Human heart cytochrome c oxidase subunit VIII. Purification and determination of the complete amino acid sequence.
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Van Kuilenburg AB, Muijsers AO, Demol H, Dekker HL, Van Beeumen JJ
Human heart cytochrome c oxidase subunit VIII. Purification and determination of the complete amino acid sequence.
FEBS Lett. 1988 Nov 21;240(1-2):127-32.
- PubMed ID
- 2847943 [ View in PubMed]
- Abstract
Subunit VIII was purified from a preparation of the human heart cytochrome c oxidase and its complete amino acid sequence was determined. The sequence proved to be much more related to that of the bovine liver oxidase subunit VIII than to that found in bovine heart. Our finding of a 'liver-type' subunit VIII in the human heart enzyme suggests that either there are no isoforms of human subunit VIII or the human oxidase does not show the type of tissue specificity that has been reported for the oxidase in other mammals.