N-Aminoindoline derivatives as inhibitors of 5-lipoxygenase.

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Audouin C, Mestdagh N, Lassoie MA, Houssin R, Henichart JP

N-Aminoindoline derivatives as inhibitors of 5-lipoxygenase.

Bioorg Med Chem Lett. 2001 Mar 26;11(6):845-8.

PubMed ID

11277534 [ View in PubMed

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Abstract

N-Aminoindoline derivatives were prepared and their 5-lipoxygenase inhibitory activities were evaluated in vitro and compared with those of phenidone and NDGA. Compound 4 presents the most effective 5-LO inhibition.

DrugBank Data that Cites this Article

Drug Targets

Drug	Target	Kind	Organism	Pharmacological Action	Actions
Masoprocol	Arachidonate 5-lipoxygenase	Protein	Humans	Yes	Inhibitor	Details