Dimethyltryptamine

DB01488IllicitInvestigationalSmall molecule

An N-methylated indoleamine derivative, a serotonergic hallucinogen found in several plants, especially Prestonia amazonica (Apocynaceae) and in mammalian brain, blood, and urine. It apparently acts as an agonist at some... It apparently acts as an agonist at some types of serotonin receptors and an antagonist at others.

Chemical structure of Dimethyltryptamine
Mechanism
Curator reviewed
Primary indication
Some people use this compound as a psychedelic inducing agent.Curator reviewed
Formula / weight
C12H16N2 · 188.2688 g/mol (avg)
Also known as
N,N-dimethyltryptamine
Code names
DEA NO. 7435 · NSC-63795

Resolves to

Compound
UNIIWUB601BHAACAS61-50-7ChEMBLCHEMBL12420ChEBI28969PubChem6089KEGGC08302
Clinical / RWD
PharmGKBPA166299581
Structure
InChIKeyDMULVCHRPCFFGV-UHFFFAOYSA-NSMILESCN(C)CCC1=CNC2=CC=CC=C12
Targets
P50406HTR6Q99720SIGMAR1P28223HTR2A

What you can answer from here — as of September 23, 2026

3Protein targetsEach mapped to UniProt, with action and pharmacological action
Listed above
707Drug interactionsStructured to mechanism, not free text
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23Clinical trialsPhase, status and sponsor resolved per trial
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18+ReferencesStructured and connected to the statements they support
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Which drugs share a target with Dimethyltryptamine, and which of those have an active Phase 3 trial?

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