Cephalexin-related nephropathy.

Article Details


Verma S, Kieff E

Cephalexin-related nephropathy.

JAMA. 1975 Nov 10;234(6):618-9.

PubMed ID
1242194 [ View in PubMed

Hematuria and eosinophilia developed in two patients being treated for bacterial endocarditis with 20 or 24 gm/day of cephalexin given orally together with probenecid (Benemid). One patient had a concurrent transient increase in serum creatinine; both patients had a history of penicillin allergy and had previously received cephalexin intravenously. All abnormalities promptly remitted following discontinuation of therapy.

DrugBank Data that Cites this Article

DrugDrug GroupsMetaboliteChangeDescription
CephalexinApproved Investigational Vet ApprovedCreatinine
Cephalexin increases the level of Creatinine in the blood