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Relebactam is a diazabicyclooctane beta-lactamase inhibitor, similar in structure to avibactam.[A181195,A181207] It includes a piperidine ring which reduces export from bacterial cells by producing a positive charge. It is currently available in a combination product which includes imipenem and cilastatin to treat complicated urinary tract infections (UTIs), pyelonephritis, and complicated...
Approved
Investigational
Matched Synonyms: … Relebactam anhydrous ... Relebactam
Matched Name: … Relebactam
Matched Description: … [A181207] It is currently available in a combination product which includes [imipenem] and [cilastatin ... Relebactam is a diazabicyclooctane beta-lactamase inhibitor, similar in structure to [avibactam]. ... ] to treat complicated urinary tract infections (UTIs), pyelonephritis, and complicated intra-abdominal …
Matched Salts name: … Relebactam sodium …
Imipenem is a semisynthetic thienamycin that has a wide spectrum of antibacterial activity against gram-negative and gram-positive aerobic and anaerobic bacteria, including many multiresistant strains.[label] It is stable to many beta-lactamases. Similar compounds include meropenem, known for having greater activity against Gram negative bacteria, and the newer ertapenem which exhibits...
Approved
Matched Synonyms: … Imipenem anhydrous ... Imipenem
Matched Name: … Imipenem
Matched Description: … product with cilastatin and [relebactam] which was recently approved by the FDA. ... [A15389] Imipenem is commonly used in combination with [cilastatin] and is now available in a triple-drug ... and gram-positive aerobic and anaerobic bacteria, including many multiresistant strains. …
Matched Mixtures name: … Imipenem and Cilastatin ... Imipenem and Cilastatin ... Imipenem and Cilastatin
Matched Salts name: … Imipenem monohydrate …
Matched Categories: … imipenem and cilastatin
Matched Products: … Imipenem
Displaying all 2 drugs