The effect of progesterone administration on sex hormone binding globulin binding capacity in women with severe premenstrual syndrome.

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Dalton ME

The effect of progesterone administration on sex hormone binding globulin binding capacity in women with severe premenstrual syndrome.

J Steroid Biochem. 1984 Jan;20(1):437-9.

PubMed ID

6538615 [ View in PubMed

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Abstract

Thirty-one women with severe premenstrual syndrome had low sex hormone binding globulin (SHBG) binding capacities 30.2 +/- 9.4 nmol DHT bound/l. The SHBG binding capacities rose when they were treated with three different doses of progesterone. On 400 mg (17 women) SHBG level was 45.11 +/- 11.80. On 800 mg (8 women) SHBG binding capacity rose to 64.75 +/- 14.30 and on the six women who took 1200 mg progesterone daily SHBG binding capacity was 78.5 +/- 23.10. These results are discussed.

DrugBank Data that Cites this Article

Drug Targets

Drug	Target	Kind	Organism	Pharmacological Action	Actions
Progesterone	Sex hormone-binding globulin	Protein	Humans	Unknown	Binder Potentiator	Details