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Displaying drugs 15051 - 15075 of 15332 in total

A nicotinic cholinergic antagonist often referred to as the prototypical ganglionic blocker. It is poorly absorbed from the gastrointestinal tract and does not cross the blood-brain barrier. It has been used for a variety of therapeutic purposes including hypertension but, like the other ganglionic blockers, it has been replaced by...

Experimental

Matched Description: … It is poorly absorbed from the gastrointestinal tract and does not cross the blood-brain barrier. …

2-[5,6-BIS-(4-METHOXY-PHENYL)-FURO[2,3-D]PYRIMIDIN-4-YLAMINO]-ETHANOL

Experimental

5-(PARA-NITROPHENYL PHOSPHONATE)-PENTANOIC ACID

Experimental

Carmegliptin

Carmegliptin has been used in trials studying the treatment of Diabetes Mellitus Type 2.

Investigational

alpha-Fluoro-carboxymethyldethia coenzyme A complex

Experimental

Matched Iupac: … 9-yl)-4-hydroxy-3-(phosphonooxy)oxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)methyl …

Morphine glucuronide

Investigational

Matched Iupac: … (2S,3S,4S,5R,6R)-3,4,5-trihydroxy-6-{[(1S,5R,13R,14S,17R)-10-hydroxy-4-methyl-12-oxa-4-azapentacyclo[ …

XMT-1001

XMT-1001 is a polymer-based prodrug of camptothecin (CPT), a well-characterized topoisomerase I inhibitor with potent anti-tumor activity. It is a water-soluble macromolecular conjugate of camptothecin (CPT). In this novel CPT pro-drug, CPT is conjugated with a 70 kDa biodegradable hydrophilic polyacetal, poly (1-hydroxymethylene hydroxylmethylformal). XMT-1001 has demonstrated an improved therapeutic...

Investigational

Matched Description: … XMT-1001 has demonstrated an improved therapeutic window as compared with CPT and irinotecan in human …