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Displaying all 2 drugs
Nirmatrelvir
Nirmatrelvir (PF-07321332) is an orally bioavailable 3C-like protease (3CLPRO) inhibitor that is the subject of clinical trial NCT04756531. 3CLPRO is responsible for cleaving polyproteins 1a and 1ab of SARS-CoV-2. Without the activity of the SARS-CoV-2 3CLPRO, nonstructural proteins (including proteases) cannot be released to perform their functions, inhibiting viral replication.[A234224,A234229,A234234]...
Approved
Investigational
Matched Description: … [L46921] Paxlovid was approved for use in Canada in January 2022 for the treatment of adult patients ... [L33359]
In December 2021, the FDA granted an emergency use authorization to Paxlovid, a co-packaged …
Matched Mixtures name: … Paxlovid ... Paxlovid ... Paxlovid …
Matched Mixtures name: … Paxlovid ... Paxlovid ... Paxlovid …
Ritonavir
Ritonavir is an HIV protease inhibitor that interferes with the reproductive cycle of HIV. Although it was initially developed as an independent antiviral agent, it has been shown to possess advantageous properties in combination regimens with low-dose ritonavir and other protease inhibitors. It is now more commonly used as a...
Approved
Investigational
Matched Mixtures name: … Paxlovid ... Paxlovid ... Paxlovid …
Displaying all 2 drugs