CMY-13, a novel inducible cephalosporinase encoded by an Escherichia coli plasmid.

Article Details

Citation

Miriagou V, Tzouvelekis LS, Villa L, Lebessi E, Vatopoulos AC, Carattoli A, Tzelepi E

CMY-13, a novel inducible cephalosporinase encoded by an Escherichia coli plasmid.

Antimicrob Agents Chemother. 2004 Aug;48(8):3172-4.

PubMed ID
15273143 [ View in PubMed
]
Abstract

An IncN plasmid (p541) from Escherichia coli carried a Citrobacter freundii-derived sequence of 4,252 bp which included an ampC-ampR region and was bound by two directly repeated IS26 elements. ampC encoded a novel cephalosporinase (CMY-13) with activity similar to that of CMY-2. AmpR was likely functional as indicated in induction experiments.

DrugBank Data that Cites this Article

Polypeptides
NameUniProt ID
Dihydropteroate synthase type-1P0C002Details