Buformin concentrations in a case of fatal lactic acidosis.

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Verdonck LF, Sangster B, van Heijst AN, de Groot G, Maes RA

Buformin concentrations in a case of fatal lactic acidosis.

Diabetologia. 1981;20(1):45-6.

PubMed ID
7202882 [ View in PubMed
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Abstract

A fatal case of lactic acidosis in a 84 year old diabetic woman taking buformin is reported. Buformin concentrations in serum, other body fluids and tissues were measured by gas chromatography. Serum buformin concentration at admission was 5.5 mg/l. Postmortem concentrations were: in serum 3.2 mg/l; in lung 2.8 mg/kg wet weight; in heart 3.0 mg/kg; in pericardial fluid 3.5 mg/l; in liver 5.2 mg/kg; in bile 6.3 mg/l; and in kidney 98 mg/kg.

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