Identification of the first retinoid X, receptor homodimer antagonist.

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Canan Koch SS, Dardashti LJ, Hebert JJ, White SK, Croston GE, Flatten KS, Heyman RA, Nadzan AM

Identification of the first retinoid X, receptor homodimer antagonist.

J Med Chem. 1996 Aug 16;39(17):3229-34.

PubMed ID

8765503 [ View in PubMed

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Abstract

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DrugBank Data that Cites this Article

Binding Properties

Drug	Target	Property	Measurement	pH	Temperature (°C)
Tretinoin	Retinoic acid receptor RXR-alpha	Ki (nM)	8	N/A	N/A	Details
Tretinoin	Retinoic acid receptor RXR-beta	Ki (nM)	9	N/A	N/A	Details
Tretinoin	Retinoic acid receptor RXR-gamma	Ki (nM)	14	N/A	N/A	Details