Cephalexin-related nephropathy.

Article Details

Citation

Verma S, Kieff E

Cephalexin-related nephropathy.

JAMA. 1975 Nov 10;234(6):618-9.

PubMed ID
1242194 [ View in PubMed
]
Abstract

Hematuria and eosinophilia developed in two patients being treated for bacterial endocarditis with 20 or 24 gm/day of cephalexin given orally together with probenecid (Benemid). One patient had a concurrent transient increase in serum creatinine; both patients had a history of penicillin allergy and had previously received cephalexin intravenously. All abnormalities promptly remitted following discontinuation of therapy.

DrugBank Data that Cites this Article

Pharmaco-metabolomics
DrugDrug GroupsMetaboliteChangeDescription
CephalexinApproved Investigational Vet ApprovedCreatinine
increased
Cephalexin increases the level of Creatinine in the blood