Linezolid (ZYVOX), the first member of a completely new class of antibacterial agents for treatment of serious gram-positive infections.

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Brickner SJ, Barbachyn MR, Hutchinson DK, Manninen PR

Linezolid (ZYVOX), the first member of a completely new class of antibacterial agents for treatment of serious gram-positive infections.

J Med Chem. 2008 Apr 10;51(7):1981-90. doi: 10.1021/jm800038g. Epub 2008 Mar 14.

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18338841 [ View in PubMed

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Binding Properties

Drug	Target	Property	Measurement	pH	Temperature (°C)
Linezolid	Amine oxidase [flavin-containing] A	Ki (nM)	55000	N/A	N/A	Details