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Displaying drugs 2026 - 2050 of 2845 in total
Ezogabine (D23129) is a close structural analog of the centrally acting analgesic flupitrine. It is a neuronal potassium channel opener being developed as a first-in-class antiepileptic drug (AED) and is currently being studied in Phase 3 trials as an adjunctive treatment for partial-onset seizures in adult patients with refractory epilepsy....
Approved
Investigational
Matched Synonyms: … N-(2-Amino-4-(4-fluorobenzylamino)-phenyl) carbamic acid ethyl ester ... N-(2-Amino-4-(4-fluorobenzylamino)phenyl)carbamic acid ethyl ester …
Matched Description: … is a neuronal potassium channel opener being developed as a first-in-class antiepileptic drug (AED) and
Matched Categories: … Acids, Acyclic ... Carboxylic Acids
Investigational
Matched Synonyms: … 3-((2,6-dichloro-7-fluoro-1-(1-propyl-1h-pyrazol-4-yl)-1h-indol-3-yl)thio)-2-fluorobenzoic acid ... Benzoic acid, 3-((2,6-dichloro-7-fluoro-1-(1-propyl-1h-pyrazol-4-yl)-1h-indol-3-yl)thio)-2-fluoro- …
Matched Iupac: … 3-{[2,6-dichloro-7-fluoro-1-(1-propyl-1H-pyrazol-4-yl)-1H-indol-3-yl]sulfanyl}-2-fluorobenzoic acid
Rosuvastatin, also known as the brand name product Crestor, is a lipid-lowering drug that belongs to the statin class of medications, which are used to lower the risk of cardiovascular disease and manage elevated lipid levels by inhibiting the endogenous production of cholesterol in the liver. More specifically, statin medications...
Approved
Matched Synonyms: … fluorophenyl)-6-(1-methylethyl)-2-(ethyl(methylsulfonyl)amino)-5-pyrimidinyl)-3,5-dihydroxy-6-heptenoic acid ... -fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl}-3,5-dihydroxyhept-6-enoic acid
Matched Iupac: … fluorophenyl)-2-(N-methylmethanesulfonamido)-6-(propan-2-yl)pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoic acid
Matched Description: … hydroxymethylglutaryl-coenzyme A (HMG-CoA) Reductase,[A181421] which catalyzes the conversion of HMG-CoA to mevalonic acid ... belongs to the statin class of medications, which are used to lower the risk of cardiovascular disease and ... referred to as "bad cholesterol"), and very low-density lipoprotein (VLDL). …
Matched Mixtures name: … Rosuvastatin and Ezetimibe ... Rosuvastatin and Ezetimibe ... Rosuvastatin and Ezetimibe …
Matched Categories: … rosuvastatin and acetylsalicylic acid ... Alimentary Tract and Metabolism ... Genito Urinary System and Sex Hormones ... rosuvastatin and valsartan ... Gynecological Antiinfectives and Antiseptics …
Experimental
Matched Name: … 2-HYDROXY-5-{[(1E)-2-PHENYLETHYLIDENE]AMINO}-L-TYROSINE
Matched Iupac: … (2S)-2-amino-3-{2,4-dihydroxy-5-[(E)-(2-phenylethylidene)amino]phenyl}propanoic acid
Investigational
Matched Synonyms: … D-norleucine, n-(((2r,6s)-2,6-dimethyl-1-piperidinyl)carbonyl)-4-methyl-l-leucyl-1-(methoxycarbonyl)-d-tryptophyl
Matched Categories: … Amino Acids, Peptides, and Proteins …
Experimental
Matched Name: … (3r)-4-(P-Toluenesulfonyl)-1,4-Thiazane-3-Carboxylicacid-L-Leucine
Matched Iupac: … (2S)-4-methyl-2-{[(3R)-4-(4-methylbenzenesulfonyl)thiomorpholin-3-yl]formamido}pentanoic acid
Omidenepag isopropyl is a topical ocular hypotensive agent used to reduce intraocular pressure (IOP) in patients with glaucoma and ocular hypertension. Omidenepag isopropyl is quickly metabolized to its active metabolite, omidenepag, a molecule with high selectivity and agonistic activity towards the prostaglandin E2 (EP2) receptor.[A253263,A253268] Prostanoid FP receptor agonists (FP...
Approved
Investigational
Matched Synonyms: … isopropyl N-(6-(((4-(1H-pyrazol-1-yl)benzyl)(3-pyridinylsulfonyl)amino)methyl)-2-pyridinyl)glycinate
Matched Iupac: … -2-yl 2-({6-[(N-{[4-(1H-pyrazol-1-yl)phenyl]methyl}pyridine-3-sulfonamido)methyl]pyridin-2-yl}amino)acetate
Matched Description: … topical ocular hypotensive agent used to reduce intraocular pressure (IOP) in patients with glaucoma and ... isopropyl is quickly metabolized to its active metabolite, omidenepag, a molecule with high selectivity and ... agonists (FP agonists), such as [latanoprost], are part of the first-line therapy for ocular hypertension and
Mimosine is an antineoplastic alanine-substituted pyridine derivative isolated from Leucena glauca.
Experimental
Matched Synonyms: … Leucenine
Matched Iupac: … (2S)-2-amino-3-(3-hydroxy-4-oxo-1,4-dihydropyridin-1-yl)propanoic acid
Matched Description: … Mimosine is an antineoplastic alanine-substituted pyridine derivative isolated from _Leucena glauca_. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Alanine ... Amino Acids
Experimental
Matched Name: … N-{[(2S,3S)-3-(ETHOXYCARBONYL)OXIRAN-2-YL]CARBONYL}-L-ISOLEUCINE
Matched Iupac: … (2S,3S)-2-{[(2S,3S)-3-(ethoxycarbonyl)oxiran-2-yl]formamido}-3-methylpentanoic acid
Ximelagatran is an anticoagulant intended to become a replacement for warfarin by overcoming the dietary restrictions, drug interaction, and monitoring issues associated with the former. In 2006, its manufacturer AstraZeneca announced that it would not attempt to market ximelagatran after reports of hepatotoxicity (liver damage) during trials, and to discontinue...
Approved
Investigational
Withdrawn
Matched Synonyms: … cyclohexyl-2- [(2S)-2-[[4-(N'-hydroxycarbamimidoyl) phenyl]methylcarbamoyl]azetidin-1-yl]- 2-oxo-ethyl]amino]acetate
Matched Iupac: … 2-[(2S)-2-[({4-[(Z)-N'-hydroxycarbamimidoyl]phenyl}methyl)carbamoyl]azetidin-1-yl]-2-oxoethyl]amino}acetate
Matched Description: … intended to become a replacement for warfarin by overcoming the dietary restrictions, drug interaction, and ... would not attempt to market ximelagatran after reports of hepatotoxicity (liver damage) during trials, and
Matched Categories: … Blood and Blood Forming Organs ... Serine Protease Inhibitors …
Experimental
Matched Name: … 2,2-Dimethylthiazolidine-4-Carboxylic Acid;(Dmt)Thiazolidine …
Matched Iupac: … (4R)-2,2-dimethyl-1,3-thiazolidine-4-carboxylic acid
Experimental
Matched Name: … 3-(Oxalyl-Amino)-Naphthalene-2-Carboxylic Acid
Matched Iupac: … 3-(carboxyformamido)naphthalene-2-carboxylic acid
Experimental
Matched Name: … 2-Amino-3-(Diethoxy-Phosphoryloxy)-Propionic Acid
Matched Iupac: … (2S)-2-amino-3-[(diethoxyphosphoryl)oxy]propanoic acid
A nucleoside monophosphate sugar which donates N-acetylneuraminic acid to the terminal sugar of a ganglioside or glycoprotein. [PubChem]
Experimental
Matched Name: … Cytidine-5'-Monophosphate-5-N-Acetylneuraminic Acid
Matched Iupac: … (hydroxy)phosphoryl)oxy]-5-acetamido-4-hydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-2-carboxylic acid
Matched Description: … A nucleoside monophosphate sugar which donates N-acetylneuraminic acid to the terminal sugar of a ganglioside …
Experimental
Matched Name: … 2-Amino-4-(Hydroxymethyl-Phosphinyl)Butanoic Acid
Matched Iupac: … (2R)-2-amino-4-[hydroxy(methyl)phosphoryl]butanoic acid
Experimental
Matched Name: … N-(M-Trifluoromethylphenyl) Phenoxazine-4,6-Dicarboxylic Acid
Matched Iupac: … 10-[3-(trifluoromethyl)phenyl]-10H-phenoxazine-4,6-dicarboxylic acid
Experimental
Matched Name: … 4-O-methyl-beta-D-glucuronic acid
Matched Iupac: … (2S,3S,4R,5R,6R)-4,5,6-trihydroxy-3-methoxyoxane-2-carboxylic acid
Experimental
Matched Name: … (2s)-4-(Beta-Alanylamino)-2-Aminobutanoic Acid
Matched Iupac: … (2S)-2-amino-4-(3-aminopropanamido)butanoic acid
Experimental
Matched Name: … P-(2'-Iodo-5'-Thenoyl)Hydrotropic Acid
Matched Iupac: … (2S)-2-[4-(5-iodothiophene-2-carbonyl)phenyl]propanoic acid
Experimental
Matched Name: … 2-[4-(2,4-Dichlorophenoxy)Phenoxy]Propanoic Acid
Matched Iupac: … (2R)-2-[4-(2,4-dichlorophenoxy)phenoxy]propanoic acid
Experimental
Matched Name: … 2-AMINO-4-CHLORO-3-HYDROXYBENZOIC ACID
Matched Iupac: … 2-amino-4-chloro-3-hydroxybenzoic acid
Experimental
Matched Name: … 5-METHYL-2-[(PHENYLSULFONYL)AMINO]BENZOIC ACID
Matched Iupac: … 2-benzenesulfonamido-5-methylbenzoic acid
Experimental
Matched Name: … 5-amino-2,4,6-tribromobenzene-1,3-dicarboxylic acid
Matched Iupac: … 5-amino-2,4,6-tribromobenzene-1,3-dicarboxylic acid
Experimental
Matched Name: … 4-[3-(dibenzylamino)phenyl]-2,4-dioxobutanoic acid
Matched Iupac: … 4-[3-(dibenzylamino)phenyl]-2,4-dioxobutanoic acid
Experimental
Matched Name: … [N-(3-dibenzylcarbamoyl-oxiranecarbonyl)-hydrazino]-acetic acid
Matched Iupac: … 2-[N-amino-3-(dibenzylcarbamoyl)-3-hydroxypropanamido]acetic acid
Displaying drugs 2026 - 2050 of 2845 in total