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Displaying drugs 13426 - 13450 of 13784 in total

JBPOS0101

JBPOS0101 is under investigation in clinical trial NCT03976076 (A Study of Orally Administered JBPOS0101 in Refractory Infantile Spasms Patients).
Investigational
Matched Iupac: … (1S,2S)-1-(2-chlorophenyl)-1-hydroxypropan-2-yl carbamate …
Matched Description: … JBPOS0101 is under investigation in clinical trial NCT03976076 (A Study of Orally Administered JBPOS0101 …

Pecavaptan

Pecavaptan is under investigation in clinical trial NCT03901729 (A Trial to Study BAY1753011 in Patients With Congestive Heart Failure).
Investigational
Matched Iupac: … 3-(4-chlorophenyl)-1-{[1-(3-chlorophenyl)-5-[(1S)-1-hydroxyethyl]-1H-1,2,4-triazol-3-yl]methyl}-4-[(2S ... )-3,3,3-trifluoro-2-hydroxypropyl]-4,5-dihydro-1H-1,2,4-triazol-5-one …
Matched Description: … Pecavaptan is under investigation in clinical trial NCT03901729 (A Trial to Study BAY1753011 in Patients …

Uliledlimab

Uliledlimab is under investigation in clinical trial NCT04322006 (A Phase I/II Study of TJ004309 for Advanced Solid Tumor).
Investigational
Matched Description: … Uliledlimab is under investigation in clinical trial NCT04322006 (A Phase I/II Study of TJ004309 for …

Glutazumab

Glutazumab is a novel long-lasting GLP-1/anti-GLP-1R antibody fusion protein exerting anti-diabetic effects.
Investigational
Matched Description: … Glutazumab is a novel long-lasting GLP-1/anti-GLP-1R antibody fusion protein exerting anti-diabetic effects …

MRG-003

MRG-003 is a recombinant humanized anti-human epidermal growth factor receptor monoclonal antibody conjugated to monomethyl auristatin E.
Investigational
Matched Description: … MRG-003 is a recombinant humanized anti-human epidermal growth factor receptor monoclonal antibody conjugated …

CEQ508

CEQ508 is a Live Attenuated E. Coli Expressing Beta Catenin ShRNA currently being investigated to treat Familial Adenomatous Polyposis.
Investigational
Matched Description: … CEQ508 is a Live Attenuated E. …

Vamikibart

Vamikibart is under investigation in clinical trial NCT05642312 (A Study to Investigate Vamikibart in Participants With Uveitic Macular Edema).
Investigational
Matched Description: … Vamikibart is under investigation in clinical trial NCT05642312 (A Study to Investigate Vamikibart in …

Posdinemab

Posdinemab is under investigation in clinical trial NCT04619420 (A Study of JNJ-63733657 in Participants With Early Alzheimer's Disease).
Investigational
Matched Description: … Posdinemab is under investigation in clinical trial NCT04619420 (A Study of JNJ-63733657 in Participants …

Drinabant

AVE-1625 is an oral selective and potent antagonist of cannabinoid 1 (CB1) receptors having the same mechanism of action as rimonabant. It is currently developed in obesity and its associated comorbidities. AVE-1625 is also being developed for the treatment of Alzheimer disease.
Investigational
Matched Description: … AVE-1625 is an oral selective and potent antagonist of cannabinoid 1 (CB1) receptors having the same …

(2R,3R,4R,5R)-4,5-Dihydroxy-2-(hydroxymethyl)-6-oxo-3-piperidinyl beta-D-glucopyranoside

Experimental
Matched Name: … (2R,3R,4R,5R)-4,5-Dihydroxy-2-(hydroxymethyl)-6-oxo-3-piperidinyl beta-D-glucopyranoside …
Matched Iupac: … yl]oxy}piperidin-2-one ... ,5R,6R)-3,4-dihydroxy-6-(hydroxymethyl)-5-{[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2- …

Ponazuril

Ponazuril, sold by the Bayer Corporation under the trade name Marquis, is a drug currently approved for the treatment of equine protozoal myeloencephalitis in horses, caused by Sarcocystis neurona.
Vet approved
Matched Iupac: … 1-methyl-3-[3-methyl-4-(4-trifluoromethanesulfonylphenoxy)phenyl]-1,3,5-triazinane-2,4,6-trione …
Matched Description: … Ponazuril, sold by the Bayer Corporation under the trade name Marquis, is a drug currently approved for …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

(5E,7E,9)-decatrien-2-one

An compound produced by Fomitopsis betulina, an edible fungus commonly called the birch polypore. Similar to (5Z,7E,9)-decatrien-2-one, it has a strong pineapple aroma.
Experimental
Matched Name: … (5E,7E,9)-decatrien-2-one …
Matched Iupac: … (5Z,7E)-deca-5,7,9-trien-2-one …
Matched Description: … Similar to [(5Z,7E,9)-decatrien-2-one], it has a strong pineapple aroma.[A191116] …

(5Z,7E,9)-decatrien-2-one

An compound produced by Fomitopsis betulina, an edible fungus commonly called the birch polypore. Similar to (5E,7E,9)-decatrien-2-one, it has a strong pineapple aroma.
Experimental
Matched Name: … (5Z,7E,9)-decatrien-2-one …
Matched Iupac: … (5E,7E)-deca-5,7,9-trien-2-one …
Matched Description: … Similar to [(5E,7E,9)-decatrien-2-one], it has a strong pineapple aroma.[A191116] …

2'-Fucosyllactose

2'-Fucosyllactose is under investigation in clinical trial NCT03847467 (Pilot and Feasibility Study of 2'-FL as a Dietary Supplement in IBD Patients Receiving Stable Maintenance Anti-tnf Therapy).
Investigational
Matched Name: … 2'-Fucosyllactose …
Matched Iupac: … -6-methyloxan-2-yl]oxy}oxan-2-yl]oxy}-2,3,5,6-tetrahydroxyhexanal ... (2R,3R,4R,5R)-4-{[(2S,3R,4S,5R,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-{[(2S,3S,4R,5S,6S)-3,4,5-trihydroxy …
Matched Description: … 2'-FL as a Dietary Supplement in IBD Patients Receiving Stable Maintenance Anti-tnf Therapy). ... 2'-Fucosyllactose is under investigation in clinical trial NCT03847467 (Pilot and Feasibility Study of …

Survodutide

Survodutide is under investigation in clinical trial NCT06077864 (A Study to Test the Effect of Survodutide (BI 456906) on Cardiovascular Safety in People With Overweight or Obesity (SYNCHRONIZE™ - CVOT)).
Investigational
Matched Description: … Survodutide is under investigation in clinical trial NCT06077864 (A Study to Test the Effect of Survodutide …

PV903

PV903 is a self administered vaginally delivered recombinant protein for the treatment of recurrent miscarriage, resulting from an intolerant immune response to the developing foetus.
Investigational
Matched Description: … PV903 is a self administered vaginally delivered recombinant protein for the treatment of recurrent miscarriage …

Macadamia seed oil glycereth-8 esters

Macadamia seed oil glycereth-8 esters is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Description: … Macadamia seed oil glycereth-8 esters is a plant/plant extract used in some OTC (over-the-counter) products …

IONIS-FGFR4Rx

IONIS-FGFR4Rx is under investigation in clinical trial NCT02476019 (A Safety, Tolerability, PK, and PD Study of Once Weekly ISIS-FGFR4RX SC in Obese Patients).
Investigational
Matched Description: … IONIS-FGFR4Rx is under investigation in clinical trial NCT02476019 (A Safety, Tolerability, PK, and PD …

Olacaftor

Olacaftor is under investigation in clinical trial NCT02951182 (A Study Evaluating the Safety and Efficacy of VX-440 Combination Therapy in Subjects With Cystic Fibrosis).
Investigational
Matched Iupac: … N-(benzenesulfonyl)-6-[3-fluoro-5-(2-methylpropoxy)phenyl]-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine ... -3-carboxamide …
Matched Description: … Olacaftor is under investigation in clinical trial NCT02951182 (A Study Evaluating the Safety and Efficacy …

Pidacmeran

Pidacmeran is under investigation in clinical trial NCT04380701 (A Trial Investigating the Safety and Effects of Four BNT162 Vaccines Against COVID-2019 in Healthy Adults).
Investigational
Matched Description: … Pidacmeran is under investigation in clinical trial NCT04380701 (A Trial Investigating the Safety and …

Bifidobacterium Longum Infantis 35624

Bifidobacterium Longum Infantis 35624 is a probiotic being investigated for the treatment of gastrointestinal disorders, such as Crohn's disease and irritable bowel syndrome.[A259872, A259877]
Investigational
Matched Description: … Bifidobacterium Longum Infantis 35624 is a probiotic being investigated for the treatment of gastrointestinal …

CR665

CR665 is the lead clinical development candidate from a series of highly selective peripheral kappa opioid receptor agonists. In preclinical studies, CR665 was highly selective for the peripheral kappa opioid receptor. Preclinical animal studies suggest that CR665 is a potent analgesic compound. In addition, unlike currently marketed opioids, CR665 does...
Investigational
Matched Iupac: … (2R)-2-[(2R)-2-[(2R)-2-amino-3-phenylpropanamido]-3-phenylpropanamido]-N-[(1R)-4-carbamimidamido-1-{[ …
Matched Description: … Preclinical animal studies suggest that CR665 is a potent analgesic compound. ... CR665 is the lead clinical development candidate from a series of highly selective peripheral kappa opioid …

Ciluprevir

The compound, named BILN 2061, is an orally active inhibitor of the HCV NS3 protease and the first member of this new drug class to be tested in humans.
Investigational
Matched Iupac: … (1S,4R,6S,7Z,14S,18R)-14-{[(cyclopentyloxy)carbonyl]amino}-18-[(7-methoxy-2-{2-[(propan-2-yl)amino]-1,3 …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …

MIV-701

MIV-701 is a selective, potent inhibitor of the protease Cathepsin K. It is developed for the treatment of osteoporosis.
Investigational
Matched Description: … MIV-701 is a selective, potent inhibitor of the protease Cathepsin K. …

LLL-3348

The botanical drug product LLL-3348 is a once-daily oral formulation for treatment of chronic stable plaque type psoriasis.
Investigational
Matched Description: … The botanical drug product LLL-3348 is a once-daily oral formulation for treatment of chronic stable …
Displaying drugs 13426 - 13450 of 13784 in total