Some metabolic and hormonal effects of salbutamol in man.

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Massara F, Fassio V, Camanni F, Martina V, Molinatti G

Some metabolic and hormonal effects of salbutamol in man.

Acta Diabetol Lat. 1976 May-Aug;13(3-4):146-53.

PubMed ID

1020612 [ View in PubMed

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Abstract

The effect of i.v. infusion of a beta-adrenergic stimulant, salbutamol on blood insulin, glucose, lactate, phosphates, potassium and NEFA was studied in 9 normal subjects. The effect of the drug on the blood sugar and insulin response to i.v. glucose was also examined in 4 subjects. Salbutamol was followed by increases in insulin, glucose and lactate, and a fall in blood phosphorus and potassium. NEFA values did not change significantly. These effects of salbutamol were abolished by propranolol and may thus be attributed to its beta-adrenergic stimulating action. Salbutamol also induced a reduction in glucose tolerance, in spite of the presence of enhanced blood insulin levels.

DrugBank Data that Cites this Article

Pharmaco-metabolomics

Drug	Drug Groups	Metabolite	Change	Description
Albuterol	Approved Vet Approved	Phosphorus	decreased	Albuterol decreases the level of Phosphorus in the blood
Albuterol	Approved Vet Approved	Lactate	increased	Albuterol increases the level of Lactate in the blood
Albuterol	Approved Vet Approved	Glucose	increased	Albuterol increases the level of Glucose in the blood
Albuterol	Approved Vet Approved	Potassium	decreased	Albuterol decreases the level of Potassium in the blood