissue-type plasminogen activator …
Clozapine
Clozapine is a tricyclic dibenzodiazepine, classified as an atypical antipsychotic agent. Clozapine displays affinity to various neuroreceptors with a particularly low affinity to the dopamine receptors, thus breaking the mold of first-generation antipsychotics and deeming it "atypical". . This low affinity to dopamine receptors results in fewer extrapyramidal side effects,...
Approved
Matched Description: … side effects, notably gastrointestinal hypomotility and orthostatic hypotension. ... particularly low affinity to the dopamine receptors, thus breaking the mold of first-generation antipsychotics and ... [A185747] However, its promiscuity toward the muscarinic and adrenergic receptors can result in other …
Matched Categories: … Diazepines, Oxazepines, Thiazepines and Oxepines ... Histamine Antagonists ... Histamine H1 Antagonists ... Serotonin Agents ... Serotonin Receptor Antagonists …
Matched Products: … CLOZAPIN 25 1A PHARMA ... CLOZAPIN 50 1A PHARMA ... CLOZAPIN 100 1A PHARMA …
Matched Categories: … Diazepines, Oxazepines, Thiazepines and Oxepines ... Histamine Antagonists ... Histamine H1 Antagonists ... Serotonin Agents ... Serotonin Receptor Antagonists …
Matched Products: … CLOZAPIN 25 1A PHARMA ... CLOZAPIN 50 1A PHARMA ... CLOZAPIN 100 1A PHARMA …
Resamirigene bilparvovec
AT132 is under investigation in clinical trial NCT03199469 (Gene Transfer Clinical Study in X-linked Myotubular Myopathy).
Investigational
Matched Synonyms: … DNA (synthetic adeno-associated virus 8 vector AT132 human myotubularin cDNA-specifying) ... Non-replicating adeno-associated viral vector, serotype 8, expressing human myotubularin gene …
Exbivirumab
Exbivirumab is an investigational monoclonal antibody. It is one of the active ingredients in HepeX-B, a drug product containing two human monoclonal antibodies to the hepatitis B virus (HBV) surface antigen.
Investigational
Matched Synonyms: … with human monoclonal 19.79.5 .lambda. chain, dimer ... Immunoglobulin g, anti-(hepatitis b surface antigen) (human monoclonal 19.79.5 heavy chain), disulfide …
Matched Description: … It is one of the active ingredients in HepeX-B, a drug product containing two human monoclonal antibodies …
Matched Description: … It is one of the active ingredients in HepeX-B, a drug product containing two human monoclonal antibodies …
Libivirumab
Libivirumab is an investigational monoclonal antibody. It is one of the active ingredients in HepeX-B, a drug product containing two human monoclonal antibodies to the hepatitis B virus (HBV) surface antigen.
Investigational
Matched Synonyms: … with human monoclonal 17.1.41 .kappa. ... Immunoglobulin g, anti-(hepatitis b surface antigen) (human monoclonal 17.1.41 heavy chain), disulfide …
Matched Description: … It is one of the active ingredients in HepeX-B, a drug product containing two human monoclonal antibodies …
Matched Description: … It is one of the active ingredients in HepeX-B, a drug product containing two human monoclonal antibodies …
Fludeoxyglucose (18F)
Fludeoxyglucose F 18 Injection is a positron emitting radiopharmaceutical containing no-carrier added radioactive 2-deoxy-2-[18F]fluoro-D-g1ucose, which is used for diagnostic purposes in conjunction with Positron Emission Tomography (PET). It is administered by intravenous injection.
Approved
Investigational
Matched Categories: … Indicators and Reagents …
Matched Products: … STERIFDG 250 MBQ/ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN FLAKON, 12 DOZ …
Matched Products: … STERIFDG 250 MBQ/ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN FLAKON, 12 DOZ …
ABBV-011
ABBV-011 is an antibody-drug conjugate of humanized, cysteine-engineered IgG1 monoclonal antibody targeting seizure-related 6 homolog conjugated to N-acetyl-gamma-calicheamicin.
Investigational
Matched Synonyms: … cysteine-engineered IgG1 monoclonal antibody targeting seizure-related 6 homolog conjugated to N-acetyl-gamma-calicheamicin …
Matched Description: … cysteine-engineered IgG1 monoclonal antibody targeting seizure-related 6 homolog conjugated to N-acetyl-gamma-calicheamicin …
Matched Description: … cysteine-engineered IgG1 monoclonal antibody targeting seizure-related 6 homolog conjugated to N-acetyl-gamma-calicheamicin …
Desipramine
Desipramine hydrochloride is a dibenzazepine-derivative tricyclic antidepressant (TCA). TCAs are structurally similar to phenothiazines. They contain a tricyclic ring system with an alkyl amine substituent on the central ring. In non-depressed individuals, desipramine does not affect mood or arousal, but may cause sedation. In depressed individuals, desipramine exerts a positive...
Approved
Investigational
Matched Synonyms: … 5-(gamma-methylaminopropyl)iminodibenzyl …
Matched Description: … TCAs are potent inhibitors of serotonin and norepinephrine reuptake. ... TCAs also block histamine-H1 receptors, α1-adrenergic receptors and muscarinic ... as amitriptyline and clomipramine. …
Matched Categories: … Tricyclics and Other Norepinephrine-reuptake Inhibitors ... Histamine Antagonists ... Histamine H1 Antagonists ... Serotonin Agents ... Serotonin Modulators …
Matched Description: … TCAs are potent inhibitors of serotonin and norepinephrine reuptake. ... TCAs also block histamine-H1 receptors, α1-adrenergic receptors and muscarinic ... as amitriptyline and clomipramine. …
Matched Categories: … Tricyclics and Other Norepinephrine-reuptake Inhibitors ... Histamine Antagonists ... Histamine H1 Antagonists ... Serotonin Agents ... Serotonin Modulators …
Alunacedase alfa
Alunacedase alfa is a recombinant and soluble glycosylated form of human ACE2. This recombinant version of the enzyme has antihypertensive and potential antineoplastic activities.
Investigational
Matched Synonyms: … Recombinant Human Angiotensin-Converting Enzyme 2 …
Matched Description: … Alunacedase alfa is a recombinant and soluble glycosylated form of human ACE2. ... This recombinant version of the enzyme has antihypertensive and potential antineoplastic activities. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes …
Matched Description: … Alunacedase alfa is a recombinant and soluble glycosylated form of human ACE2. ... This recombinant version of the enzyme has antihypertensive and potential antineoplastic activities. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes …
Seviprotimut-L
Seviprotimut-L is under investigation in clinical trial NCT01546571 (Study of a Melanoma Vaccine in Stage Iib, Iic, and III Melanoma Patients).
Investigational
Matched Synonyms: … Human polyvalent shedded antigen vaccine …
Matched Description: … is under investigation in clinical trial NCT01546571 (Study of a Melanoma Vaccine in Stage Iib, Iic, and …
Matched Description: … is under investigation in clinical trial NCT01546571 (Study of a Melanoma Vaccine in Stage Iib, Iic, and …
Cardiotrophin 1
Investigational
Matched Synonyms: … Protein cardiotrophin (human isoform 1) …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
ALT-P1
ALT-P1 is a long-acting recombinant human growth hormone fused to an alpha1-antitrypsin variant. It is under investigation for the treatment of growth hormone deficiency.
Investigational
Matched Synonyms: … Recombinant human growth hormone fused to alpha1-antitrypsin variant …
Matched Description: … ALT-P1 is a long-acting recombinant human growth hormone fused to an alpha1-antitrypsin variant. …
Matched Description: … ALT-P1 is a long-acting recombinant human growth hormone fused to an alpha1-antitrypsin variant. …
Lisinopril
Lisinopril is an angiotensin converting enzyme inhibitor (ACEI) used to treat hypertension, heart failure, and myocardial infarction.[L8384,L8387,L8390] Lisinopril and captopril are the only ACEIs that are not prodrugs. It functions by inhibition of angiotensin converting enzyme as well as the renin angiotensin aldosterone system.[A184781,A184808,A184817] ACEIs are commonly used as a...
Approved
Investigational
Matched Description: … Lisinopril is an angiotensin converting enzyme inhibitor (ACEI) used to treat hypertension, heart failure, and ... [L8384,L8387,L8390] Lisinopril and [captopril] are the only ACEIs that are not prodrugs. …
Matched Mixtures name: … LISINOPRIL 1A PLUS 10/12.5 ... LISINOPRIL 1A PLUS 10/12.5 ... LISINOPRIL 1A PLUS 20/12.5 …
Matched Categories: … ACE Inhibitors and Diuretics ... ACE Inhibitors and Calcium Channel Blockers ... Amino Acids, Peptides, and Proteins ... lisinopril and diuretics ... lisinopril and amlodipine …
Matched Products: … LISINOPRIL 5 1A PHARMA ... LISINOPRIL 10 1A PHARMA ... LISINOPRIL 20 1A PHARMA …
Matched Mixtures name: … LISINOPRIL 1A PLUS 10/12.5 ... LISINOPRIL 1A PLUS 10/12.5 ... LISINOPRIL 1A PLUS 20/12.5 …
Matched Categories: … ACE Inhibitors and Diuretics ... ACE Inhibitors and Calcium Channel Blockers ... Amino Acids, Peptides, and Proteins ... lisinopril and diuretics ... lisinopril and amlodipine …
Matched Products: … LISINOPRIL 5 1A PHARMA ... LISINOPRIL 10 1A PHARMA ... LISINOPRIL 20 1A PHARMA …
Torapsel
Torapsel has been used in trials studying the prevention of Ischemia Reperfusion Injury.
Investigational
Matched Synonyms: … (HUMAN CONSTANT REGION) ... 42-89-GLYCOPROTEIN (HUMAN CLONE PMT21:PL85 P-SELECTIN GLYCOPROTEIN LIGAND-1) FUSION PROTEIN WITH IMMUNOGLOBULIN …
Ramipril
Ramipril is a prodrug belonging to the angiotensin-converting enzyme (ACE) inhibitor class of medications. It is metabolized to ramiprilat in the liver and, to a lesser extent, kidneys. Ramiprilat is a potent, competitive inhibitor of ACE, the enzyme responsible for the conversion of angiotensin I (ATI) to angiotensin II (ATII)....
Approved
Matched Description: … It is metabolized to ramiprilat in the liver and, to a lesser extent, kidneys. ... ATII regulates blood pressure and is a key component of the renin-angiotensin-aldosterone system (RAAS ... Ramipril may be used in the treatment of hypertension, congestive heart failure, nephropathy, and to …
Matched Mixtures name: … RAMIPRIL 1A PH PLU2.5/12.5 ... RAMIPRIL 1A PH PLU2.5/12.5 ... RAMIPRIL 1A PH PLU2.5/12.5 …
Matched Categories: … ACE Inhibitors and Diuretics ... ACE Inhibitors and Calcium Channel Blockers ... ramipril and felodipine ... ramipril and amlodipine ... ramipril and bisoprolol …
Matched Products: … RAMIPRIL 1A PHARMA 5 MG ... RAMIPRIL 1A PHARMA 10 MG ... RAMIPRIL 1A PHARMA 2.5 MG …
Matched Mixtures name: … RAMIPRIL 1A PH PLU2.5/12.5 ... RAMIPRIL 1A PH PLU2.5/12.5 ... RAMIPRIL 1A PH PLU2.5/12.5 …
Matched Categories: … ACE Inhibitors and Diuretics ... ACE Inhibitors and Calcium Channel Blockers ... ramipril and felodipine ... ramipril and amlodipine ... ramipril and bisoprolol …
Matched Products: … RAMIPRIL 1A PHARMA 5 MG ... RAMIPRIL 1A PHARMA 10 MG ... RAMIPRIL 1A PHARMA 2.5 MG …
Displaying drugs 1026 - 1050 of 1437 in total